87 results about "Medication administered" patented technology

Dose guidance systems and methods for titrating medication doses are described. The dose guidance system may receive glucose data from a continuous glucose monitor and may receive medication data related to medication administered by the user. The dose guidance system may initialize dose guidance parameters, recommend medication doses, titrate medication doses, and provide alerts based on the glucose data and medication data.

The invention discloses a medicine purchasing behavior data processing method and device, electronic equipment and a storage medium, and relates to the technical field of data management.The method comprises the steps that historical medicine purchasing behavior data of a user is collected; determining a drug use continuous state sequence of the user according to the historical drug purchase behavior data; the historical medicine purchasing behavior data, the context features and the user tags are coded through an attention model, and user behavior time sequence features are obtained; according to the medication continuous state sequence and the user behavior time sequence characteristics, hidden medication state information of the user is determined, and the hidden medication state information at least comprises probability distribution information of the user in various medication states. According to the method and the device, the technical problem that the prediction accuracy of the medication state of the user is low due to the fact that the medication state of the user is predicted mainly depending on physiological monitoring indexes or single behavior rules in the prior art, and the user cannot be accurately reminded to purchase or take medicines in time is solved.

The present invention inter alia relates to an enhanced chimeric CD8 Co-receptor, wherein the CD8 Co-receptor comprises a polypeptide including at least one functional polypeptide domain or a functional polypeptide motif of a CD8 Co-receptor, and wherein said polypeptide further comprises at least one CD8-derived polypeptide region including a functional polypeptide domain or a functional polypeptide motif of a wildtype human CD8 Co-receptor.The enhanced chimeric CD8 Co-receptor further comprises at least one cytoplasmic polypeptide domain or cytoplasmic polypeptide motif of a tumor necrosis factor receptor superfamily protein, a immunoglobulin superfamily (IgSF) protein, and / or an ITAM-associated receptor. The present invention also relates to a nucleic acid encoding the enhanced chimeric CD8 Co-receptor, a vector comprising the nuclear acid encoding for the enhanced chimeric human CD8 Co-receptor, as well as to isolated T-cells being transduced, transformed or transfected with the nucleic acid or the with the vector, and to isolated T-cells being transduced, transformed or transfected to express the enhanced chimeric CD8 Co-receptor as well as to engineered T-cells expressing the chimeric CD8 Co-receptor. The invention further relates to a kit for preparing the isolated T-cells of the present invention, as well as to a pharmaceutical composition comprising the T-cells. The invention also relates to a method for preparing a T-cell for immunotherapy, and to a method for treating a patient having a disease comprising administering the pharmaceutical composition.

A product provision system, a product provision processing device, and a program are provided that prevent health damage caused by the overdose of medicines. [Solution] When a user selects to purchase a drug package containing multiple drugs, the amount of a specific abuse-preventing ingredient contained in the drug package selected for purchase is calculated. Also, based on the calculated amount of the specific ingredient and drug-taking history information on the abuse-preventing ingredient contained in the drug package previously provided to the user, an estimated drug-taking amount is calculated to estimate the amount of the specific ingredient within a predetermined period. Then, when it is determined that the calculated estimated drug-taking amount exceeds a predetermined upper dose limit, provision of the drug package selected for purchase by the user is discontinued.

The invention provides a medicine box and a medicine taking reminding system. And the medicine box and the reminding system are in data transmission communication with each other. The system may also include a global positioning system, an accelerometer, or both. The cartridge compartment is configured to contain a medicament. The medicine box is provided with a sensor or a sensor array used for detecting the number of medicine in the medicine box. The cartridge processor is configured to generate a data signal related to an amount of medication within the cartridge. The system may generate a medication reminder, such as a reminder regarding supplementation of prescription medication or medication with food. The medicine box can comprise or be connected with a smart phone protection shell, and can also be integrated into a smart watch.

A method for estimating personalized probability of a drug side effect includes identifying a drug taken by a subject, identifying an experience of a side effect, which is produced as the subject takes the drug, and input by the subject, and estimating a probability of the side effect of the subject in relation to the drug, based on the experience of the side effect of the subject, which are executed by a computing device.

The present disclosure relates to fluorinated phenylamino compounds, pharmaceutical compositions thereof, and methods of treating a tumor or cancer selected from the group consisting of plexiform neurofibroma (PN), plexiform neurofibroma associated with neurofibromatosis type 1 (NF1-PN), cutaneous neurofibroma (cNF), pancreatic ductal adenocarcinoma (PDAC), high-grade glioma (HGG), low-grade ovarian cancer, tuberous sclerosis (TSC), Langerhans cell histiocytosis (LCH), brain tumor, and cancer metastasized to the brain of a patient, comprising administering these pharmaceutical compositions to a patient in need thereof.

