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An Elastic Registration Method Coupled with Respiratory Phases

An elastic registration and time-phase technology, which is applied in the field of medical image registration and positioning verification, can solve problems such as rarely considering dynamic registration, and achieve the effect of improving registration quality

Active Publication Date: 2022-04-01
中科超精(南京)科技有限公司
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AI Technical Summary

Problems solved by technology

Traditional CT image registration mostly considers the static registration between images, but seldom considers the dynamic registration between images in the case of respiratory motion control, so it is urgent to provide a new type of coupling respiratory phase Elastic registration method to solve the above problems

Method used

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  • An Elastic Registration Method Coupled with Respiratory Phases

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Embodiment Construction

[0014] The preferred embodiments of the present invention will be described in detail below in conjunction with the accompanying drawings, so that the advantages and features of the present invention can be more easily understood by those skilled in the art, so as to define the protection scope of the present invention more clearly.

[0015] see figure 1 , the embodiment of the present invention includes:

[0016] A group of 4D lung CT images of lung cancer patients in free deep breathing mode are used as test cases. The volume of the collected images is 512×512×640, and the resolution is 0.97×0.97×0.5mm 3 . First, collect 4D lung CT images, and record the three-dimensional space coordinates of in vitro markers at the same time; then use the distance correspondence method to establish the relationship between 4D lung CT images and respiratory signals, and analyze the relationship between CT slices at different positions in each phase of 4D CT. Correspondence, by comparing th...

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Abstract

The invention discloses an elastic registration method coupled with respiratory phases, which combines X-ray images and 4D CT images during treatment, extracts respiratory signals based on X-ray perspective imaging, and uses 4D CT images in different phases to correspond to X-ray perspective Image, the respiratory phase information is coupled to the elastic registration before treatment and during treatment, the registration result is updated in real time according to the similarity measure, and the neighborhood gray scale and registration are simultaneously adjusted through pyramid multi-resolution registration The range of images reduces the registration range, and the elastic registration results can be obtained more quickly and accurately, so that the elastic registration can be fast and excellent, and the registration quality of medical images can be further improved.

Description

technical field [0001] The invention relates to the field of medical image registration and positioning verification in tumor radiotherapy and surgical navigation, in particular to an elastic registration method coupled with respiratory phase. Background technique [0002] For thoracic and abdominal tumors such as lung cancer, liver cancer, pancreatic cancer, etc., the tumor movement will be affected by respiratory movement and cause position deviation. Especially during the treatment process, the relative position between the tumor and the surrounding normal tissues and organs will change to a certain extent. At the same time, there are still errors such as deformation of anatomical structures, which seriously affect the dose distribution in the human body, reduce the therapeutic effect, and even cause various radiotherapy complications. Medical image registration is the core of tumor target delineation and setup verification before radiotherapy. According to the spatial t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T7/32
CPCG06T7/32G06T2207/30061G06T2207/30096G06T2207/20016G06T2207/10076
Inventor 不公告发明人
Owner 中科超精(南京)科技有限公司
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