A compound composition for treating or protecting liver damage

A composition and liver injury technology, which is applied in drug combination, medical formula, food science, etc., can solve the problems of inaccurate effect, numerous drugs, and complicated prescriptions, and achieve the effect of exact effect, good stability, and wide range of efficacy

Active Publication Date: 2019-12-27
XIANGBEI WELMAN PHARMA CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] It can be seen that although there are many theoretical studies on liver protection of single drugs in the prior art, and there are also related compound applications, there are also defects such as a large number of drugs in the preparation, complicated prescriptions, and the specific effect is not yet accurate.

Method used

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  • A compound composition for treating or protecting liver damage
  • A compound composition for treating or protecting liver damage
  • A compound composition for treating or protecting liver damage

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Take 1.6 kg of commercially available Eclipta chinensis extract, 4.0 kg of commercially available honeysuckle extract, 0.5 kg of commercially available 10% Ganoderma lucidum polysaccharide, and 0.6 kg of commercially available tripotassium glycyrrhizinate, pass through a 60-mesh sieve, and mix well. Then add 72g of silicon dioxide as an auxiliary material, mix evenly, and fill in empty capsules at 0.22g per grain to obtain capsules.

Embodiment 2

[0057] Take 80 kg of commercially available Eclipta decoction pieces (Eclipta section), extract 4 times with 4 times (w / v) amount of water, concentrate the extract, dry, and pass through a 60-mesh sieve to obtain 7 kg of Eclipta extract; Take 40kg of commercially available Ganoderma lucidum raw medicinal material, extract 3 times with 3 times (w / v) volume of water, concentrate the extract, dry, and pass through a 60-mesh sieve to obtain 400g of Ganoderma lucidum extract;

[0058] Take 100 g of commercially available monopotassium glycyrrhizinate and 1 kg of commercially available honeysuckle extract, mix them with the extract of Eclipta chinensis and the extract of Ganoderma lucidum, and pass through a 60-mesh sieve. 0.22 g per capsule was filled into empty capsules to obtain capsules.

Embodiment 3

[0060] Take 40kg of the original medicinal material of Eclipta chinensis commercially available, extract 3 times with 5 times (w / v) amount of 70% (volume) ethanol, concentrate the extract, and dry to obtain 3.6kg of Eclipta chinensis extract; 60kg of medicinal materials were extracted 3 times with 3 times (w / v) of water, the extract was concentrated and dried to obtain 2kg of honeysuckle extract; 260g of 30% Ganoderma lucidum polysaccharide and 250g of tripotassium glycyrrhizinate were taken from the market, and mixed with Mohan The lotus extract and the honeysuckle extract are mixed uniformly, passed through a 60-mesh sieve, and filled into empty capsules at a rate of 0.22 g per capsule to obtain capsules.

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PUM

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Abstract

The invention relates to a compound composition, which comprises eclipta prostrata, honeysuckle, ganoderma Lucidum and licorice root, wherein the preferred weight ratio of each component is 16-70:10-40:1-6:1-6. According to the present invention, the composition has multiple effects of tonification, evacuation, nerve calming and the like, provides a good treatment or protection effect on liver injury, and has advantages of wide effect, exact effect, safety, stability, and the like.

Description

technical field [0001] The present invention relates to a composition, more specifically, to a compound composition with therapeutic or protective effects on liver damage. Background technique [0002] The liver is a substantial organ that undertakes important physiological functions of the human body. When pathological changes occur in the morphology and function of liver cells, liver tissue or the entire liver organ, it is called liver injury. [0003] A variety of drugs in traditional Chinese medicine can treat or maintain liver damage. Commonly used drugs include promoting blood circulation, regulating qi, clearing heat, tonifying deficiency, and calming the liver. There are many specific studies. E.g: [0004] In terms of pharmacological research: [0005] He Xuebin et al. (Experimental research on liver protection of Ganoderma lucidum polysaccharides. Chinese Journal of Integrated Traditional Chinese and Western Medicine, 2004, S1:102-104.) observed the pharmacologic...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/484A23L33/105A61P1/16
Inventor 林丽萍吕晔其他发明人请求不公开姓名
Owner XIANGBEI WELMAN PHARMA CO LTD
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