Traditional Chinese medicine composition for preventing and treating rheumatoid arthritis

A rheumatoid and composition technology, applied in the field of medical inventions, can solve the problems of high price, patients cannot achieve curative effect, limited wide application, etc., and achieve the effect of exact curative effect

Inactive Publication Date: 2017-06-16
宋淑芹
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the clinical application of existing drugs, many patients cannot achieve good curative effect, or cannot adhere to long-term medication due to side effects
In addition, in developing countries, the use of some effective biological products is limited, and some factors such as high prices limit their wide application

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Embodiment 1: the granule of preventing and treating rheumatoid arthritis

[0038] 1. Raw materials of traditional Chinese medicine: Paofuzi 10kg, Guizhi 12kg, Atractylodes macrocephala 15kg, Selaginella 9kg.

[0039] 2. Preparation method:

[0040] 1) Soak Guizhi, Atractylodes macrocephala, and Selaginella selaginella with water 8 times its weight for 30 minutes, and set aside;

[0041] 2) Put Fuzi Paofuzi in a stainless steel decocting pot, add water 8 times its weight, first soak for 30 minutes, then decoct with a slow fire for 30 minutes, add the medicine and soaking liquid prepared in step 1), decoct for 1.5 hours, and use Four layers of gauze filter to collect the filtrate;

[0042] Add 6 times of dregs for the second time and decoct for 1h, filter with four layers of gauze, combine the decoctions decocted twice, and the filtrate is concentrated to a relative density of 1.10 (30°C), then dried and pulverized, namely Get Chinese medicine extract.

[0043] Accor...

Embodiment 2

[0044] Embodiment 2: Capsules for preventing and treating rheumatoid arthritis

[0045] 1. Raw materials of traditional Chinese medicine: Paofuzi 15kg, Guizhi 20kg, Atractylodes macrocephala 10kg, Selaginella 6kg.

[0046] 2, preparation method: with embodiment 1.

Embodiment 3

[0047] Embodiment 3: the injection of preventing and treating rheumatoid arthritis

[0048] 1. Raw materials of traditional Chinese medicine: Paofuzi 10kg, Guizhi 12kg, Atractylodes macrocephala 15kg, Selaginella 9kg.

[0049] 2. Preparation method: 1) Take the medicinal materials according to the proportioning ratio, then add 8 times the amount of 30% ethanol, reflux extraction for 2 hours, filter, and collect the filtrate;

[0050] 2) Step 1) The remaining medicinal residues were extracted with 5 times the amount of 30% ethanol under reflux for 1.5 hours, filtered, and the filtrate was collected;

[0051] 3) Combine the filtrates of steps 1) and ), recover ethanol under reduced pressure, concentrate in a water bath (60C) until the concentrated solution with a relative density of 1.03 is dried, and pulverized into fine powder to obtain the Chinese medicine extract.

[0052] 4) Dilute the Chinese medicine extract to 320mg / ml with water for injection, filter at 0.22um, and ste...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for preventing and treating rheumatoid arthritis. The traditional Chinese medicine composition is made of the following traditional Chinese medicines in parts by weight : 5-20 parts of Paofuzi, 5-30 parts of Guizhi, 5-30 parts of Atractylodes macrocephala, and 5-20 parts of Selaginella. The invention also provides a preparation containing the traditional Chinese medicine composition and a preparation method thereof. Experiments have proved that the traditional Chinese medicine composition provided by the invention has definite curative effect on treating rheumatoid arthritis.

Description

technical field [0001] The invention relates to the field of medical inventions, in particular to a traditional Chinese medicine composition for preventing and treating rheumatoid arthritis and a preparation method thereof. Background technique [0002] Rheumatoid arthritis (rheumatoid arthritis, RA) is a chronic, systemic autoimmune system disease with unknown etiology, mainly involving joint destruction. The rate is higher than that of men, and the ratio of men to women is about 1: 3. The main pathological links include synovial inflammation and hyperplasia, pannus formation, and destruction of cartilage and bone tissue. Clinical studies have found that the degree of neovascularization in RA joints is positively correlated with the patient's condition, the degree of synovial hyperplasia and inflammatory cell infiltration, and drugs that inhibit angiogenesis can alleviate the condition of RA. [0003] [3] Currently, the commonly used clinical drugs for the treatment of rh...

Claims

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Application Information

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Patent Type & AuthorityApplications(China)
IPC IPC(8): A61K36/714A61P19/02A61P29/00
CPCA61K36/714A61K9/0019A61K9/08A61K9/1623A61K9/4866A61K36/11A61K36/284A61K36/54A61K2236/331A61K2236/39
Inventor宋淑芹
Owner宋淑芹