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Integrated glioma surgical instrument

A surgical instrument and glioma technology, applied in the field of medical equipment, can solve the problems of restricting the real-time application of glioma surgery, the inability to detect deep tissue, and the inability of multi-voxel MRS to prolong the progression-free survival time and maximize the The effect of treatment, the effect of reducing the cost of treatment

Inactive Publication Date: 2018-08-17
AFFILIATED HUSN HOSPITAL OF FUDAN UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, although Raman spectroscopy has its unique advantages, because this technology is based on "light", the penetration of light is poor, and it can only detect surface substances and cannot detect deep tissues. This defect also directly restricts Real-time application of the described technique in glioma surgery
[0006] The inventor of the present application intends to provide a new type of surgical equipment carrying a Raman spectroscopy detector. At the same time, the Raman spectroscopy detection technology is used to conduct correlation research with multi-voxel MRS, and the Cho / NAA ratio and 2-HG The detection of Raman spectrum is transformed into the detection of Cho / NAA ratio and 2-HG, which effectively solves the two existing bottlenecks: 1) multi-voxel MRS cannot perform real-time detection and analysis during surgery; 2) Raman spectrum detection Unable to explore the depths of the brain

Method used

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  • Integrated glioma surgical instrument
  • Integrated glioma surgical instrument
  • Integrated glioma surgical instrument

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Embodiment 1

[0062] like Figure 1~4 As shown, the CUSA-Raman Spectra integrated brain glioma surgical instrument is composed of an ultrasonic scalpel 1, a sample box 2, a Raman spectrometer 3, a connecting device 4, and a negative pressure suction device 5; the ultrasonic scalpel 1 passes through the connecting device 4 is connected with the sample box 2, and the sample box 2 is fixed on the stage of the Raman spectrometer 3, and is connected with the negative pressure suction device 5 at the same time.

[0063] In the described device, the ultrasonic knife 1, the Raman spectrometer 3, and the negative pressure aspirator 5 are all existing equipment in production; the sample box 2 is made of silicon material to reduce the interference of the Raman peak; the connecting device 4 is usually It is made of polymer materials such as engineering plastics and PVC plastics;

[0064] The sample box 2 is a transparent cubic container made of silicon, and its external dimensions are 40 mm × 30 mm × ...

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Abstract

The invention belongs to the technical field of medical instruments and relates to an integrated glioma surgery instrument CUSA-Raman Spectra, comprising a harmonic scalpel, a sample box, a Raman spectrometer, a connector, and a vacuum extractor; the harmonic scalpel is connected with the sample box through the connector, the sample box is fixed to a stage of the Raman spectrometer and also connected with the vacuum extractor. The harmonic scalpel in the surgery instrument can break tumor tissues that are sucked into the sample box through the connector, and finally analysis is carried out through the Raman spectrometer. Results of usage show that the surgery instrument can judge the property of the tumor tissues in real time during surgery and determine tumor peripheries for the expected surgical purposes, and the surgery instrument is simple in structure, low in cost, simple to manufacture and easy to popularize.

Description

technical field [0001] The invention belongs to the field of medical instruments, and relates to a glioma surgical instrument, in particular to a CUSA-RamanSpectra integrated glioma surgical instrument; the surgical instrument has the function of real-time judging the nature of the tumor while resecting the tumor during the operation, It can be used to determine the extent of tumor resection to achieve the desired surgical effect. Background technique [0002] Glioma is the most common malignant tumor of the central nervous system and is divided into astrocytic glioma, oligodendroglioma, glioblastoma and oligoastrocytoma according to pathological type, 2007 WHO divides tumors into WHO grade I, II, III and IV tumors according to their malignancy, among which grade I and II gliomas are called low-grade gliomas, and grades III and IV gliomas are called high-grade gliomas tumor. The current treatment methods for glioma include surgical resection, radiotherapy and chemotherapy,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B17/3209A61M1/00G01N21/65
Inventor 毛颖陈亮史之峰朱侗明邹翔
Owner AFFILIATED HUSN HOSPITAL OF FUDAN UNIV
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