Simple type test device for dissolution rate of flowing pool

A test device and flow cell technology, which is applied in the direction of material inspection products, testing pharmaceutical preparations, etc., can solve the problems that hinder the application and development of the flow cell method, and the price is expensive, and achieve the effect of simple structure, convenient operation, and low price

Inactive Publication Date: 2016-07-20
YANBIAN UNIV
View PDF9 Cites 10 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the price of the flow cell method currently sold is very expensive, which hinders the application and development of the flow cell method, especially the research on the flow cell method in my country has just started, and there is no development and research on its device in China

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Simple type test device for dissolution rate of flowing pool

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0018] A simple flow cell dissolution test device includes a flow cell 6 , a filter 2 , a heating pool 19 , a solvent storage bottle 15 , a multi-channel peristaltic pump 11 and a controller 12 thereof. The middle of the flow cell 6 is a cylindrical glass with a volume of 20mL, the upper part is a ring with a frosted cross-section, the inner diameter of the ring is 22mm, and the lower part is an inverted cone, filled with glass beads 20. Bayonet and support 5 are established in the cylindrical glass, that is, a circular bayonet is provided on the inner wall of the glass, a support is placed above the bayonet, and a sample port 18 is placed on the support, such as a solid preparation. The filter 2 is a conical filter. A silica gel pad 4 is arranged between the upper port of the flow cell 6 and the upper port of the inverted filter 2 to seal and is fixedly connected with a screw 3. The lower port of the filter 2 is provided with a joint a1, and the joint a1 is connected to one e...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a simple type test device for a dissolution rate of a flowing pool. The simple type test device comprises the flowing pool, a filter, a multichannel peristaltic pump, a heating pool, a solvent storage bottle and a controller, wherein an upper opening of the flowing pool is in sealing connection with one opening of the filter; the other opening of the filter is communicated with the solvent storage bottle through a hose a; a lower opening of the flowing pool is connected with one end of a hose b; the other end of the hose b is connected with an outlet of the multichannel peristaltic pump; an inlet of the multichannel peristaltic pump is communicated with the solvent storage bottle through a hose c; the flowing pool is arranged in the heating pool. The simple type test device can work in an open or closed form; the heating temperature and the solvent flow rate are controlled; the simple type test device has the characteristics of simple structure, convenience in operation, low cost, and the like and is fit for determining the releasing rate of various drug sustained-release preparations, such as drug release brackets, implants, microspheres, microchips, lipidosome, of institutions of colleges, research institutions, pharmaceutical factory, and the like.

Description

technical field [0001] The invention belongs to the technical field of drug dissolution test, in particular to a simple flow cell dissolution test device. Background technique [0002] Dissolution test is a standard test item in the drug quality assurance system. Regardless of whether the dissolution results are related to the biological effects of the drug, the standard dissolution test is a simple and cheap method to investigate whether the physical properties of the drug are consistent. The flow cell method is a technology developed for the insurmountable difficulties in the current dissolution test methods. It is not only suitable for the dissolution test of oral solid long-release preparations such as tablets and capsules, but also suitable for drug release stents, implants, etc. Determination of the release rate of various drug sustained and controlled release preparations such as doses, microspheres, microtablets, liposomes, etc. The flow cell method has attracted th...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/15
CPCG01N33/15
Inventor 朴相范李东浩方亮
Owner YANBIAN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap