Method and system for sensitivity analysis in modeling blood flow characteristics

Abstract

Embodiments include systems and methods for determining cardiovascular information for a patient. A method includes receiving patient-specific data regarding a geometry of the patient's vasculature; creating an anatomic model representing at least a portion of the patient's vasculature based on the patient-specific data; and creating a computational model of a blood flow characteristic based on the anatomic model. The method also includes identifying one or more of an uncertain parameter, an uncertain clinical variable, and an uncertain geometry; modifying a probability model based on one or more of the identified uncertain parameter, uncertain clinical variable, or uncertain geometry; determining a blood flow characteristic within the patient's vasculature based on the anatomic model and the computational model of the blood flow characteristic of the patient's vasculature; and calculating, based on the probability model and the determined blood flow characteristic, a sensitivity of the determined fractional flow reserve to one or more of the identified uncertain parameter, uncertain clinical variable, or uncertain geometry.

Description

[0001] priority [0002] This application claims priority to U.S. Application No. 13 / 864,996, filed April 17, 2013, which claims priority to U.S. Provisional Application No. 61 / 772,401, filed March 4, 2013, which Each is incorporated herein by reference in its entirety. technical field [0003] Embodiments of the present disclosure relate to methods and systems for patient-specific modeling of blood flow and, more particularly, to methods and systems for performing sensitivity analysis in patient-specific modeling of blood flow. Background technique [0004] Coronary artery disease can cause changes in the blood vessels that supply blood to the heart, such as stenosis (abnormal narrowing of blood vessels). As a result, blood flow to the heart may be restricted. Patients with coronary artery disease may experience chest pain, which is called chronic stable angina during strenuous physical activity or unstable angina when the patient is at rest. More severe disease manifest...

AI Technical Summary

Problems solved by technology

Therefore, CCA may result in unnecessary surgery being performed on the patient, which may pose increased risk to the patient and may result in the patient paying unnecessary health care costs

Images