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Microneedle structure for efficient skin perforation

A technology of microneedles and needle tips, applied in the field of dissolvable microneedles

Active Publication Date: 2018-12-21
LG HOUSEHOLD & HEALTH CARE LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The characteristic of microneedles is that they do not feel pain and do not bleed even when inserted into the skin. However, it is very difficult to manufacture microneedles that do not break or bend while maintaining such characteristics.

Method used

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  • Microneedle structure for efficient skin perforation
  • Microneedle structure for efficient skin perforation
  • Microneedle structure for efficient skin perforation

Examples

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Embodiment Construction

[0093] Hereinafter, in order to facilitate understanding of the present invention, examples and the like are given and described in detail. However, the embodiments according to the present invention can be modified into other various forms, and it should not be construed that the scope of the present invention is limited to the following embodiments. The embodiments of the present invention are provided in order to more fully explain the present invention to those having an average level of knowledge in the art.

[0094] Fabrication of Dissolvable Microneedles

[0095] As shown in Table 1 below, microneedles were fabricated. In this specification, unless otherwise specified, the content of the composition is expressed in % by weight.

[0096] HA (Hyaluronic acid), Na-CMC (Sodium carboxymethyl cellulose), and trehalose (Trehalose) were dissolved in purified water, and then glycerin (Glycerin), HCO-40, and niacinamide (Niacinamide) were added to prepare a solution. The pro...

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Abstract

The present invention relates to a soluble microneedle and, more particularly, to a microneedle and a microneedle patch comprising the same, wherein the microneedle is used to perforate skin, and themicroneedle, when inserted through the perforated skin, is then dissolved, thereby administering the target material from inside the microneedle into the skin. The microneedle according to the presentinvention, when used, has appropriate levels of mechanical strength, viscosity, and hardness and can be easily inserted into skin without undergoing shape change, for example, bending or breaking, thereby enabling efficient skin perforation. In addition, as the microneedle according to the present invention is dissolved through the perforated skin, the target material penetrates the skin at an excellent ratio. Accordingly, there is no need to apply strong force, and the target material can be effectively delivered into the skin regardless of which part of the microneedle contains the target material.

Description

technical field [0001] This application claims priority based on Korean Patent Application No. 10-2016-0041577 filed on April 5, 2016, and all the contents disclosed in the specification and drawings of this application are incorporated into this application. [0002] The present invention relates to a dissolvable microneedle. After the skin is perforated by the microneedle, when the microneedle is inserted through the perforated skin, the microneedle dissolves, thereby injecting the target substance in the microneedle into the skin. Background technique [0003] Various methods for efficiently transdermally administering a target substance have been studied. However, the skin surface layer has a barrier function to prevent impurities from entering the body, so it is difficult to absorb a sufficient amount of the target substance to exert the desired effect, and it is very difficult to accurately supply the target substance to a designated part of the skin surface layer. In...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M37/00A61L27/20A61L27/58A61L27/54A61F13/02A61K9/00A61K9/70
CPCA61K9/0021A61K9/7023A61K47/36A61K47/38A61K47/26A61K47/10A61K31/455A61M37/0015A61M2037/0023A61M2037/0061A61M2037/0046A61L27/20A61L27/54A61L27/58A61K9/00A61F13/02A61K9/70A61M37/00A61L2300/232A61L2300/41A61F13/0259A61L31/042
Inventor 沈愚先黄英暋姜来圭
Owner LG HOUSEHOLD & HEALTH CARE LTD
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