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Gradient distribution-based non-rigid medical image registration method

A gradient distribution, medical image technology, applied in the registration field of non-rigid medical images, can solve the problem of not considering the gradient, low registration error and so on

Pending Publication Date: 2018-05-18
ZHONGYUAN ENGINEERING COLLEGE
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Problems solved by technology

The registration experiments of preoperative brain magnetic resonance images and intraoperative ultrasound images have confirmed that this method can obtain lower registration errors. However, this method only uses the direction information of the gradient and does not consider the gradient mode

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Embodiment Construction

[0086] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0087] The invention provides a non-rigid body medical image registration method based on gradient distribution. First, the normalized mutual information similarity measure is studied, and the joint probability distribution of two images is estimated by using the Parzen window based on B-spline function, and the normalized The mutual information is used to measure the similarity between the reference image and the floating image; secondly, the gradient of the r...

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Abstract

The invention discloses a gradient distribution-based non-rigid medical image registration method. The steps are as follows: (S1) a normalized mutual information similarity measure is constructed; (S2) a gradient distribution distance is constructed; (S3) a non-rigid registration model is created; (S4) the registration model is solved. The gradient distribution-based non-rigid medical image registration method not only utilizes the gray distribution characteristics of images to be registered, but also takes the gradient distribution information of the medical images into consideration, thus effectively fulfilling the non-rigid registration of the medical images. Moreover, preprocessing, such as feature extraction and splitting, does not need to be carried out on the images to be registered, but the joint probability distribution of gray values of two images is utilized to calculate normalized mutual information between the images to be registered, the gradient distribution-based non-rigid medical image registration method also has a good registration effect on medical images with great grayscale difference, and adaptivity and robustness are high.

Description

technical field [0001] The invention relates to a registration method of a non-rigid body medical image, in particular to a non-rigid body registration method for a medical image by using a gradient distribution distance of an image to be registered and a normalized mutual information similarity measure, and belongs to the field of medical image processing . Background technique [0002] Medical image registration is an important technology in the field of medical image processing, which plays an important role in medical information fusion, tumor growth monitoring, image-guided surgical treatment, and radiotherapy planning. Medical image registration can fuse various complementary information together to provide more reliable information for doctors to diagnose diseases. The rapid development and wide application of microelectronics, computers, and information science have led to the rapid development of medical imaging technology. However, during the imaging process of t...

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Application Information

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IPC IPC(8): G06T7/33
CPCG06T7/344
Inventor 李碧草王贝刘洲峰舒华忠李春雷徐庆伟
Owner ZHONGYUAN ENGINEERING COLLEGE
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