To provide a clothing-integrated medicine case that enables a user to always carry medicine on his / her person so as to reduce forgetting to take medicine or searching for a place to put it and to reduce the time and effort required to transfer medicine to another bag when going out. [Solution] This device is designed to allow commonly used medications to be carried around by placing them in an inner pouch i inside multiple square-shaped pockets b attached to clothing a. When taking medication, the user looks at the letters written in each square, removes the inner pouch from the pocket, and takes the medication. Since the letters e and f written on the pocket are close to the eyes when it is time to take the medication, the user is less likely to forget to take the medication.

The utility model discloses a medicine box with a reminding function, which comprises a box body, an electronic clock, a loudspeaker, a reminding lamp, a switch and an operation button are arranged on the box body, a control processor and a battery are arranged in the box body, a medicine placing groove is arranged on the box body, a plurality of clamping grooves are uniformly arranged on two sides of the medicine placing groove along the extending direction, and partition plates are inserted in the medicine placing groove through the clamping grooves. A box cover is arranged at the upper end of the medicine containing groove. A business card groove is formed in the back side of the box body; a strip-shaped hole communicated with the interior of the business card groove is formed in the upper part of the business card groove. The medicine containing grooves can be divided into needed storage spaces according to needs, medicine needing to be taken at a time can be placed separately, meanwhile, when medicine is taken, only the medicine in the same medicine containing groove needs to be taken, mistaken taking is avoided, meanwhile, the space utilization rate is higher than that of independent storage, the reminding effect is better, the name card groove is formed, and the medicine containing groove is convenient to use. A paper strip recording the medical history of a patient and the name of the currently taken medicine can be placed in the medicine box.

Techniques are disclosed for defining a homeostatic window for controlling delivery of electrical stimulation therapy to a patient. In one example, a method includes generating and delivering electrical stimulation therapy to tissue of a patient via electrodes. Further, the method includes adjusting a level of a parameter of the electrical stimulation therapy such that a signal of the patient is not less than a lower bound and not greater than an upper bound. The lower bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce one or more symptoms of a disease while the patient was receiving medication for reduction of the one or more symptoms. Further, the upper bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce the one or more symptoms when the patient was not receiving the medication.

The present invention provides a pharmacological wearable cardioverter defibrillation system for conducting cough assisted pharmacological cardioverter defibrillation during onset of a sudden arrhythmia. The system comprises a WCD defibrillator worn by the patient, a drug mix contained either in a reservoir / pump or in an inhaler, and a miniature monitor. The drug mix in the reservoir / pump is equipped with a pump for pumping the drug mix via an indwelling catheter to the coronary sinus while the drug mix in the inhaler is inhaled directly to the lungs. When a sudden arrhythmia is detected by a sensing electrode of WCD, the following steps are carried out: prompting the patient to take the drug mix, prompting the patient to start forceful coughing, and delivering electric shock(s) under either one of the two circumstances that the patient is unable to start coughing or the arrhythmia is not terminated.

The invention provides an intelligent medicine box capable of being connected with intelligent electronic equipment for reminding, comprising a medicine box body which is provided with a plurality of mutually separated accommodating chambers for accommodating medicines; the inductive switch is arranged in the medicine box body and is used for inducting the on-off state of the medicine box body; the intelligent electronic equipment is used for recording and reminding medication information; the communication module is mounted in the medicine box body and is used for synchronizing data with intelligent electronic equipment in real time; the prompt module is installed in the intelligent electronic equipment and used for setting the medicine taking-out state within the time and giving a prompt alarm when the medicine state is not taken out and the medicine box body is not closed after the set time is exceeded; according to the medicine box, the taking-out condition of the medicine in the containing cavity is recognized in a matched mode on the premise that the opening and closing state of the medicine box body is sensed, and the situation that the medicine box body is opened by mistake or mistaken recording is generated when the medicine which is not taken is opened is avoided; and accurate and reliable medication management support is provided.

