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Systems and methods for analysis of insulin regimen adherence data

A technology for insulin and regimens, applied in the field of systems and methods for analyzing insulin regimen compliance data, capable of solving problems such as timing being easily affected by uncertainties

Inactive Publication Date: 2019-03-01
NOVO NORDISK AS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In other words, the timing between the user input activity and the metabolic activity associated with monitoring compliance with the prescribed regimen is subject to uncertainty

Method used

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  • Systems and methods for analysis of insulin regimen adherence data
  • Systems and methods for analysis of insulin regimen adherence data
  • Systems and methods for analysis of insulin regimen adherence data

Examples

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example 1

[0152] Example 1: Using Autonomic Glucose Measurements to Identify and Classify Metabolic Events as Insulin Regimen Dependent From or non-adherence to insulin regimen . Block 402 above describes how the second data set 240 including the plurality of glucose measurements is obtained autonomously in some embodiments. In this example, in addition to autonomic glucose measurements, insulin administration events are obtained in the form of insulin medication records from one or more insulin pens and / or pumps 104 used by the subject to apply the prescribed insulin regimen. These insulin medication records may exist in any format and in fact may be spread across multiple files or data structures. As such, in some embodiments, the present disclosure takes advantage of recent advances in insulin administration pens, which have become "smart" in the sense that they can remember the timing and amount of insulin medication administered in the past. One example of such an insulin pen ...

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Abstract

System and methods are disclosed for monitoring adherence to a prescribed insulin regimen for a subject. A data set comprising a plurality of metabolic events the subject engaged is obtained. Each metabolic event comprises a timestamp of the event and a first classification that is one of insulin regimen adherent and nonadherent. Each respective metabolic event is then further classified using a second classification, based upon the timestamp of the metabolic event. The second classification has a temporal periodicity represented by a plurality of periodic elements. Metabolic events are binnedon the basis of the second classification thereby obtaining a plurality of subsets of the metabolic events, each subset for a different periodic element. For each respective subset, a respective representation of adherence to the insulin regimen is communicated, the representation of adherence being collectively based upon the first classification of metabolic events in the respective subset.

Description

technical field [0001] The present disclosure relates generally to methods for assisting patients and healthcare practitioners in identifying periodic non-compliance with a prescribed insulin drug dosing regimen as a basis for determining what improvements in regimen compliance will beneficially affect glucose levels systems and methods. Background technique [0002] Type 2 diabetes is characterized by progressive disruption of normal physiological insulin secretion. In healthy individuals, basal insulin secretion by pancreatic beta cells occurs continuously to maintain steady glucose levels over extended periods between meals. And in healthy individuals there is prandial secretion, where insulin is released rapidly in an initial first phase spike in response to a meal, followed by a prolonged insulin secretion that returns to basal levels after 2-3 hours. [0003] Insulin is a hormone that binds to the insulin receptor to lower blood sugar by promoting the cellular uptake...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H20/10G16H20/17G16H50/20A61B5/00A61B5/145
CPCG16H50/20A61B5/0022A61B5/14532G16H20/17G16H40/67G16H50/50G16H10/60G16H50/30G16H20/10
Inventor H.本特松T.B.阿拉多蒂尔P.布罗克梅尔
Owner NOVO NORDISK AS
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