144 results about "Healed fractures" patented technology

A fastening device having a bellows made of a material that changes shape when activated by a catalyst, and having a pleated structure that contracts from an extended state to a contracted state upon activation. The shape changing material may be a shape memory metal alloy, shape memory polymer or elastic memory composite. A method of using this fastener provides apposition and compression of abutment surfaces to join together two pieces of material, and is suitable for joining apposing bone surfaces together to heal fractures via the use of orthopedic hardware.

Bio-Inks and methods of using compositions comprising the bio-Inks are disclosed. 3-D tissue repair and regeneration through precise and specific formation of biodegradable tissue scaffolds in a tissue site using the bio-inks are also provided. Specific methylacrylated gelatin hydrogels (MAC) and methacrylated chitosan (MACh) preparations formulated with sucrose, a silicate-containing component (such as laponite), and / or a cross-linking agent (such as a photo-initiator or chemical initiator), as well as powdered preparations of these, are also disclosed. Kits containing these preparations are provided for point-of-care tissue repair in vivo. Superior, more complete (up to 99.85% tissue regeneration within 4 weeks applied in situ), and rapid in situ tissue repair and bone formation are also demonstrated.

A pump to deliver bone-growth factors to a carrier matrix within a patient. Pump can be internal or external. With external pumps, additional amounts of the same growth factor may be added, or the bioactive agent may be changed during the course of treatment. An external pump permits the use of cells to promote bone growth. The pump can have several reservoirs and the pump can itself be received in the carrier matrix with an outlet tube or other structure to defuse the growth factors into the carrier matrix. The pump protocol can be used for slow-to-heal fractures, such as closed fractures, and can be used for slow-to-heal patients.

A device and method for stabilizing a broken bone while it heals is disclosed. The device is preferably a metal rod that has a threaded portion. The device is positioned into a bone, such as a metacarpal bone, by forming an opening in the bone suitable for receiving the device, and inserting it into the opening wherein the threaded portion retains the device in position.

A method and apparatus are disclosed for treating bone fractures by the application of intermittent pneumatic compression. The period of compression is sufficient to induce venous stasis at the fracture site. The period of recovery can be about half the period of compression. The applied pressure can be in the range os about 25–60 mmHg.

The invention discloses a digitized design and 3D printing method for an individualized ankle fracture brace. The method comprises the following steps of (1) acquisition of limb laser three-dimensional scanning point cloud data; (2) packaging, smoothing and thickening treatment of the point cloud data; (3) brace hollowing out, button connecting and lockable characteristic design; and (4) 3D printing of the brace. The individualized ankle fracture brace has the following advantages that (1) compared with a plaster bandage, experience and technical requirements for a producer are relatively lowered; (2) suffering of a patient for repeated changing of plaster in the treatment process is relieved; (3) data are precisely extracted according to different physical characteristics and damage situations of injured limbs of patients by use of a 3D laser scanner; (4) the brace can be manufactured by adoption of materials better than plaster in transmissivity, and dynamic X-ray observation of fracture healing situations is facilitated; and (5) in the manufacturing process, a model is hollowed out, so that the brace is made lighter in weight, the air permeability is good, the comfort degree is high, and higher patient compliance is achieved compared with the massive plaster.

The invention relates to a bone grafting device for tubular bone defect healing, and belongs to the technical field of orthopedic medical devices. The bone grafting device is used for grafting tubular bones to promote the healing of the tubular bones, and comprises an outer sleeve, an inner sleeve and a connecting rod, wherein the inner diameter of the outer sleeve is matched with the outer diameter of the two ends of a tubular bone defect part required for bone grafting, and the inner sleeve is positioned in the outer sleeve; the connecting rod is inserted in the inner sleeve, and the diameter of the connecting rod is matched with the inner diameter of the inner sleeve; and the length of the connecting rod is greater than that of the inner sleeve, and the inner sleeve and the outer sleeve are made of biodegradable magnesium alloy. In the bone grafting device, the connecting rod in the inner sleeve can firmly connect the two ends of a defective tubular bone, a high-quality autologous cancellous bone is filled between the inner sleeve and the outer sleeve to simultaneously play roles of bone grafting and reinforced fixing, and the biodegradable magnesium alloy has a function of inducing bone formation, thereby the fracture healing is promoted. The bone grafting device has the advantages of firm bone grafting, high intensity, early ambulation for patients, and good clinical effect.

