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Chinese patent medicine for treating reflux esophagitis and preparation method thereof

A technology of reflux esophagitis and Chinese patent medicine, which is applied in medical formulas, medical preparations containing active ingredients, drug combinations, etc., can solve the problems of western medicines with large toxic and side effects, poor curative effect, and poor pertinence of traditional Chinese medicines. Novel dosage form, excellent effective rate and long-lasting effect

Inactive Publication Date: 2011-12-28
THE FIRST AFFILIATED HOSPITAL OF HENAN UNIV OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved in the present invention is that the existing western medicines for treating reflux esophagitis have large toxic and side effects; the technical problems of traditional Chinese medicines are poor in pertinence and curative effect, and provide a Chinese patent medicine for treating reflux esophagitis and its preparation method

Method used

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  • Chinese patent medicine for treating reflux esophagitis and preparation method thereof
  • Chinese patent medicine for treating reflux esophagitis and preparation method thereof
  • Chinese patent medicine for treating reflux esophagitis and preparation method thereof

Examples

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Effect test

Embodiment 1

[0058] 1. The Chinese patent medicine for the treatment of reflux esophagitis of the present invention, the medicament that is made of the crude drug of following weight ratio: 10~25 parts by weight of Radix Ordosae, 20~30 parts by weight of Fructus Citrifolia, 6~30 parts by weight of Radix Glycyrrhizae 15 parts by weight.

[0059] 2. the preparation method of the Chinese patent medicine for the treatment of reflux esophagitis of the present invention is carried out according to the following steps:

[0060] (1) Get 10-25 parts by weight of Rubescens first, extract 3 times with 80-90% ethanol under reflux, add 80-90% ethanol each time to be 6-8 times of the weight of Rubescens, extract 0.8-8 times each time After 1.5 hours, the reflux liquid was combined and filtered to obtain filtrate I.

[0061] (2) Combine 6 to 15 parts by weight of licorice, 20 to 30 parts by weight of fried citrus aurantium, and Dongling herb residue extracted with 80 to 90% ethanol. 10 to 14 times the ...

Embodiment 2

[0064] 1. The Chinese patent medicine for the treatment of reflux esophagitis of the present invention is a medicament made from the raw materials in the following weight ratios: 10g of Radix Ordoides, 28g of fried Citrus aurantium, and 8g of Radix Glycyrrhizae.

[0065] 2. The preparation method of the Chinese patent medicine for the treatment of reflux esophagitis is carried out according to the following steps:

[0066] (1) Get 10g of Rubescens japonicus earlier, extract 3 times with 80% ethanol reflux, add the weight of 80% ethanol each time to be 60g (6 times of the weight of Russin japonicus), extract 0.8 hour each time, merge the reflux liquid, filter, Obtain filtrate I.

[0067] (2) 8 g of licorice, 28 g of fried citrus aurantium, and Dongling herbal residue extracted by 80% ethanol were combined, decocted with water for 3 times, and the weight of adding water each time was 360 g (10 times of the total weight of the above-mentioned three medicinal materials), Decoct f...

Embodiment 3

[0070] 1. The Chinese patent medicine for the treatment of reflux esophagitis of the present invention is a medicament made from the raw materials in the following weight ratios: Radix Ordobenicum 15g, Stir-fried Citrus aurantium 23g, Radix Glycyrrhizae 10g.

[0071] 2. The preparation method of the Chinese patent medicine for the treatment of reflux esophagitis is carried out according to the following steps:

[0072] (1) Get 15g of Rubescens radix earlier, extract 3 times with 85% ethanol reflux, add the weight of 85% ethanol each time to be 105g (7 times of the weight of Rubescens radix), extract 1 hour each time, merge the reflux liquid, filter, Obtain filtrate I.

[0073] (2) 10g of licorice, 23g of stir-fried citrus aurantium and the herb residues of Dongling herb extracted by 85% ethanol were combined, decocted with water for 3 times, and the weight of adding water each time was 576g (12 times of the total weight of the above-mentioned three medicinal materials), Decoc...

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Abstract

A Chinese patent medicine for treating reflux esophagitis and a preparation method thereof belong to the field of traditional Chinese medicine preparations. The Chinese patent medicine is a medicament prepared from raw materials in the following weight proportions: 10-25 parts by weight of Radix Ordobenicum, 20-30 parts by weight of Stir-fried Fructus Citrus Aurantii, and 6-15 parts by weight of Glycyrrhizae. The medicine of the present invention is a pure traditional Chinese medicine preparation, which is a new type of gel oral preparation. After oral administration, it can adhere to the esophageal mucosa for a long time to play a local therapeutic effect. Large size, strong wall-hanging properties, continuous absorption of drugs, long-lasting drug effect, complete drug absorption, and faster curative effect. After oral administration, it can adhere to the esophageal mucosa for a long time to play a local anti-inflammatory therapeutic effect.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, and in particular relates to a Chinese patent medicine for treating reflux esophagitis and a preparation method thereof. Background technique [0002] Reflux esophagitis refers to the inflammation, erosion, ulcer and fibrosis of the esophageal mucosa caused by the reflux of stomach and (or) duodenal contents into the esophagus, which belongs to gastroesophageal reflux disease; it is a common disease , frequently-occurring disease, and smoking, drinking, diet, emotion are relevant. There are not many Chinese and Western medicines currently on the market for the treatment of reflux esophagitis. Western medicines generally take a long time, and symptoms tend to recur after drug withdrawal, and are expensive and have relatively large toxic and side effects. Ranitidine is currently the commonly used western medicine for the treatment of reflux esophagitis, but due to its stron...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/752A61P1/04
Inventor 魏明宰军华段晓颖魏群段飞杨霄张建民
Owner THE FIRST AFFILIATED HOSPITAL OF HENAN UNIV OF TCM
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