A new method for obtaining contrast in diffusion MRI and its application

A magnetic resonance imaging and contrast technology, which is applied in the fields of application, medical science, diagnosis, etc., can solve the problems that are not applicable to the complex diffusion environment of living cells

Active Publication Date: 2018-10-26
PEKING UNIV
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Problems solved by technology

Therefore, the conventional diffusion magnetic resonance theory is not suitable for complex diffusion environments such as living cells

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  • A new method for obtaining contrast in diffusion MRI and its application
  • A new method for obtaining contrast in diffusion MRI and its application
  • A new method for obtaining contrast in diffusion MRI and its application

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Embodiment Construction

[0056] In the following description, a large number of specific details are given to facilitate a more thorough understanding of the present invention by those skilled in the art. It should be understood that what is disclosed herein is only a representative preferred embodiment. Obviously, the present invention is not limited to any specific structure, function, device, and method described herein, and may also have other embodiments or combinations of other embodiments. The number of elements described in the present invention can also be conceived as plural, unless it is clearly limited to a singular number. In addition, in order to avoid confusion between other examples and the present invention, some technical features and details that are well known in the art are not described.

[0057] The invention establishes the theory of diffuse magnetic resonance based on the fractional motion model. This theory is suitable for analyzing the magnetic resonance signals of various di...

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Abstract

The invention discloses a method for acquiring a brand new diffusion magnetic resonance imaging contrast ratio and an application of the method. Starting from the path integral formula of a fractional motion model, a signal analytical expression of diffusion magnetic resonance is obtained on the premise of making no hypothesis or approximation. The problem that a diffusion magnetic resonance signal in a living body cannot be described well based on the classical diffusion magnetic resonance theory is solved, and the theoretical blank on the aspect is filled in. The method for acquiring the brand new diffusion magnetic resonance imaging contrast ratio based on the theory is provided. Through data analysis, diffusion parameters related to water molecular movement can be obtained, and the image contrast ratio different from a traditional structure image can be provided through images of the parameters. The method and the application of the method are suitable for all fields relevant to disease diagnosis.

Description

Technical field [0001] The present invention relates to the field of magnetic resonance imaging, in particular to a method and application for obtaining a new diffusion magnetic resonance imaging contrast based on a fractional motion model. Background technique [0002] Diffusion Magnetic Resonance Imaging (diffusion Magnetic Resonance Imaging, diffusion MRI) is a special form of magnetic resonance imaging. It is currently the only method that can detect the diffusion characteristics of water molecules in vivo in vivo and non-invasively. Since its inception, it has been widely used in various research fields, such as petroleum exploration and porous media pore size measurement. In addition, clinically, diffusion magnetic resonance imaging can reveal changes in the brain or various parts of the body related to diseases such as tumors, stroke, multiple sclerosis, schizophrenia, etc. In order to describe the direction dependence of the diffusion of water molecules in biological ti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/055
Inventor 高家红范阳
Owner PEKING UNIV
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