13 results about "Dissolution testing" patented technology

The invention relates to a dissolution testing method for soluble metal, and in the whole period of sample dissolution testing, dissolution products are separated and quantitatively recorded, and then dissolution rate is obtained, fed back in time and completely recorded. According to the invention, the dissolution condition and rate of the material can be recorded in real time, and the obtained dissolution rate data is real and accurate; in the dissolution testing process, the device is completely automatic, simple to operate, timely and accurate.

This invention provides a CO2 dynamic dissolution testing device. The device includes: a core holder, a vacuum system, a confining pressure system, a back pressure system, a fluid supply system, a nuclear magnetic resonance (NMR) testing system, a sensor system, and a temperature control system. The fluid supply system includes a CO2 gas supply component, a formation water supply component, a saturated carbon dioxide formation water supply component, and a helium supply component. The helium supply component includes a helium cylinder and a standard gas chamber, with the gas outlet of the helium cylinder connected to the inlet of the standard gas chamber. The CO2 gas supply component, formation water supply component, saturated carbon dioxide formation water supply component, and standard gas chamber are each connected to the fluid inlet of the core holder. The sensor system includes a pressure sensor group, comprising a pressure sensor for acquiring the pressure at the fluid inlet of the core holder, a pressure sensor for acquiring the pressure at the fluid outlet of the core holder, and a pressure sensor for acquiring the pressure of the standard gas chamber.

A fiber-optic transmission probe system for, for example, dissolution testing, includes a single probe, a single probe tip, and a number of pathlength adjusters of different lengths. The transmission probe system is usable to assemble different probe assemblies having different, desired optical pathlengths, where each probe assembly has either no pathlength adjuster or a different one of the pathlength adjusters. The probe system avoids the prior-art requirements of having either (i) multiple probes of different, fixed optical pathlengths or (ii) a probe with multiple probe tips of different, fixed lengths to achieve the different, desired optical pathlengths.

The utility model relates to the technical field of western medicine dissolution testing, and discloses a western medicine dissolution testing and analyzing device which comprises a bottom plate, a base and a machine head box, three groups of placing grooves are evenly distributed in the top of the base, grooves are formed in the positions, located on the two sides of the placing grooves, in the top of the base, and magnetic attraction blocks are fixed in the grooves. And the iron sheets are in one-to-one correspondence with the grooves in position. The placement groove is formed in the top of the base and used for containing the dissolution cup, the base is transparent and used for observation and analysis of the dissolution rate by workers, the grooves are formed in the positions, located on the two sides of the placement groove, in the top of the base, and the magnetic attraction blocks are fixed in the grooves. When the dissolving cup is used, the iron sheet is bonded and fixed at the bottom of the cup edge plate by using the glue layer, so that when the dissolving cup is placed, the cup edge plate is positioned above the base, and the iron sheet is positioned at the position of the groove and is matched with the magnetic suction block to form adsorption positioning, so that the stability is improved.

The invention relates to the technical field of oral non-biological medicine preparations, in particular to a method for detecting a dissolution curve of an upatinib sustained release tablet. The invention discloses a method for detecting a dissolution curve of an upatinib sustained-release tablet, and aims to provide a method suitable for detecting the dissolution curve of the upatinib sustained-release tablet, and the method for detecting the dissolution curve of the upatinib sustained-release tablet comprises the following steps: respectively dissolving an organic matter solution to be detected and an upatinib sustained-release tablet solution of a control preparation in a plurality of dissolution solutions. Carrying out a dissolution rate test by utilizing a basket method, and detecting a dissolution solution for multiple times by adopting a high performance liquid chromatograph to obtain a detection result of the organic matter solution to be detected and a detection result of an upatinib sustained release tablet solution of a control preparation; comparing the two detection results, and if the similarity factor of the detection result of the to-be-detected organic matter solution and the detection result of the upatinib sustained-release tablet solution of the control preparation is greater than 50, determining that the dissolution behavior of the to-be-detected organic matter is similar to that of the control upatinib sustained-release tablet, and determining that the to-be-detected organic matter is the upatinib sustained-release tablet.

A (e.g., dissolution) testing system has one or more stationary reader units and one or more corresponding rotatable shaft assemblies. Each reader unit has reader circuitry electrically connected to a reader antenna. Each shaft assembly has shaft circuitry electrically connected to a temperature sensor and a shaft antenna. The reader circuitry controls the reader antenna to wirelessly convey electrical energy to the shaft circuitry via the shaft antenna. The shaft circuitry controls the shaft antenna based on temperature measurements from the temperature sensor to wirelessly convey corresponding temperature information to the reader circuitry via the reader antenna. The testing system may employ a Near-Field Communication protocol to convey both the electrical energy and the temperature information.

This invention provides a capsule shell solubility testing device, belonging to the field of pharmaceutical production and processing testing technology. The device features a simple, flexible, and adjustable structure, easy operation, and good testing results. The testing tank is shaped like an inverted frustum, with an open, large-diameter end facing upwards. Multiple lifting baskets are suspended within the tank's interior. Each basket is secured with a lifting cable via fixed lugs. Multiple winding machines are located outside the tank, with the lifting cables wound around them. The winding machines control the raising and lowering of the baskets. A central column stands vertically along its axis within the tank's interior, with a rotating arm mounted on top. A camera is fixedly suspended on the lower surface of the rotating arm's cantilevered end. This device offers flexible structure, independent testing tanks, smooth basket lifting, reduced interference, and high physiological environment fidelity, resulting in high testing accuracy.

