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Application of hypericum attenuatum choisy extractive in medicine for treating bronchial asthma

A technology for bronchial asthma and hypericum, which is applied in the directions of drug combinations, medical preparations containing active ingredients, and pharmaceutical formulas, to achieve the effects of increasing stability, reducing dosage, and controlling quality.

Inactive Publication Date: 2013-01-09
TIANJIN UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there is no relevant report on the treatment of bronchial asthma with Hypericum adenatum and its extracts

Method used

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  • Application of hypericum attenuatum choisy extractive in medicine for treating bronchial asthma
  • Application of hypericum attenuatum choisy extractive in medicine for treating bronchial asthma
  • Application of hypericum attenuatum choisy extractive in medicine for treating bronchial asthma

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Embodiment Construction

[0016] Below in conjunction with the examples, the present invention is further described, the following examples are illustrative, not limiting, and the protection scope of the present invention cannot be limited by the following examples.

[0017] The present invention provides the application of the extract of Hypericum adenocarba in the medicine for treating bronchial asthma, wherein the extract of Hypericum adenocarcini is extracted from Hypericum acanthus, and the extraction is carried out according to the following steps:

[0018] ⑴ Take the shade-dried whole herb of Hypericum adenocarpus and crush it into a coarse powder, extract the active ingredients in Hypericum adenocarpus by ultrasonic extraction for 30 minutes, filter to obtain the filtrate;

[0019] (2) Concentrate the extract under reduced pressure at a temperature lower than 60°C to a clear paste with a relative density of 1.10-1.30, and put the sample on the macroporous resin column D101. The mass ratio of cle...

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Abstract

The invention relates to application of hypericum attenuatum choisy extractive in a medicine for treating bronchial asthma. According to animal experiments, the hypericum attenuatum choisy extractive has obvious relieving asthma effect on mice which are asthmatic due to histamine phosphate and acetylcholine blend liquor spray, has resisting effect on bronchus contraction caused by acetylcholine and has the effect of eliminating phlegm and relieving coughs.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and relates to the extract of Hypericum adenocarcinum, especially the application of the extract of Hypericum adenocarcinus in the medicine for treating bronchial asthma. Background technique [0002] Bronchial asthma (referred to as asthma) is a chronic airway inflammatory disease characterized by the participation of cells such as eosinophils, T lymphocytes, mast cells, and macrophages and a series of cytokines, which seriously threatens public health. Its main pathological features are acute and chronic airway inflammation, smooth muscle dysfunction and airway remodeling. According to WHO estimates, 15 million people lose their working ability due to asthma every year, accounting for 1% of the global disease burden, and the number of people who die from asthma every year worldwide It has reached 250,000 people, and patients and the society have paid a huge amount of money to contro...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P11/06A61P11/08A61P11/10A61P11/14
Inventor 张同存李秀梅罗学刚王楠李坤马宁廖兴华
Owner TIANJIN UNIV OF SCI & TECH
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