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Method for analyzing biological evolution law through entropy change

A technology of biological evolution and entropy change, applied in the field of analysis of biological evolution laws, can solve the problems of the correctness of the neutral theory and the inconclusive scope of application

Pending Publication Date: 2017-05-17
XINJIANG UNIVERSITY
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Problems solved by technology

In 1968, Japanese geneticist Shio Kimura put forward the neutral theory based on the protein sequence, arguing that biological evolution is not affected by natural selection at the molecular level, but random mutations that are neither beneficial nor harmful to biological survival at a certain rate , some experiments have shown that the change of DNA sequence is more in line with the neutral theory, and the correctness and scope of application of the neutral theory are still inconclusive

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  • Method for analyzing biological evolution law through entropy change
  • Method for analyzing biological evolution law through entropy change
  • Method for analyzing biological evolution law through entropy change

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Embodiment Construction

[0021] Embodiment The method for analyzing the law of biological evolution by entropy change

[0022] The method of analyzing the law of biological evolution through entropy change includes the introduction of the concept of effective volume and free volume of biomolecules, the definition of entropy change function, the calculation of effective entropy change and free entropy change of biological materials, and the analysis of biological evolution law. The definition of entropy change function, the law of biological evolution can be obtained through the calculation and analysis of effective entropy change and free entropy change of biological materials.

[0023] (1) The introduction of the concepts of effective volume and free volume of biomolecules

[0024] The effective volume of biomolecules refers to the volume of space that contains the interaction between biomolecules and the internal and external fields on molecules. Represents; the free volume of biomolecules refers ...

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Abstract

The invention provides a method for analyzing a biological evolution law through entropy change. The method includes introduction of biomolecule effective volume and free volume concept, definition of an entropy change function, calculation of effective entropy change and free entropy change, analysis of the biological evolution law. Preferably, the method for analyzing the biological evolution law through entropy change also includes introduction of biomolecule effective volume and free volume concept, definition of the entropy change function, calculation of effective entropy change and free entropy change; the biological evolution law can be acquired through calculation of effective entropy change and free entropy change of biological materials, and a new analysis method and theoretical direction are provided for research and development of structural biology, molecular biology, cell biology, developmental biology, genetics and evolutionary biology.

Description

technical field [0001] The invention relates to a method for analyzing the law of biological evolution through entropy change, in particular to a method for calculating the effective entropy change and free entropy change of biological materials by introducing the concept of effective volume and free volume of biomolecules, based on the definition of entropy change function , The method of analyzing the law of biological evolution. Background technique [0002] In 1850, German physicist Rudolf Clausius first proposed the concept of entropy, which is used to indicate the uniformity of any kind of energy distribution in space. The more uniform the energy distribution, the greater the entropy. When the energy of a system is completely evenly distributed, the entropy of the system reaches its maximum value. According to Clausius, in a system, if it is allowed to develop naturally, then the energy difference always tends to eliminate. Put a hot object in contact with a cold obj...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F19/12G06F19/14G16B10/00
CPCG16B5/00G16B10/00
Inventor 陈恒雷崔秀花吕长武
Owner XINJIANG UNIVERSITY
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