Fever cooling patch prepared by combining acetaminophen and radix bupleuri volatile oil and preparation method

Abstract

The invention discloses a fever cooling patch prepared by combining acetaminophen and radix bupleuri volatile oil and a preparation method. The fever cooling patch comprises 50 to 400 mg of the acetaminophen, 0.5 to 1.0 micro-litre of the radix bupleuri volatile oil, and a fever cooling patch substrate; the preparation method comprises the following steps: mixing the acetaminophen, the radix bupleuri volatile oil and the fever cooling patch substrate; coating a position between a back lining material and a cover lining material with the mixed fever cooling patch substrate, wherein the radix bupleuri volatile oil is the volatile oil which is extracted from radix bupleuri which is subjected to biological enzymolysis by utilizing distilling. Through the technical scheme disclosed by the invention, an adverse reaction of an orally taken medicament to a gastrointestinal tract is reduced, the possibility of damage to the liver and the kidney is reduced, the fever cooling duration is prolonged, and a fever cooling effect is enhanced.

Description

technical field [0001] The invention relates to the technical field of application of Chinese and Western medicines, in particular to an antipyretic patch prepared by combining acetaminophen and bupleurum volatile oil and a preparation method of the antipyretic patch. Background technique [0002] Fever is one of the most common clinical symptoms in pediatrics, usually caused by virus, bacterial infection or other diseases. Fever is a protective response of the human body. Fever can stimulate the phagocytic function of the reticuloendothelial system, form antibodies, increase the activity of white blood cells, and detoxify the liver. However, high fever can cause metabolic disorders and dysfunction of various systems in the body. Children's nervous system is not fully developed, and they are prone to convulsions when they have a fever, and brain cells may be damaged, resulting in adverse consequences. Therefore, for children with fever, in addition to treating the cause, e...

AI Technical Summary

Problems solved by technology

Oral administration is absorbed quickly and completely, but its adverse reactions include skin rash, drug fever and mucosal damage, which can cause liver and kidney damage, and overdose may cause toxic reactions

The main component of Tylenol solution is acetaminophen, which has been widely used in children with cold and fever, but its disadvantage is that the duration of fever reduction is short (about 3 to 4 hours), and excessive use can cause side effects such as liver damage

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