The invention provides a fractured end micro-movement and blood supply based fracture healing simulation system, relating to the field of biomedical engineering. The system is used for predicting a complicated process of fracture healing and exploring undetermined mechanisms in fracture healing. The system comprises a fracture healing simulation sub-system, an input module and a display module. The fracture healing simulation sub-system (1) comprises a geometry modeling module, a grid partition module, an environment initialization module, a biomechanical calculation module and a biological environment module. The biological environment module is used for creating a biochemical environment of callus in fracture healing so as to finish tissue differentiation in the callus. According to the system, blood supply is used as a dynamic variable and is introduced to the fracture healing simulation system, so that the fracture healing process can be simulated more accurately. The system can perform experiment simulation repeatedly, thereby helping to find out the best fractured end micro-movement value and the impact of blood on fracture healing.

A fastening device having a bellows-like or accordion-like structure made of a material that changes shape when activated by a catalyst, and having pleated or foldable zigzag elements that contract from an extended state to a contracted state upon activation. These elements are formed from zig and zag segments of various shapes. The shape changing material may be a shape memory metal alloy, shape memory polymer or elastic memory composite. A method of using this fastener provides apposition and compression of abutment surfaces to join together two pieces of material, and is suitable for joining apposing bone surfaces together to heal fractures via the use of orthopedic hardware.

The invention discloses a simulation system for long bone fracture healing based on tissue differentiation, and relates to the field of biomedical engineering. The simulation system is used for predicting the complicated process of the fracture healing and searching for the optimal scheme for the fracture healing. The system comprises a fracture area geometric modeling module, a fracture area biomechanics finite element analysis module, a callus unit tissue differentiation module and a program determination judging module. The fracture area geometric modeling module is used for establishing a three-dimensional geometric model of the fracture area; the fracture area biomechanics finite element analysis module is used for conducting finite element analysis on the established three-dimensional geometric model to obtain unit mechanical stimulation; the unit tissue differentiation module is used for simulating tissue differentiation and making the content of each tissue in the unit be updated; the program determination judging module is used for judging whether the program is determined or not. According to the simulation system for the long bone fracture healing based on the tissue differentiation, the fracture area is regarded as a diphasic porous elastic model, the fracture healing process can be more accurately simulated, and the system provides beneficial help for searching for the optimal scheme for the fracture healing.

The invention belongs to the field of medical apparatus and instruments, and relates to a femoral shaft fracture internally fixing instrument, which comprises a lockable steel plate and an aiming assembly of the lockable steel plate, wherein the lockable steel plate comprises a steel plate, a single lock, a linkage lock and a lock nail; the aiming assembly comprises a single lock aiming fixator and a linkage lock aiming fixator; an auxiliary assembly bone nail, a bone nail hole positioning hook and a combined screwdriver. In the femoral shaft fracture internally fixing instrument, an arc which corresponds to the forward physiological curve of a femoral shaft is designed on the steel plate longitudinally; an arc which corresponds to the transverse diameter of the femoral shaft is designed transversely near a bone surface, so that the arc is put in the middle of the fracture position along an arc line of the femoral shaft to contact bones in a limited mode; and the lateral surface is circular arc curved surfaces which are distributed symmetrically and uniformly. The linkage lock strides over a fracture line on the inner side of the femoral shaft, and the single lock is away from the fracture line; and the aiming assembly is used for aiming, fixing, drilling and assembling, and is easy to operate. The femoral shaft has the advantages that the fixation is stable, postoperative additional fixation is avoided, functional exercise can be performed in early stage, and the union of fracture is facilitated, and internal fixtures are convenient to dismantle after union.

The invention discloses an internal fixation therapeutic method of tibial fracture, which comprises the following steps: step one, scanning limb skeletons at a healthy side and a fractural side by a spiral CT (Computed Tomography) respectively; step two, reconstructing and outputting a three-dimensional image of the healthy side limb skeletons and a three-dimensional image of the fractural end skeletons by using MIMICS software; step three, respectively measuring and combining the three-dimensional images of the skeletons at the two sides so as to draw a steel plate drawing required for operation; step four, leading the drawing into PRO / E software of a numerical control centre, and customizing completely individualized internal fixation steel plates, bolt holes and positioning templates after serial technological processes; and step five, implanting the individualized internal fixation steel plates and bolt holes into the fractural skeletons through a minimally invasive surgery by using the positioning templates produced in the step four, thereby finishing the internal fixation operation. The internal fixation therapeutic method has the advantageous effects of capably shortening operative time, capably minimizing periosteal injury around the fractural end, having small operative incision in appearance and enabling fractural patients to heal quickly.