Methods and systems use a particular medication administered to a patient to identify one or more nutrient deficiencies associated with the particular medication, identify one or more drug-nutrient interactions associated with the particular medication, and / or identify one or more symptoms or side effects associated with the particular medication. Information stored in a database contains one or more of these associations and is used for the identification. The method may then provide one or more nutritional interventions and / or one or more dietary recommendations based on (i) the one or more nutrient deficiencies, (ii) the one or more drug-nutrient interactions, and / or (iii) the one or more symptoms or side effects.

An information transmission system includes a first information processing apparatus disposed in a first facility and a second information processing apparatus disposed in a second facility. The first information processing apparatus includes first circuitry. The first circuitry generates a code image in which a medication-related information group including medication-related information relating to a plurality of individuals taking medication is encoded, and forms the generated code image on a recording medium to be delivered from the first facility to the second facility. The second information processing apparatus includes second circuitry. The second circuitry acquires the medication-related information group from a captured image obtained by capturing an image of the code image on the recording medium delivered from the first facility to the second facility.

The invention provides an intelligent medicine box device with a dose memory function, and relates to the technical field of medical instruments. The intelligent medicine box device with the dose memory function comprises a box body, the upper end of the box body is connected with a box cover through a hinge, a partition plate is arranged in the box body, and the two side walls of the partition plate are fixedly connected to the two inner side walls of the box body respectively. Storage structures are arranged at the positions, close to the edge of one side, of the interior of the box body on the front side and the interior of the box body on the rear side of the partition plate respectively, a protection structure is arranged at the position, close to the upper end, of the center of one inner side wall of the box body, and protection structures are arranged on the inner side walls of the storage structures and the two side walls of the partition plate respectively. By arranging a storage structure, a patient can adjust and process a plurality of indicator lamps on the upper end face of a vertical plate through a small controller according to specified medicine during use, the indicator lamps with the corresponding number are adjusted to be turned on according to different numbers of medicine taken, and the patient with poor memory is recorded and processed.

The present application relates to the field of heart failure risk assessment, in particular to a kind of early screening and hierarchical management system of senile heart failure based on metabolic abnormality.The system first obtains the initial heart failure performance value of the senile patient to be measured according to the blood sodium concentration value of the senile patient to be measured at each time point and the change of blood sodium concentration value in time sequence, according to the difference between the senile patient to be measured and the senile patient to be selected in the drug data information, the difference between the senile patient to be measured and the senile patient to be selected in the blood drug concentration value at each time point and the time difference of the last time taking medicine, the reference senile patient of the senile patient to be measured is screened from all the senile patients to be selected, according to the difference between the senile patient to be measured and the senile patient to be selected in the blood sodium concentration value at each time point, and the initial heart failure performance value of the senile patient to be measured, the heart failure performance of the senile patient to be measured is hierarchically evaluated.The present application can improve the accuracy of screening and hierarchical evaluation of senile heart failure.

The arrhythmia alarm watch facilitating medicine storage relates to the technical field of medical monitoring and comprises a dial plate and a protective cover, a supporting plate is arranged between the two sides of the interior of the dial plate, a fixing cylinder is arranged in the middle of the bottom end of the interior of the dial plate, and a reset spring is arranged at the top of the fixing cylinder. And an operating rod is arranged at the top of the reset spring, a display screen is embedded in the middle end of the top of the operating rod, a bearing is connected to the upper portion of the exterior of the fixing cylinder, and a rotating frame is further connected to the exterior of the bearing. According to the arrhythmia alarm watch convenient for medicine storage, the elastic watchband is worn on the wrist, the processor is used as a control core, the heart rate of a patient is monitored by means of the heart rate sensor tightly attached to the wrist, data are collected and transmitted to the processor, and whether arrhythmia exists or not is analyzed and judged through the processor; when arrhythmia occurs, the voice alarm is triggered, and the voice alarm gives an alarm to remind a patient to take medicine in time.

A pill case and medication reminder system is provided. A pill case and a reminder system are in data transfer communication with one another. The system can also include a global positioning system, an accelerometer, or both. A pill case compartment is configured to hold a medication. The pill case has a sensor or sensor array configured to detect the amount of medication in the pill case. A pill case processor is configured to generate a data signal pertaining to the amount of medication in the pill case. The system can generate medication reminders, for example, pertaining to refilling a subscription or taking medication with food. The pill case can include or connect to a phone case for a smartphone, or can be integrated into a smartwatch.

The invention relates to the field of heart failure risk assessment, in particular to an old-age heart failure early screening and hierarchical management system based on metabolic abnormality. According to the system, an initial heart failure performance value of a to-be-detected elderly patient is obtained according to a blood sodium concentration value of the to-be-detected elderly patient at each time point and the change of the blood sodium concentration value in a time sequence; according to the difference of the medication data information between the to-be-detected elderly patient and the to-be-selected elderly patient, the difference of the blood concentration values of the same medicine at each time point between the to-be-detected elderly patient and the to-be-selected elderly patient, and the time difference when the medicine is taken last time, determining the medication data information of the to-be-detected elderly patient; and screening a reference elderly patient of the to-be-detected elderly patient from all the to-be-selected elderly patients, and performing grading evaluation on the heart failure performance of the to-be-detected elderly patient according to the difference of the blood sodium concentration values of the to-be-detected elderly patient and the reference elderly patient at each time point and the initial heart failure performance value of the to-be-detected elderly patient. The accuracy of heart failure screening and grading evaluation of the elderly patients can be improved.

The invention belongs to the technical field of medical instruments, particularly relates to a sleep monitoring first-aid device for the neurology department, and aims to solve the problems that in the prior art, first-aid pills are easily clamped in the throat of a patient, and a first-aid scheme is not comprehensive enough, the sleep monitoring first-aid device for the neurology department comprises a bed board, U-shaped frames are slidably connected to the two sides of the bed board, and extrusion rods slidably penetrate through the U-shaped frames; a hollow rotating shaft rotationally penetrates through the interior of the extrusion rod, and pressing plates are fixedly connected to the two ends of the hollow rotating shaft; the cardiopulmonary resuscitation first-aid structure is arranged at the bottom of the pressing plate and used for carrying out cardiopulmonary resuscitation first-aid on According to the first-aid device, cardio-pulmonary resuscitation first aid and click first aid can be sequentially carried out on the patient through pressing the air bag and electric defibrillation, the first-aid function is complete, effective first aid is provided for the patient in time, pills and warm water can be rapidly mixed during first aid, and the first-aid device is convenient to use and high in practicability. The medicine can be safely and stably taken for patients.

A pill case and medication reminder system is provided. A pill case and a reminder system are in data transfer communication with one another. The system can also include a global positioning system, an accelerometer, or both. A pill case compartment is configured to hold a medication. The pill case has a sensor or sensor array configured to detect the amount of medication in the pill case. A pill case processor is configured to generate a data signal pertaining to the amount of medication in the pill case. The system can generate medication reminders, for example, pertaining to refilling a subscription or taking medication with food. The pill case can include or connect to a phone case for a smartphone, or can be integrated into a smartwatch.

The utility model relates to the technical field of medical auxiliary equipment, in particular to an intelligent medicine box with a medicine taking record, a storage assembly comprises nine groups of independent medicine boxes which are detachably installed in an outer box and are evenly distributed in the transverse direction and the longitudinal direction, cover plates are connected to the medicine boxes in a sliding mode, and opening and closing assemblies used for controlling the medicine boxes to be opened or closed are arranged in the medicine boxes. A pressure sensor located below the opening and closing assembly is fixedly connected into the medicine box, and a display panel is fixedly connected to the outer box. By means of the storage assembly, a user can set the medicine taking time of each medicine in advance according to advice and advice of a doctor. When the set time is up, the medicine box can give out clear sound, shake or flicker light to remind a user to take medicine on time. The user can take the medicine on time, and the treatment effect is improved. When a user opens the medicine box to take out medicine, the intelligent medicine box can automatically record information such as medicine taking time and medicine names. And checking and management can be carried out by connecting a mobile phone APP or other equipment.

To provide a beverage container that allows for easy administration of medication and consumption of beverages. [Solution] A beverage container 1 according to one aspect of the present invention has a main body 2 equipped with a hot water outlet 21 and a suction port 22, and a filtration member 3 having a partition 31 that is inserted into the main body from the hot water outlet 21.

Systems and methods are provided herein for using a machine learning model to select a weight loss medication to address obesity. A computing system can receive physiological measurements of a user. The computing system can apply the measurements to a machine learning model. The machine learning model can be trained using a plurality of examples, each example including sample physiological measurements of a sample user and a corresponding sample weight loss medication administered to the sample user. The computing system can generate, for the user, a metric indicative of an expected outcome related to a weight loss medication based on applying the one or more physiological measurements to the machine learning model. The computing system can provide, to a user device associated with the user, a message indicative of the expected outcome related to the weight loss medication. The computing system can improve the effectiveness of medications in addressing obesity.

