Systems and methods for analysis of insulin regimen adherence data
A technology for insulin and regimens, applied in the field of systems and methods for analyzing insulin regimen compliance data, capable of solving problems such as inputting wrong data, users being unable to answer, and timing being easily affected by uncertainty
Inactive Publication Date: 2019-02-05
NOVO NORDISK AS
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Problems solved by technology
WO 2010 / 149388 does not address the problem of measuring adherence to metabolic activity in relation to a prescription regimen in situations where the user forgets to make an input when prompted, the user fails to answer when prompted, or the user responds for some reason. enters erroneous data into memory when prompted for various reasons; and it does not address the problem of directly monitoring compliance based on metabolic activities that the user has participated in and not only intends to participate in, or has engaged in not so long ago
In other words, the timing between the user input activity and the metabolic activity on monitoring compliance is subject to uncertainty
Method used
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example 1
[0180] Example 1: Using autonomic glucose measurements to identify metabolic events and characterize them as insulin prescriptions regimen adherence or insulin regimen nonadherence . Block 402 above describes how the second data set 240 including the plurality of glucose measurements is obtained autonomously in some embodiments. In this example, in addition to autonomic glucose measurements, insulin administration events are obtained in the form of insulin dose records from one or more insulin pens and / or pumps 104 used by the subject to apply the prescribed insulin regimen. These insulin dose records may exist in any format, and in fact may be spread across multiple files or data structures. Thus, in some embodiments, the present disclosure takes advantage of recent advances in insulin administration pens, which have become "smart" in the sense that they can remember the timing and amount of insulin doses administered in the past. An example of such an insulin pen 104 is...
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Systems and methods are provided for monitoring adherence to an insulin medicament dosage regimen for a subject. A data set comprising a plurality of metabolic events the subject engaged in within a period of time is obtained. Each respective metabolic event comprises a timestamp of the event and a characterization that is one of insulin regimen adherent and insulin regimen nonadherent. A plurality of primary adherence values is calculated, each respective adherence value representing a corresponding time window in a plurality of time windows within the period of time. Each time window is of asame first fixed duration. Each respective adherence value is computed by dividing a number of insulin regimen adherent events by a total number of events that have timestamps in the time window corresponding to the respective adherence value. The adherence values across the period of time are communicated thereby monitoring adherence to the insulin regimen.
Description
technical field [0001] The present disclosure generally relates to systems and methods for assisting patients and healthcare practitioners in monitoring compliance with a prescribed insulin dosage regimen and for advising which improvements in regimen compliance will beneficially affect glucose levels. Background technique [0002] Type 2 diabetes is characterized by a progressive disturbance of normal physiological insulin secretion. In healthy individuals, basal insulin secretion by pancreatic beta cells occurs continuously to maintain steady glucose levels over extended periods between meals. There is also prandial secretion in healthy individuals, where insulin is released rapidly in an initial first phase spike in response to a meal, followed by a sustained insulin secretion that returns to basal levels after 2-3 hours. [0003] Insulin is a hormone that binds to the insulin receptor to lower blood sugar by promoting the cellular uptake of glucose, amino acids and fatt...
Claims
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IPC IPC(8): G16H20/13G16H50/20A61B5/145
CPCG16H50/20G16H20/10G16H20/17A61B5/14532A61B5/4839G16H40/63A61B5/0004A61B5/4833A61B5/4866A61B5/7282A61B5/742
InventorH.本特松T.B.阿拉多蒂尔P.布罗克梅尔
OwnerNOVO NORDISK AS