A pump to deliver bone-growth factors to a carrier matrix within a patient. Pump can be internal or external. With external pumps, additional amounts of the same growth factor may be added, or the bioactive agent may be changed during the course of treatment. An external pump permits the use of cells to promote bone growth. The pump can have several reservoirs and the pump can itself be received in the carrier matrix with an outlet tube or other structure to defuse the growth factors into the carrier matrix. The pump protocol can be used for slow-to-heal fractures, such as closed fractures, and can be used for slow-to-heal patients.

The invention relates to a bone repair stent material with traditional Chinese medicine controlled-release function and a preparation method thereof. The bone repair stent material capable of realizing the controlled-release of traditional Chinese medicine comprises bioactive inorganic nano-powder loading the traditional Chinese medicine with the special function, polymer, collagen and excipients, and raw materials constitute the bone repair stent material in the co-blending or the copolymerization way, wherein the traditional Chinese medicine with the special function is the single traditional Chinese medicine with the effects of improving local blood circulation, promoting fracture healing or treating bone diseases or the compound traditional Chinese medicine without tabu in compatibility. The bone repair stent material can maintain the effective medicine concentration in the implantation part within a relatively long time, simultaneously provide an appropriate three-dimensional space and stable mechanical support for the growing of cells and the formation of new bone and better adapt to and meet the clinical requirements.

This device is intended for orthopedic applications, particularly to treat a pars interarticularis fracture. The device is highly specialized to treat a common pars fracture with a uniquely contoured device that stabilizes the inferior fractured element with a generally conforming and non-linear hooked surface then transcribing the pars fracture to rigidly attach to the cortical bone between the facet and pedicle bones while applying compression across the fraction for fracture healing and stabilization.

A surgical fixation pin for use in fractures of bones in arms or other body parts to achieve support of the bone while the fracture heals. The pin is formed of a spring material and includes at opposite ends an angled, rounded front section and a double bent, extracortical section equipped with a fixation eye for receiving a fixation screw for securing the pin to a bone at a fracture site.

A composition for accelerating fracture healing, which comprises a PDE4 inhibitor as an active ingredient, specifically a composition comprising a PDE4 inhibitor and a biocompatible and biodegradable polymer is provided, which composition, when formulated into a form suitable for local administration such as microsphere preparation, can provide a pharmaceutical composition showing an excellent effect in the early healing of bone fracture. The said composition is useful in the healing of refractory fracture of elderly people and diabetic or osteoporosis patients.

The invention discloses an internal fixed parameter optimization treatment individualized modeling method based on a fracture healing process. The method comprises the following steps that a fracturesite is scanned, modeling is performed on a fractured bone; an orthogonal experimental design method is adopted to combine and assemble different internal fixed parameters in a three-dimensional software, the finite element mesh generation is performed on a fractured bone model, a mechanical property value is assigned according to a gray value on the fractured bone of an internal fixation system;the assembly of different screws is carried out, and whole finite element mesh generation is carried out; a mechanical environment simulating the fractured bone is loaded and calculated, a stress on the internal fixation system and a healing result of the fracture are obtained, and then the fracture healing result is evaluated; the screw layout is updated, and the above steps are repeated to perform combined optimization on the screw layout The internal fixed parameter optimization treatment individualized modeling method based on the fracture healing process has the advantages that the errorcaused by manually dividing the cancellous bone and the bone cortex is avoided, and a basis is provided for the combined optimization selection of the internal fixed parameters of a bone fracture plate during the fracture treatment.

