Sharp type biological film capable of improving fracture healing

Abstract

The invention provides a sharp type biological film capable of improving fracture healing. The sharp type biological film comprises an elastic layer and a medicine layer from inside to outside, wherein the elastic layer is a dense and degradable or absorbable biological film; the medicine layer is a porous loose material which has good biocompatibility with bones of human bodies, is degradable ornon-degradable and is absorbable or non-absorbable; a medicine which has a promotion effect on the fracture healing is also packaged in the medicine layer; a biological micro-structure film is of a long-strip-shaped folding structure and the section of the biological micro-structure film is V-shaped; an elastic layer is arranged in the biological micro-structure film and the medicine layer is arranged outside the biological micro-structure film; the ratio of the width to the depth of the V-shaped section is 0.5 to 1.5 and the width of the V-shaped section is a gap between surfaces of fracturedbones which are spliced together after a fracture surgery.

Description

technical field [0001] The invention relates to a pointed biofilm for improving fracture healing. Background technique [0002] At present, it is a frontier field of medical research to use a biocomposite film containing growth factors / stem cells to stick to the fracture line to enhance the speed and quality of fracture healing. There are blood vessels and bone cells distributed on the inner surface of the fracture line (anastomosis line), and whether the healing is good depends on the growth of blood vessels and bone cells in the fracture line. The reason why biofilm sticking to the surface of fracture anastomosis can increase the quality of fracture healing is that on the one hand, the drugs encapsulated in the biofilm can promote the growth of blood vessels and bone cells in the fracture anastomosis, and on the other hand, the biological The membrane isolates external muscles and other human tissues from the fracture anastomotic line, and prevents the reaction of human t...

AI Technical Summary

Problems solved by technology

[0004] 1. The biocomposite membrane has a relatively large volume area and a small fracture area, and 2 cannot be effectively fitted and fixed together

[0005] 2. The limitations of the current biocomposite membrane materials and manufacturing process lead to performance indicators such as the degradation rate of the biocomposite membrane and the time for the carried growth factors to release the effective drug concentration (the duration of the effective concentration is the key to the healing quality of the fracture line) Unable to meet clinical needs

Images