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Traditional Chinese medicine composition containing pseudo-ginseng and preparation method of composition

A composition and technology of notoginseng, applied in the direction of medical preparations containing active ingredients, drug combinations, pharmaceutical formulas, etc., can solve the problems of stimulating gastric mucosa, long course of treatment, inhibition of heart function, etc., to achieve controllable quality and good curative effect Effect

Inactive Publication Date: 2014-01-15
TIANJIN TIANSHI BIOLOGICAL DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since coronary heart disease is a chronic disease, the course of drug treatment is long, and long-term use of drugs can cause serious adverse reactions such as headache, cough, stimulation of gastric mucosa, hypotension, inhibition of heart function, and damage to liver and kidney functions.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0083] Active components are extracted from the raw materials according to the following parts by weight: 3 parts of sea buckthorn, 3 parts of salvia miltiorrhiza, and 5 parts of notoginseng.

[0084] (1) Preparation of seabuckthorn extract

[0085] Take the seabuckthorn medicinal material, crush it, add ethyl acetate and 70% ethanol with a volume ratio of 1:2, heat and extract twice, the first time for 1 hour, and the second time for 1 hour, the filtrates are combined to obtain the extract I, and the dregs are added 70% ethanol, heated and refluxed for 2 times, 0.5 hours for the first time, 0.5 hours for the second time, the filtrates were combined to obtain the extract II, the combined extracts I and II were concentrated into extracts, and the extracts were dissolved with 50% ethanol. The macroporous resin AB-8 is used to separate it, first eluting with water to obtain eluent I; then eluting with 50% ethanol, and then eluting with 90% ethanol, and the elution flow rate is 1B...

Embodiment 2

[0090] Active components are extracted from the raw materials according to the following parts by weight: 30 parts of sea buckthorn, 25 parts of salvia miltiorrhiza, and 20 parts of panax notoginseng.

[0091] (1) Preparation of seabuckthorn extract

[0092] Take the seabuckthorn medicinal material, grind it, add ethyl acetate and 70% ethanol with a volume ratio of 1:2, heat and extract twice, the first time is 3 hours, the second time is 2 hours, the filtrates are combined to obtain the extract I, and the dregs are added 70% ethanol, heated and refluxed for 2 extractions, the first time was 1.5 hours, the second time was 1 hour, the filtrates were combined to obtain the extract II, the combined extracts I and II were concentrated into extracts, and the extracts were dissolved with 50% ethanol. Macroporous resin X-5 was used to separate it, firstly eluted with water to obtain eluent I; then eluted with 60% ethanol, and then eluted with 95% ethanol, and the elution flow rate wa...

Embodiment 3

[0097] Active components are extracted from the raw materials according to the following parts by weight: 5 parts of seabuckthorn, 7 parts of salvia miltiorrhiza, and 10 parts of notoginseng.

[0098] (1) Preparation of seabuckthorn extract

[0099] Take the seabuckthorn medicinal material, crush it, add ethyl acetate and 70% ethanol with a volume ratio of 1:2, heat and extract twice, the first time is 1.5 hours, the second time is 1.5 hours, the filtrates are combined to obtain the extract I, and the dregs are added 70% ethanol, heated and refluxed for 2 extractions, the first time for 1 hour, the second time for 1 hour, the filtrates were combined to obtain the extract II, the combined extracts I and II were concentrated into extracts, and the extracts were dissolved with 50% ethanol. The macroporous resin AB-8 is used to separate it, and first eluted with water to obtain eluent I; then eluted with 55% ethanol, and then eluted with 95% ethanol, and the elution flow rate is 3...

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Abstract

The invention discloses a traditional Chinese medicine composition containing pseudo-ginseng. The composition comprises the following active pharmaceutical ingredients in parts by weight: 3-30 parts of sea-buckthorn, 3-25 parts of salvia miltiorrhiza and 5-20 parts of pseudo-ginseng. The invention also discloses a preparation method of the traditional Chinese medicine composition. The preparation method comprises the steps of extracting active ingredients and preparing the finished product according to the formula. The traditional Chinese medicine composition makes the best of the treatment effects of the active pharmaceutical ingredients on cardiovascular diseases, adopts scientific matching, generates synergistic effects, has good curative effects and more controllable quality and is suitable for industrial production.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating cardiovascular diseases and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] With the continuous improvement of people's living standards, changes in diet structure, population aging is becoming more and more obvious, and the incidence of coronary heart disease is increasing day by day. Coronary heart disease is a heart disease caused by narrowing of the lumen caused by coronary atherosclerosis, which causes myocardial blood supply and oxygen supply disturbance, and is known as the "world killer". As far as the whole world is concerned, coronary heart disease has become one of the most serious diseases threatening human health in the past half century, and it is the main cause of death in the United States and some industrialized countries. According to the statistics of the World Health Organization, 24....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/537A61P9/10
Inventor 崔卜东贾林
Owner TIANJIN TIANSHI BIOLOGICAL DEV
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