Adaptive replanning based on multimodality imaging

A technique of planning and treatment planning, applied in law. , the point will be obvious from the following description, it can solve the time-consuming and difficult problems of complete automation

Active Publication Date: 2017-08-18
THE MEDICAL COLLEGE OF WISCONSIN INC
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, challenges remain with such online replanning schemes as they require delineation of the target and OAR, which is a time-consuming and difficult process to fully automate

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  • Adaptive replanning based on multimodality imaging
  • Adaptive replanning based on multimodality imaging
  • Adaptive replanning based on multimodality imaging

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Embodiment Construction

[0041] Current clinical practice associated with the delivery of any one or more radiation therapy treatments includes complex, carefully coordinated workflows, employing a multitude of tools and systems designed to achieve maximum patient benefit. figure 1 An example flowchart showing the general steps associated with such a radiation therapy treatment procedure is shown. Process 100 typically begins at process block 10, where medical image information is typically generated from a patient using various imaging methods for diagnostic or therapeutic purposes. For example, as in figure 1 As shown in , this can include the use of computed tomography (CT) devices, magnetic resonance imaging (MRI) devices, positron emission tomography (PET) imaging devices, ultrasound (US) imaging devices, and the like. Information obtained from imaging is used for two main purposes in radiation therapy (RT). First, it is used to determine the true three-dimensional location and extent of target...

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Abstract

Systems and methods directed to adaptive radiotherapy planning are provided. In some aspects, provided system and method include producing synthetic images from magnetic resonance data using relaxometry maps. The method includes applying corrections to the data and generating relaxometry maps therefrom. In other aspects, a method for adapting a radiotherapy plan is provided. The method includes determining an objective function based on dose gradients from an initial dose distribution, and generating an optimized plan based on updated images, using aperture morphing and gradient maintenance algorithms without need for organ-at-risk contouring. In yet other aspects, a method for obtaining 4D MR imaging using a temporal reshuffling of data acquired during normal breathing, a method for deformable image registration using a sequentially applied semi-physical model regularization method for multimodality images, and a method to generate 4D plans using an aperture morphing algorithm based on 4D CT or 4D MR imaging are provided.

Description

[0001] Cross References to Related Applications [0002] This application claims the serial number of U.S. Provisional Patent Application entitled "SYSTEMS AND METHODS FOR ADAPTIVEREPLANNING BASED ON MULTI-MODALITY IMAGING," filed December 31, 2013 Priority of No. 61 / 922,343. Background technique [0003] The present disclosure relates generally to tools, systems, and methods for use in radiation therapy treatment delivery and, more particularly, to systems and methods for multimodal imaging-based adaptive planning. [0004] Radiation therapy (RT) has undergone a series of technological revolutions over the past few decades. With intensity modulated RT (IMRT), it becomes possible to generate a highly conformal dose distribution whereby most of the radiation dose is delivered within the confines of the tumor. These techniques utilize 3D anatomical and biological information extracted from images of various types (eg, CT, MRI, PET) acquired days before the first treatment. Ho...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/103A61N5/10G06F17/00
CPCA61N5/1038A61N5/1037A61B5/055A61B5/7289A61B6/032A61B6/037A61B6/4417A61B6/5247A61B8/4416A61B8/483A61B8/5261G06T7/11A61N5/1039A61B5/0036G06F18/24G06T11/003G06T2207/10012G06T2207/10076G06T2207/10081G06T2207/10088
Inventor X·A·李E·S·保尔森E·阿汉贝C-g·杨V·哈特
Owner THE MEDICAL COLLEGE OF WISCONSIN INC
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