The invention relates to health care medicinal liquor. A preparation method comprises the following steps of: mixing the following components according to the weight ratio: 5g of ginseng, 8g of hairy antler, 15g of common curculigo rhizome, 20g of Chinese magnoliavine fruit, 18g of barbary wolfberry fruit, 20g of black lotus seed, 30g of Chinese yam rhizome, 20g of eucommia bark, 15g of thinleaf milkwort root-bark, 25g of epimedium herb, 25g of common cnidium fruit, 13g of radix rehmanniae preparata, 15g of membranous milkvetch root, 13g of pilose Asiabell root, 9g of Chinese thorowax root, 16g of radix angelicae sinensis, 13g of paenoiae alba, 17g of cherokee rose fruit, 15g of songaria cynomorium herb, 9g of liquorice root, 20g of desertliving cistanche, 15g of prepared common monkshood daughter root, 10g of south dodder seed, 20g of malaytea scurfpea fruit, 15g of medicinal indianmulberry root, 15g of twotooth achyranthes root, 20g of sea clam powder, 17g of himalayan teasel root and 20g of jujube honey; placing the components after mixing into a ceramic jar, and then adding 5000g of 50-degree white spirit into the ceramic jar; and covering and sealing the liquor jar, burying the lower half part of the liquor jar underground, storing for 30 days, unsealing, filtering with a filter screen, and then filling the liquor into a glass bottle for storage, thereby preparing the health care medicinal liquor disclosed by the invention.