A pharmaceutical composition for treating gout and a preparation method thereof

A technology of composition and medicine, applied in the field of medical invention, can solve the problem that there is no good way to treat gout

Inactive Publication Date: 2019-01-11
威宁县荞源食品加工厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there is no good method for treating gout. In order to solve this problem, the inventor has developed a new drug

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Prescription: Astragalus 10g, Ophiopogon japonicus 15g, Houttuynia cordata 10g, Rouge radish 10g, Atractylodes macrocephala 10g, Poria cocos 15g.

[0026] Preparation:

[0027] 1) Grind Ophiopogon japonicus, Houttuynia cordata, Rouge radish, and Salvia miltiorrhiza into fine powder for later use;

[0028] 2) Decoct Astragalus, Atractylodes Rhizoma Atractylodes Rhizome, and Poria cocos with 3 times the amount of water twice, 1 hour each time, combine the decoctions, let stand, filter, concentrate the filtrate to a clear paste, wait for cooling, add 2 times the amount of 75% ethanol to make Precipitate, take the supernatant, add 2 times the amount of 75% ethanol to the precipitate, stir, let it stand for 12 hours, take the supernatant, combine the alcohol solution, recover the ethanol under reduced pressure and concentrate it into an extract, dry the extract, and crush it into fine powder; add starch accounting for 1 / 5 of the weight of the mixed fine powder, and pack int...

Embodiment 2

[0030] Prescription: Astragalus 50g, Ophiopogon japonicus 60g, Houttuynia cordata 35g, Rouge radish 30g, Atractylodes macrocephala 40g, Poria cocos 55g.

[0031] Preparation:

[0032] Add astragalus, Ophiopogon japonicus, Houttuynia cordata, rouge radish, Atractylodes macrocephala, Poria cocos with 3 times the amount of water and decoct twice, 1 hour each time, combine the decoctions, let stand, filter, concentrate the filtrate to a clear paste, wait for cooling, Add 2 times the amount of 75% ethanol to precipitate, take the supernatant, add 3 times the amount of 75% ethanol to the precipitate, stir, let it stand for 14 hours, take the supernatant, combine the alcohol solution, recover the ethanol under reduced pressure and concentrate it into an extract. Dried the extract, crushed into fine powder; added pharmaceutically acceptable carrier or diluent and mixed evenly to make a preparation.

Embodiment 3

[0034] Prescription: Astragalus 15g, Ophiopogon japonicus 20g, Houttuynia cordata 12g, Rouge radish 12g, Atractylodes macrocephala 13g, Poria cocos 20g.

[0035] Preparation:

[0036] Add astragalus, Ophiopogon japonicus, Houttuynia cordata, rouge radish, Atractylodes macrocephala, Poria cocos with 3 times the amount of water and decoct twice, 1 hour each time, combine the decoctions, let stand, filter, concentrate the filtrate to a clear paste, wait for cooling, Add 2 times the amount of 75% ethanol to precipitate, take the supernatant, add 3 times the amount of 75% ethanol to the precipitate, stir, let it stand for 14 hours, take the supernatant, combine the alcohol solution, recover the ethanol under reduced pressure and concentrate it into an extract. Dried the extract, crushed into fine powder; added pharmaceutically acceptable carrier or diluent and mixed evenly to make a preparation.

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PUM

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Abstract

A pharmaceutical composition for treating gout and a preparation method thereof are provided. The pharmaceutical composition for treating gout is prepared from astragalus root, radix Ophiopogonis, herba Houttuyniae, carmine radish, Atractylodis rhizoma, Poria through ethanol extraction, water decoction, etc. As observed in a clinical trial, that pharmaceutical composition of the invention can obviously improve the attack frequency of gout patients, has remarkable curative effect of prevent urination frequency, and has an effective rate of 80%.

Description

technical field [0001] The invention relates to the field of medical inventions, in particular to a pharmaceutical composition for treating gout and a preparation method thereof. Background technique [0002] Gout is a crystal-associated arthropathy caused by the deposition of monosodium urate (MSU), which is directly related to hyperuricemia caused by purine metabolic disorders and / or decreased uric acid excretion, specifically referring to acute characteristic Arthritis and chronic tophi diseases mainly include acute onset arthritis, tophi formation, tophi chronic arthritis, urate nephropathy and uric acid urolithiasis. In severe cases, joint disability and renal insufficiency may occur. Gout is often accompanied by abdominal obesity, hyperlipidemia, hypertension, type 2 diabetes and cardiovascular disease. The most important biochemical basis of gout is hyperuricemia. A normal adult produces about 750 mg of uric acid per day, of which 80% is endogenous and 20% is exogen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P19/06
CPCA61K36/481A61K36/076A61K36/284A61K36/31A61K36/78A61K36/8968A61K2236/331A61K2236/39A61K2236/53A61P19/06A61K2300/00
Inventor 孙吉孙翔孙学武戴永菊
Owner 威宁县荞源食品加工厂
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