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Simulation system for long bone fracture healing based on tissue differentiation
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A technology of fracture healing and simulation system, applied in the field of biomedical engineering, to save costs, save time, and improve the success rate of surgery
Inactive Publication Date: 2017-05-31
HARBIN UNIV OF SCI & TECH
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[0008] The purpose of the present invention is to solve the shortcomings that the existing fracture healing simulation cannot comprehensively simulate the influence of mechanical factors and biological factors on the fracture healing process, and the material setting of the biomechanical model of fracture healing is too simplified, and proposes a method based on tissue differentiation. Long bone fracture healing simulation system
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specific Embodiment approach 1
[0034] Specific implementation mode one: as figure 1 As shown, a long bone fracture healing simulation system based on tissue differentiation described in this embodiment includes:
[0035] Fracture area geometric modeling module 1, fracture area biomechanical finite element analysis module 2, callus unit tissue differentiation module 3, program termination judgment module 4;
[0036] The geometric modeling module 1 of the fracture area is used to establish a three-dimensional surface geometric model of the fracture site after image preprocessing according to the imported two-dimensional tomographic image data;
[0037] Fracture area biomechanical finite element analysis module 2 is used to mesh the established fracture area model, apply external loads and set boundary conditions;
[0038] Fracture area biomechanical finite element analysis module 2 is also used for setting the initial fracture area environment;
[0039] Fracture area biomechanical finite element analysis mo...
specific Embodiment approach 2
[0042] Specific implementation mode two: as Figure 1-9 As shown, in this embodiment, the specific process of the geometric modeling module 1 of the fracture area to realize its function is as follows:
[0043] Using the segmentation-based 3D medical image surface reconstructionalgorithm to reconstruct the 3D surface of the image, and obtain the 3D surface geometric model through the process of threshold screening, interactive segmentation and 3D reconstruction;
[0044] The image is obtained by imaging equipment CT, and the data storage format is DICOM.
[0045] Other components and connections are the same as those in the first embodiment.
specific Embodiment approach 3
[0046] Specific implementation mode three: as Figure 1-9 As shown, in this embodiment, the specific process of the biomechanical finite element analysis module 2 in the fracture area to realize its function is as follows:
[0047] 1) Mesh the three-dimensional surface geometric model of the fracture area, discretize the continuous geometric model, and obtain the finite element model of the fracture area;
[0048] The meshing includes two steps of surface meshing and volume meshing; the surface meshing process is used to optimize the three-dimensional surface model, including: surface model optimization, smoothing, repairing loopholes; surface model optimization It is realized by reducing the triangular surface of the surface model. This process only needs to merge two adjacent vertices into a new vertex, and continue the original topological relationship; in the process of smoothing, the three-dimensional surface network In the process of repairing the holes, the holes in th...
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Abstract
The invention discloses a simulationsystem for long bone fracture healing based on tissue differentiation, and relates to the field of biomedical engineering. The simulationsystem is used for predicting the complicated process of the fracture healing and searching for the optimal scheme for the fracture healing. The system comprises a fracture area geometric modeling module, a fracture area biomechanics finite element analysis module, a callus unit tissue differentiation module and a program determination judging module. The fracture area geometric modeling module is used for establishing a three-dimensional geometric model of the fracture area; the fracture area biomechanics finite element analysis module is used for conducting finite element analysis on the established three-dimensional geometric model to obtain unit mechanical stimulation; the unit tissue differentiation module is used for simulating tissue differentiation and making the content of each tissue in the unit be updated; the program determination judging module is used for judging whether the program is determined or not. According to the simulation system for the long bone fracture healing based on the tissue differentiation, the fracture area is regarded as a diphasic porous elastic model, the fracture healing process can be more accurately simulated, and the system provides beneficial help for searching for the optimal scheme for the fracture healing.
Description
technical field [0001] The invention relates to the field of biomedical engineering, in particular to a long bone fracture healing simulation system based on tissue differentiation. Background technique [0002] Fracture is a common trauma. The high incidence of fracture makes the study of fracture mechanism and promotion of healing particularly urgent. Once a fracture occurs, unlike other tissue damage repairs, the fracture is not connected by fibrous connective tissue, but by bone tissue. Fully regenerated. However, not all fractures heal completely, and sometimes delayed union or even nonunion occurs. Delayed union or nonunion of fractures can cause pain and dysfunction in the affected limb, leading to unemployment of the patient, which causes a great social and economic burden. Therefore, although the research on fracture healing has been receiving much attention, there are still 5% to 10% of fractures with delayed union or even nonunion due to various reasons. [000...
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