The invention discloses a simulation system for simulating a fracture healing process, which relates to the field of biochemical engineering. The simulation system is used for predicting the complex process of fracture healing and providing guidance for doctors in establishing a good surgical program for fracture healing. The system comprises a three-dimensional geometric modeling module, a finite element creation module, a fracture site biomechanical-modeling module, a fracture site cell evolution modeling module, a callus growth modeling module and a display module. Cell concentration and tissue material properties are updated by the fracture site biomechanical-modeling module and the fracture site cell evolution modeling module; the geometric shape of callus is updated by the callus growth modeling module; and the effect of fracture healing is judged by the display module. The simulation system can more accurately simulate the process of fracture healing and repetitively carry out experimental simulation for unlimited times, thus providing help for making the best surgical program for fracture healing.

The invention discloses a flexible intramedullary nail, which pertains to the technical field of orthopedic medical devices and aims at providing a flexible intramedullary nail which can spare secondary operation, eliminate stress shielding, promote fracture healing and has the advantages of simple structure, practicality and low cost. The technical proposal of the invention is that a nail pole of the intramedullary nail consists of a proximal-end nail body, a distal-end nail body and a spring body, wherein, the proximal-end nail body and the distal-end nail body are positioned at both ends of the nail pole respectively and a proximal-end fixed screw hole and a distal-end fixed screw hole are arranged on the two ends; the spring body is arranged in the middle of the nail pole and both ends of the spring body are tightly connected with the proximal-end nail body and the distal-end nail body respectively; the length and quantity of the spring body can be adjusted according to the characteristics of a long bone and the diameter of the spring body can be 2mm to 6mm and can be adjusted according to the requirements of fracture fixing. The flexible intramedullary nail has simple structure and innovative design, resolves the problems of eliminating stress shielding, promoting fracture healing, avoiding secondary operation, and the like after the intrameduallary nail is put in the body, and also has the advantages of simple structure, practicality and low cost.

The present invention relates to a tail filament intramedullary nail and its implantation and taking-out method. Said intramedullary nail is made into the form of column, its tail end is equipped with nail tail cap, and is characterized by that the nail tail cap is connected with tail filament, and the tail end of said tail filament is connected with a metal marked body. The implantation method includes the steps of cutting implantation hole, implanting and fixing intramedullary nail and suturing implantation hole; and the taking-out method includes the steps: cutting taking-out hole, removing fixing nail of intramedullary nail and suturing the taking-out hole.

The invention provides a method of enhancing bone fracture healing involving administering a sclerostin inhibitor. In one aspect, the invention includes use of a therapeutically effective amount of sclerostin binding agent to treat a bone fracture, wherein one or more administrations of the sclerostin binding agent are administered over a treatment period lasting at least two weeks and beginning within two weeks of the fracture.

An expandable intra-medullary nail comprises a nail body and a central rod arranged inside the nail body. The nail body is a hollow tube. The tube walls of the trunk and the far end of the nail body are provided with three or more than three expandable slots lengthways. The far end of the central rod is provided with an expandable head. The near end of the central rod is provided with a screw thread type axial tow attachment. The near end of the nail body is provided with a fixed structure which is a lock nail hole which is arranged at the near end of the nail body and is equipped with a lock nail. The present invention is characterized in that the lock nail is formed by a stainless steel nail body and degradable biological active material wrapped at the outside of the nail body, or the lock nail is made from the degradable biological active material, or the hole wall of the lock nail hole is provided with a layer of degradable biological active material. Compared with the prior art, as the stress simulation can be provided for the middle and later period of the fracture healing and the provided stress simulation is strengthened gradually, the nail of the present invention has the advantages of being good for the porosis at the early period of the fracture, being good for promoting the rebuilding and the cicatrization of bone during the medium and later periods of the fracture and improving the fracture cicatrization effect further.

An acetabulum posterior wall angle locking anatomic bone plate pertains to the technical field of surgical medical devices. The invention provides the acetabulum posterior wall angle locking anatomic bone plate which has small surgical incision, safe and reliable fixation and is conductive to the healing of fracture. The invention includes a plate body which is provided with screw holes, the screw holes are two rows of oblique holes, which are respectively arranged along one side of the plate body which is opposite to the edge of the acetabulum and the opposite side, the oblique included angle Alpha of the central line of the screw holes which are arranged at the one side of the plate body which is opposite to the edge of the acetabulum and the plate surface is 30 degrees to 45 degrees, and the oblique included angle Beta of the central line of the screw holes at the opposite side and the plate surface is 30 degrees to 60 degrees. The invention can make use of the self-shape to ensure the fixation of fracture to be most close to the normal structure after the reduction and fixation of the fracture. The invention has the integrity and the stability which are not possessed by the combined usage of a plurality of bone plates. The invention can reduce surgical incision, reduce the dissection of soft tissues, have less oppression on the periosteum and be more conductive to the healing of fracture. The placement and the removal are easy, and the cost is low. When a screw is screwed, the rod part of the screw can accurately avoid the acetabulum.

The invention relates to a fracture external fixing frame and particularly relates to a fracture external fixing frame with an adjustable axial pressure among bone blocks, belonging to external fixation instruments for fracture treatment. According to the fracture external fixing frame, the problem that the space among fractured blocks usually cannot be properly pressurized when fracture is steadily fixed by virtue of an existing fixing instrument is solved. The fracture external fixing frame is characterized in that a frame rod is segmented, and one or two ends of each segment is / are providedwith plugs or interfaces; spring devices (including one or more of metal springs, gas springs and elastic matter pads) are arranged in the plugs or the interfaces and are spliced to form connecting devices for adjusting the axial pressure among the bone blocks, and the frame rod segments can form an integrated combined frame rod by the connecting devices. By adjusting the elastic forces of the whole spring devices, the action forces of the connecting devices on two frame rod segments on two sides in the long-axis direction are changed, and therefore, the axial pressure among the bone blocks is adjusted. The fracture external fixing frame is applied to fracture fixation, and when the fracture is steadily fixed, excessive stress shielding can be avoided, and the axial pressure among the bone blocks can be flexibly quantized, adjusted and controlled into a proper level required by fracture healing, so that fracture healing is promoted.

The invention discloses a percutaneous bone grafting apparatus, which belongs to an apparatus for grafting a bone in an orthopedic operation. The percutaneous bone grafting apparatus comprises a bone grafting sleeve, a soft tissue separation cone and a drive-in device; a body of the bone grafting sleeve has a hollow structure, one end of the bone grafting sleeve is provided with a feeding hole, the sleeve wall above the feeding hole is trumpet-shaped, and the sleeve wall under the feeding hole is groove-shaped; a body of the soft tissue separation cone has a hollow structure, the head of the soft tissue separation cone is of a blunt circle, and the tail is provided with a conical cap; and a drive-in device body has a T-shaped structure, the head of the drive-in device body is provided with a propulsion platform, and the tail is provided with a drive-in platform. Three apparatuses form a set; the apparatus is combined and used with a Kirschner wire and closed reset inner fixing technology; and under the guide of the Kirschner wire, a hollow soft tissue separator is guided into the bone grafting sleeve, and a bone grafting material is pushed to a destination bone grafting area by using a handle so as to achieve the purpose of percutaneous bone grafting. The percutaneous bone grafting apparatus protects blood circulation around fracture, promotes fracture healing, and can effectively repair bone defects, enhance the bone grafting effect and accelerate limb recovery of patients. The apparatus has a simple structure, is convenient to use, and realizes the purpose of closed bone grafting.

The invention discloses a static and dynamic exchange-type thighbone interlocking intramedullary nail, which comprises a nail main body. A static hole and a first sliding locking hole are arranged on the coronal surface of the far end of the nail main body. A second sliding locking hole is arranged on the sagittal surface of the far end of the nail main body. The first sliding locking hole and the second sliding locking hole are long holes. The static hole is arranged at the far end of the first sliding locking hole and the second sliding locking hole and is arranged at the end part of the far end of the nail main body. Due to the static and dynamic exchange-type thighbone interlocking intramedullary nail, according to the actual situation of fracture healing, early-stage static fixation can be realized, a far-end static locking nail can be taken out to implement dynamic fixation if a fracture is not well healed, static fixation is realized after the first sliding locking hole is in place, a sliding locking nail in place is taken out if the fracture is not healed ideally, dynamic fixation is implemented through a second sliding locking nail, then static fixation is achieved, controllable adjustment of repetitive dynamic and static exchange fixation can be realized and the fracture healing is better promoted.

A bone fastener or an orthopedic implant that resides within the bone after orthopedic surgery has a threaded and / or unthreaded shaft, said shaft has a hollow portion and a solid portion. The hollow portion may have a structure that enhances tissue growth and may also hold materials that enhance tissue growth. The hollow portion may also hold materials to treat diseases and / or promote bone fracture healing.