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Traditional Chinese medicine composition, spray and preparation method for treating hand, foot and mouth disease

A technology of hand, foot and mouth disease and spray, applied in the field of traditional Chinese medicine composition for treating hand, foot and mouth disease, can solve the problems of further improvement of curative effect, high price and cost, and achieve the effect of improving diet and nutrition, convenient medication and definite curative effect

Active Publication Date: 2020-07-17
MENGCHAO HEPATOBILIARY HOSPITAL OF FUJIAN MEDICAL UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For hundreds of years in our country, clematis has been widely used as a common Chinese herbal medicine in the folk. It has been found through research that it has a certain curative effect on hand, foot and mouth disease, but the price is relatively high, and the curative effect needs to be further improved.

Method used

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  • Traditional Chinese medicine composition, spray and preparation method for treating hand, foot and mouth disease
  • Traditional Chinese medicine composition, spray and preparation method for treating hand, foot and mouth disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1: spray preparation

[0029] (1) Select fresh clematis, remove impurities, wash with clear water and dry, add an equal amount of distilled water, and send it to a grinder for crushing;

[0030] (2) put the crushed clematis juice into an ultrasonic extraction tank for extraction, the ultrasonic power is 1500w, the extraction time is controlled at 10min, and the extraction temperature is 40-50°C;

[0031] (3) the extract after the ultrasonic extraction is filtered by a centrifugal filter, the centrifugal speed is 4000r / min, and the centrifugation time is 20min, the suspended particles in the clematis juice are removed, and the clematis fresh juice without slag is obtained;

[0032] (4) Put fresh clematis juice into a vacuum degassing tank for vacuum degassing to remove dissolved oxygen. The temperature in the vacuum degassing tank is controlled at 40-50°C and the vacuum degree is 0.08-0.10MPa to obtain degassed After the clematis fresh juice;

[0033] (5) We...

Embodiment 2

[0036] Embodiment 2: clinical research

[0037] A total of 180 children with hand, foot and mouth disease who were hospitalized in our hospital from June 2011 to November 2011 were randomly divided into treatment group and control group I and control group II. There were 60 cases in the treatment group, including 31 males and 29 females. The oldest was 6 years old, the youngest was 1 year old, and the average age was 3.21±0.54 years old; the control group had 60 cases, including 33 males and 27 females, the oldest was 6 years old, the youngest was 1 year old, and the average age was 3.19±0.51 years old; The control group II included 60 cases, including 31 males and 29 females, the oldest was 7 years old, the youngest was 1 year old, and the average age was 3.21±0.56 years old. There was no significant difference in gender, age, etc. between the three groups (P>0.05), and they were comparable.

[0038] Diagnostic criteria: all conform to the diagnostic criteria of the "Guideli...

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Abstract

The invention relates to a traditional Chinese medicine composition for treatment of hand-foot-mouth disease, a spray agent and a preparation method. The traditional Chinese medicine composition for the treatment of hand-foot-mouth disease comprises the following traditional Chinese medicine raw materials by mass: 50-70 parts of fresh anoectochilus formosanus, 15-25 parts of honeysuckle, 5-20 parts of astragalus membranaceus, 5-10 parts of licorice and 1-5 parts of borneol. The beneficial effects are mainly embodied in that the anoectochilus formosanus is processed by ultrasonic extraction after crushing, a traditional high temperature decocting process is changed, the medicinal effect of the anoectochilus formosanus can be better kept, the honeysuckle, the astragalus membranaceus, and other components are added for synergistic effect, the medicinal treatment effect can be improved. The spray agent product has definite curative effect on the hand-foot-mouth disease, is convenient to use, has no adverse reaction, and has important significance for rapid healing of oral herpes / ulcers, and improvement of children's diet and nutrition.

Description

[0001] (1) Technical field [0002] The invention relates to a traditional Chinese medicine composition, a spray and a preparation method for treating hand, foot and mouth disease. [0003] (2) Background technology [0004] Hand, foot and mouth disease is a syndrome with characteristic rash and oral mucosal damage mainly caused by Coxsackie virus A16 and enterovirus EV71, which mostly occurs in infants under 5 years old. Children often suffer from pain caused by oral secretions or food stimulation, leading to crying and anorexia, which seriously affect children's diet and nutrition. Western medicine treatment of this disease currently has no specific drugs, mainly symptomatic and supportive treatment, no matter oral, intramuscular injection, or intravenous injection, all bring many difficulties and inconvenience to clinical medication, and Western medicine treatment such as antiviral drug interferon etc. Some parents have scruples about adverse drug reactions. Traditional Ch...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/898A61K9/12A61P31/14A61P1/02A61K31/045
Inventor 李芹黄德福
Owner MENGCHAO HEPATOBILIARY HOSPITAL OF FUJIAN MEDICAL UNIV
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