A method for dissolving L-tetrahydropalmatine, L-tetrahydropalmatine solution and application thereof

A technology of L-tetrahydropalmatine and solution, which is applied in the field of food and medicine, can solve problems such as safety hazards, unsuitability for the food industry, and non-compliance with food safety, and achieve the effects of no safety hazards, low production costs, and convenient use

Inactive Publication Date: 2016-07-06
徐志强
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, L-tetrahydropalmatine is insoluble in water, slightly soluble in ethanol, and only soluble in dilute sulfuric acid. If it is dissolved in sulfuric acid and prepared into a solution, a certain amount of sulfuric acid must be transported and stored. Contains a large safety hazard, and the use of sulfuric acid to dissolve L-tetrahydropalmatine does not meet food safety and is not suitable for the food industry

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A method for dissolving L-tetrahydropalmatine, L-tetrahydropalmatine solution and application thereof
  • A method for dissolving L-tetrahydropalmatine, L-tetrahydropalmatine solution and application thereof
  • A method for dissolving L-tetrahydropalmatine, L-tetrahydropalmatine solution and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] In an environment protected from light and at room temperature, finely weigh 25g of L-tetrahydropalmatine, accounting for 35.71‰ of the weight of shredded tobacco, slowly add 100ml of water and stir evenly, and at the same time slowly add 30ml of phosphoric acid, continue to stir evenly, and it will appear uniform, clear, light yellow liquid, the liquid is evenly sprayed onto 700g of shredded tobacco and dried for later use. In each cigarette, the dosages of shredded tobacco and L-tetrahydropalmatine are 700mg and 25mg respectively. The shredded tobacco thus obtained is rolled and packaged according to the conventional preparation method in the field of cigarettes, and a cigarette capable of suppressing addicts' craving for drugs and preventing relapse can be obtained.

Embodiment 2

[0040] In an environment protected from light and at room temperature, finely weigh 20g of L-tetrahydropalmatine, accounting for 28.57‰ of the weight of shredded tobacco, slowly add 100ml of water and stir evenly, and at the same time slowly add 8ml of phosphoric acid, continue to stir evenly, and it will appear uniform, clear, light yellow liquid, the liquid is evenly sprayed onto 700g of shredded tobacco and dried for later use. In each cigarette, the dosages of shredded tobacco and L-tetrahydropalmatine are 700mg and 20mg respectively. The shredded tobacco thus obtained is rolled and packaged according to the conventional preparation method in the field of cigarettes, and a cigarette capable of suppressing addicts' craving for drugs and preventing relapse can be obtained.

Embodiment 3

[0042] In an environment protected from light and at room temperature, finely weigh 15g of L-tetrahydropalmatine, accounting for 21.43‰ of the weight of shredded tobacco, slowly add 100ml of water and stir evenly, and at the same time slowly add 10ml of phosphoric acid, continue to stir evenly, and it will appear uniform, clear, light yellow liquid, the liquid is evenly sprayed onto 700g of shredded tobacco and dried for later use. In each cigarette, the dosages of shredded tobacco and L-tetrahydropalmatine are 700mg and 15mg respectively. The shredded tobacco thus obtained is rolled and packaged according to the conventional preparation method in the field of cigarettes, and a cigarette capable of suppressing addicts' craving for drugs and preventing relapse can be obtained.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

An L-tetrahydropalmatine dissolving method, L-tetrahydropalmatine solution and use thereof, the method comprising: adding phosphoric acid to the aqueous suspension of L-tetrahydropalmatine to dissolve the suspended L-tetrahydropalmatine; and uniformly spraying clear pale yellow L-tetrahydropalmatine solution dissolved with water and phosphoric acid onto shreded tobacco, or uniformly mixing the L-tetrahydropalmatine solution with other raw materials to prepare food or beverages.

Description

technical field [0001] The invention belongs to the field of food and medicine, and relates to a method for dissolving L-tetrahydropalmatine, a L-tetrahydropalmatine solution and applications thereof. Background technique [0002] Along with the seriousness of this social problem of drug abuse, people are developing various drug rehabilitation and drugs and preparations to prevent addicts from relapse after drug withdrawal. L-tetrahydropalmatinel (l-tetrahydropalmatinel-THP, or rotundine, also known as craniodynia), is a dopamine (DA) receptor blocker, after oral or intramuscular injection, in addition to analgesic effect, also It has a stabilizing effect, and the drug has been included in the national pharmacopoeia. Since 2005, some scholars have found that l-THP can block the discrimination effect of morphine and antagonize the behavioral sensitization effect of amphetamine. Show that it can reduce or inhibit the formation of mental dependence on morphine and amphetamine...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): B01F1/00A24B15/38A61K31/4375A61K47/04A61K9/08A61P25/36A23G4/12A23G3/36A23L2/52
CPCA24B15/302A24B15/38A61P25/36
Inventor 吴鎏桢
Owner 徐志强
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap