Simple type test device for dissolution rate of flowing pool

Abstract

The invention discloses a simple type test device for a dissolution rate of a flowing pool. The simple type test device comprises the flowing pool, a filter, a multichannel peristaltic pump, a heating pool, a solvent storage bottle and a controller, wherein an upper opening of the flowing pool is in sealing connection with one opening of the filter; the other opening of the filter is communicated with the solvent storage bottle through a hose a; a lower opening of the flowing pool is connected with one end of a hose b; the other end of the hose b is connected with an outlet of the multichannel peristaltic pump; an inlet of the multichannel peristaltic pump is communicated with the solvent storage bottle through a hose c; the flowing pool is arranged in the heating pool. The simple type test device can work in an open or closed form; the heating temperature and the solvent flow rate are controlled; the simple type test device has the characteristics of simple structure, convenience in operation, low cost, and the like and is fit for determining the releasing rate of various drug sustained-release preparations, such as drug release brackets, implants, microspheres, microchips, lipidosome, of institutions of colleges, research institutions, pharmaceutical factory, and the like.

Description

technical field [0001] The invention belongs to the technical field of drug dissolution test, in particular to a simple flow cell dissolution test device. Background technique [0002] Dissolution test is a standard test item in the drug quality assurance system. Regardless of whether the dissolution results are related to the biological effects of the drug, the standard dissolution test is a simple and cheap method to investigate whether the physical properties of the drug are consistent. The flow cell method is a technology developed for the insurmountable difficulties in the current dissolution test methods. It is not only suitable for the dissolution test of oral solid long-release preparations such as tablets and capsules, but also suitable for drug release stents, implants, etc. Determination of the release rate of various drug sustained and controlled release preparations such as doses, microspheres, microtablets, liposomes, etc. The flow cell method has attracted th...

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Problems solved by technology

However, the price of the flow cell method currently sold is very expensive, which hinders the application and development of the flow cell method, especially the research on the flow cell method in my country has just started, and there is no development and research on its device in China

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