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New use of wild buckwheat rhizome and wild buckwheat rhizome extract in preparation of hypoglycemic medicine and healthcare food
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A health food and hypoglycemic technology, which is used in food preparation, drug combination, medical preparations containing active ingredients, etc.
Inactive Publication Date: 2012-10-17
JING BRAND
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And in the aspect of the application in the preparation hypoglycemic drug, there is no open report yet
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Embodiment 1
[0033] Preparation of Golden Buckwheat Ethanol Extract Capsules
[0034] Take 2.0 kg of dried golden buckwheat roots, grind them appropriately, and extract them 3 times with 20kg of 70% ethanol at room temperature, for the first time for 48 hours, for the second and third times for 24 hours, combine the three extractions, and extract Concentrate the extract under reduced pressure to recover ethanol, and then obtain the ethanol extract of golden buckwheat; dry the extract to obtain extract powder, add appropriate amount of starch to the extract powder, mix evenly, granulate, dry, and granulate, put into capsules, press Each capsule contains 0.20g of dried golden buckwheat and is made into 1000 capsules. Take 2 capsules each time, 3 times a day, 10 minutes before meals.
Embodiment 2
[0036] Preparation of tablets of golden buckwheat ethyl acetate extract
[0037] Prepare golden buckwheat ethanol extract by the method described in Example 1, disperse the extract in water to form a suspension 10L, add ethyl acetate by 1, 1 / 2, and 1 / 3 of the volume of the suspension, respectively Extract 3 times, combine the ethyl acetate extracts for 3 times, concentrate and recover the solvent under vacuum to obtain the ethyl acetate extract of golden buckwheat; vacuum dry below 50°C or freeze-dry at low temperature to obtain the ethyl acetate extract of golden buckwheat Material; Each tablet contains 0.1 g of ethyl acetate extract of golden buckwheat, then add appropriate amount of auxiliary materials such as starch, mix evenly, granulate, dry, and press into 1000 tablets. Take 2 tablets each time, 3 times a day, 10 minutes before meals.
Embodiment 3
[0039]The golden buckwheat ethanol extract was prepared according to the method described in Example 1, and then 0.1 g of the golden buckwheat ethanol extract was added to each tablet, and appropriate amount of auxiliary materials such as starch were added, mixed evenly, granulated, dried, and pressed into tablets. Take 2 tablets each time, 3 times a day, 10 minutes before meals.
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Abstract
The invention discloses a new use of wild buckwheat rhizome and wild buckwheat rhizome extract in preparation of hypoglycemic medicine and healthcare food, wherein a technical scheme provided by the invention is as follows: extracting the wild buckwheat rhizome to respectively obtain an ethanol extract of the wild buckwheat rhizome and an ethyl acetate extract of the wild buckwheat rhizome, then detecting the activity of the ethanol extract of the wild buckwheat rhizome and the ethyl acetate extract of the wild buckwheat rhizome by a high-throughput screening alpha-amylase inhibitor, wherein a statistical processing result displays that the wild buckwheat rhizome and the wild buckwheat rhizome extract have a strong capability of inhibiting amylase and glucosidase and can reduce the blood sugar; and activity detection model analysis in vitro and preliminary clinical curative effect observation of 140 cases of patients with diabetes display that the wild buckwheat rhizome and the wild buckwheat rhizome extract have the capability of reducing the concentration of the blood sugar in vivo; therefore, the wild buckwheat rhizome and the wild buckwheat rhizome extract provided by the invention are applicable to preparing the hypoglycemic medicine and the healthcare food.
Description
technical field [0001] The invention relates to a new application of medicinal plants, in particular to the new application of Rhizoma Fagopyri Cymosi and its extracts in the preparation of hypoglycemic drugs and health food. current technology [0002] Diabetes is one of the four deadly diseases threatening human health. A multinational joint study published online in The Lancet on June 25, 2011 showed that with population growth and aging, the global blood sugar level and the incidence of diabetes are increasing year by year, and the prevalence of diabetes worldwide is The number has grown to 347 million. On November 14, 2011, the United Nations Diabetes Day, the Diabetes Society of the Chinese Medical Association (CDS) and the International Diabetes Federation (IDF) jointly released the results of a study on the socioeconomic impact of diabetes in China, showing that the number of diabetic patients in China reached 92.4 million , China is the country with the largest nu...
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