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Application of great burdock fruit extract in drug production or foods

A technology of burdock seed and extract is applied in the directions of application, food preparation, medical preparations containing active ingredients, etc., to achieve the effects of no adverse reactions, prevention and treatment of learning and memory decline, and significant effects

Active Publication Date: 2013-12-11
YANBIAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are no literature and patent reports on the antidepressant effect of burdock fruit extract at home and abroad.

Method used

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  • Application of great burdock fruit extract in drug production or foods
  • Application of great burdock fruit extract in drug production or foods
  • Application of great burdock fruit extract in drug production or foods

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Preparation of Burdock Fruit Extract

[0018] Take 1.0kg of burdock fruit, pulverize, add 70% ethanol to reflux and extract twice, add 10 times the amount for the first time, add 8 times the amount of solvent for the second time, reflux each time for 2.0h, combine the extracts, filter, and centrifuge ( 1000rpm, 5min.), recover ethanol under reduced pressure (50-70°C, 0.06-0.08MPa) and concentrate to an extract with a relative density of 1.10, and dry under reduced pressure to obtain 116g of dry extract powder.

Embodiment 2

[0020] The application of burdock fruit extract in medicine

[0021] Preparation of burdock fruit granule: Take 2.0kg of burdock fruit, crush it, add 70% ethanol to reflux and extract twice, add 10 times the amount for the first time, add 8 times the amount of solvent for the second time, reflux and extract for 2.0 hours each time, and combine the extracts , filter, centrifuge (1000rpm, 5min.) to separate, recover ethanol under reduced pressure (50~70℃, 0.06~0.08MPa) and concentrate to a relative density of 1.05 ～ 1.15 of the extract. Take 1 part of extract, 2 parts of sucrose, and 1 part of dextrin, mix evenly, make soft material, extrude and sieve (10-15 mesh) to make granules, dry at 60°C, granulate, pack into 200 bags, each Pack of 10g, equivalent to each bag containing 1.0g of Arctium extract.

Embodiment 3

[0023] Application of Burdock Seed Extract in Food

[0024] Burdock fruit candy: 10.0g of burdock fruit extract, 50.0g of brown granulated sugar, a little cooking oil and essence, made into 20 capsules of burdock fruit candy.

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Abstract

The invention discloses a new application of great burdock fruit extract in preparation of drugs or foods for preventing and treating depression. pharmacodynamic tests show that the great burdock fruit extract has good antidepressant effect, prevents secondary memory decline in study caused by the depression and influence of symptoms including anhedonia and the like, and can be applied to preparing the drugs or foods for preventing and treating the depression. The foods are health-caring products or food additives. The drugs can be made into medically acceptable tablets, granules, capsules, compound preparation or the like. An administration observation of 22 cases of depression suffers proves that the effective rate of the great burdock fruit extract can be 90.1%.

Description

technical field [0001] The invention belongs to the field of medicine and food, and relates to the application of burdock fruit extract in medicine or food, in particular to the new application of burdock fruit extract in medicine or food for preventing and treating depression. Background technique [0002] Depression is a mental disorder characterized by depression, slow thinking, and decreased language. Its incidence is increasing year by year, and it is the disease with the highest suicide rate in psychiatry. With the increasingly fierce social competition, people's physical and psychological pressure is increasing, and depression has become a common and frequently-occurring disease in modern society. According to the statistics of the World Health Organization, the global incidence of depression is about 11%, and it is currently the fourth largest disease in the world. Depression is projected to become the second-largest disease (after cardiovascular disease) causing a ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/28A61P25/24A23L1/30A23G3/48A61K131/00A23L33/105
Inventor 朴莲荀南极星朴虎男
Owner YANBIAN UNIV
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