Pharmaceutical compositions and use of extract of juniperus chinensis for inhibiting angiogenesis

Abstract

The disclosure provides a pharmaceutical composition for inhibiting angiogenesis, including an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient. The pharmaceutical composition may further include a pharmaceutically acceptable carrier or salt. The disclosure also provides a method for inhibiting angiogenesis, including administering an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient for inhibiting angiogenesis to a subject in need thereof.

Description

technical field [0001] The present invention relates to a pharmaceutical composition for inhibiting angiogenesis, and in particular to a pharmaceutical composition for inhibiting angiogenesis with Juniperus chinensis extract as an active ingredient. Background technique [0002] Angiogenesis refers to the process of growing new blood vessels near the original existing blood vessels. Under the normal physiological mechanism, it can transmit the response to the stimulus by promoting angiogenesis. For example, in the process of wound healing or female menstrual cycle, there will be an angiogenesis response that is controllable and lasts for about 1-2 weeks. However, pathological angiogenesis is not controlled by normal physiological mechanisms. The regulation of angiogenesis plays a very important and balanced role in the human body. Under the action of strong angiogenesis, it may cause diabetic retinopathy, rheumatoid arthritis, or accelerate the deterioration and metastasis...

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Problems solved by technology

In addition, when the angiogenesis is excessively inhibited, it may also cause bleeding, stroke, cardiovascular disease, etc. due to the defect of coagulation function, and even affect the patient's wound healing

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