The invention relates to a dissolution testing device and method for a soluble metal material, the dissolution testing device comprises a corrosion reaction unit, the corrosion reaction unit is connected with a corrosion solution storage unit and a gas detection unit, the corrosion solution storage unit is connected with the corrosion reaction unit through a circulation unit, and the gas detection unit is provided with a flow metering device. And the gas detection unit is used for detecting the amount of gas generated in the corrosion reaction unit, the pressure in the corrosion reaction unit is controlled to be 1-3.5 standard atmospheric pressures, and the boiling point of the corrosion solution is maintained at a certain constant temperature between 100 DEG C and 250 DEG C. According to the invention, the dissolution condition and rate of the material can be recorded in real time, and the obtained dissolution rate data is real and accurate; in the dissolution test process, only the amount of generated hydrogen needs to be measured, and the operation is simple and accurate; the dissolution rate of the sample at the temperature of 100 DEG C or above can be tested.

This utility model discloses a fully automatic quantitative fiber dissolution testing device, including a frame, a reagent tank, a water tank, a waste liquid tank, and a dissolution container. The reagent tank and water tank are installed on the top of the frame, the dissolution container is installed in the middle of the frame, and the waste liquid tank is installed at the bottom of the frame. The reagent tank and water tank are connected to the dissolution container through pipes, and the dissolution container is connected to the waste liquid tank through pipes. An aeration and stirring device is installed on the frame above the dissolution container. When stirring is required, the aeration and stirring device aerates the dissolution container. This utility model, through the reasonable layout of the components, utilizes the aeration and stirring device to effectively stir the substances in the dissolution container. Furthermore, the reagent tank and water tank adopt a specific structure and are equipped with level gauges for liquid level monitoring.

The invention relates to a dissolution test device for dissolving a soluble substance in a dissolution medium, comprising at least one reservoir (15) for the dissolution medium, a plurality of dissolution units (4) each designed to receive the soluble substance to be tested, and a pump device for adding the dissolution medium to the units (4). A plurality of units (4) are arranged in a common heating channel (100), with a heater (101) connected to the heating channel (100) for heating a gaseous heating medium, such as hot air, in the heating channel (100).

A (e.g., dissolution) testing system has one or more stationary reader units and one or more corresponding rotatable shaft assemblies. Each reader unit has reader circuitry electrically connected to a reader antenna. Each shaft assembly has shaft circuitry electrically connected to a temperature sensor and a shaft antenna. The reader circuitry controls the reader antenna to wirelessly convey electrical energy to the shaft circuitry via the shaft antenna. The shaft circuitry controls the shaft antenna based on temperature measurements from the temperature sensor to wirelessly convey corresponding temperature information to the reader circuitry via the reader antenna. The testing system may employ a Near-Field Communication protocol to convey both the electrical energy and the temperature information.

The invention relates to a dissolution testing device for testing a soluble substance dissolved in a dissolution medium, comprising at least one dissolution medium reservoir (15), at least one flow cell (4) for receiving the soluble substance to be tested, and at least one pump device (60) for pumping the dissolution medium through the at least one flow cell (4). Furthermore, the dissolution test device comprises at least two sampling containers (8.1, 8.2) connectable to a flow cell (4) for sampling a substance solution, an inlet fluid manifold (100) for selectively connecting the flow cell (4) to one of the at least two sampling containers (8.1, 8.2), an outlet fluid manifold (200) for selectively connecting the at least two sampling containers (8.1, 8.2) to the other of the at least two sampling containers (8.1, 8.2), and a flow cell (3) for selectively connecting the flow cell (4) to the other of the at least two sampling containers (8.1, 8.2). 8.1; 8.2) to an outlet fluid manifold (110) of the discharge line (140) for connecting one of the selected sampling containers (8.1; 8.2), and a switching valve system (150) for selectively connecting the discharge line (140) to the cell inlet line (27) or the extraction line (160) of the flow cell (4).

The invention relates to the technical field of medicine feeding and sampling integrated devices, in particular to an automatic medicine feeding and continuous sampling integrated device of a medicine dissolution tester, which comprises a supporting part, a box body and a plurality of sample storage tubes, and further comprises a plurality of medicine dissolving parts, a stirring part, a sampling part, a cleaning part and an external hanging part, the medicine dissolving cylinder is placed in the box body, and the top of the medicine dissolving cylinder is higher than the box body; the number of the stirring parts is the same as that of the medicine dissolving parts, and the stirring parts are arranged on the supporting part, can extend into the medicine dissolving parts, are used for containing medicines needing to be dissolved and can stir solvents in the medicine dissolving parts. According to the invention, the medicine storage component is detachably integrated on the stirring part and is driven by the stirring part to rotate in the dissolution medium, so that automatic release and mixing of medicines are realized. The medicine is placed in the medicine storage cylinder and exchanges with the solvent through the through holes, so that the problem of over-high local concentration caused by traditional direct dosing is avoided, and the accuracy of data at the initial stage of dissolution is improved.