The invention relates to biological medicine manufacturing, in particular to a dexmedetomidine freeze-dried composition and a preparation method thereof.The freeze-dried composition comprises active pharmaceutical ingredients and auxiliary materials, the active pharmaceutical ingredients in unit dosage are smaller than 200 micrograms, and the auxiliary materials comprise a skeleton supporting agent, an adhesive, edible essence and a sweetening agent; the skeleton supporting agent, the adhesive and the sweetening agent are all water-soluble. The freeze-drying composition disclosed by the invention can be disintegrated in the oral cavity, and the defect that the dosage of the taken medicine is greatly changed due to the condition that microgram-level effective component freeze-drying preparations stick to the bottom or fall off residues in the preparation process is overcome. In addition, the freeze-dried composition can be rapidly absorbed in the oral cavity and rapidly take effect, the first-pass effect is reduced, and the bioavailability is improved.

The invention relates to the technical field of medical auxiliary instruments, in particular to an automatic administration oral medicine storage device which comprises a box body, a driving assembly is arranged in the box body, a heating groove is formed in the upper surface of the box body, and the upper end of the driving assembly extends into the heating groove and is connected with a fixing plate; placing holes are formed in the fixing plate, medicine is placed from top to bottom according to the oral taking sequence through the multiple layers of placing plates in the three containing holes, oral medicine three times a day is contained, a water cup is placed in the placing hole, a pressure sensor is triggered, a motor is started to drive a mounting plate to drive the water cup to descend, and the oral medicine is taken out. After the temperature sensor detects that water in the water cup reaches a proper temperature, the motor is started to drive the water cup to ascend, and the rotating block drives the storage hole to replace and then triggers the air cylinder to eject medicine out, so that the elderly patient can take the medicine quantitatively in sequence in cooperation with warm water.

The medicine cup comprises a cup body, a cup cover and a cup bottom, the cup body and the cup bottom are oppositely installed on the cup body, a medicine storage cavity and a medicine storage cavity which correspond to each other are formed in the cup body and the cup bottom respectively, partition plates are arranged in the cup body and divide the medicine storage cavity into a plurality of medicine dividing cavities, medicine holes are formed in the partition plates, and the medicine dividing cavities are communicated with the medicine dividing cavities. The medicine storage cavity is communicated to the cup cover through the medicine distribution cavity and the medicine holes, and an insertion plate for sealing the medicine holes is inserted into the partition plate. Various medicines needing to be taken by a patient are placed in the corresponding medicine storage cavities respectively, then the medicines needing to be taken by the patient can be poured into the corresponding medicine dividing cavities from the medicine storage cavities according to a certain number in advance, when the medicines need to be taken, the multiple medicines needing to be taken can be poured into the cup cover in a unified mode by pulling out the insertion plates inserted into the partition plates on the same layer, and the medicine cup is convenient to use. Therefore, the medical staff can quickly and accurately distribute the medicine required by the patient, the convenience of taking medicine by taking care of the patient by the medical staff is improved, and each patient can take the medicine on time.

The present invention relates to solid pharmaceutical dosage forms suitable for use as a medication administered with drinking water. In particular, the present invention provides solid pharmaceutical dosage forms comprising a pharmaceutically active ingredient, a non-ionic surfactant with a hydrophilic-lipophilic balance (HLB) of at least 8, and a maltodextrin. The present invention also provides the use of such pharmaceutical dosage forms in veterinary medicine, and in particular as a medication administered with drinking water, as well as methods for the preparation of such pharmaceutical dosage forms.

Provided herein are systems and methods for selecting a weight loss medication using a machine learning model to address obesity. A computing system may receive physiological measurements of a user. The computing system may apply the measurements to a machine learning model. The machine learning model may be trained using a plurality of examples, each example comprising sample physiological measurements of a sample user and a corresponding sample weight loss medication administered to the sample user. The computing system may generate based on applying the one or more physiological measurements to the machine learning model, a metric indicating an expected outcome associated with a weight loss medication for the user. The computing system may provide to a user device associated with the user, a message indicating the expected outcome associated with the weight loss medication. The computing system can improve efficacy of the medication in addressing the obesity.

The present invention discloses a control method and system for a human body simulation model, which obtains multiple physiological parameters of a human body during a detection process and constructs a human body simulation model based on the multiple physiological parameters; takes medicine within a preset time and collects changes in the multiple physiological parameters; defines the change form of corresponding parts according to the changes in the multiple physiological parameters, and dynamically regulates the human body simulation model. At this time, the human body simulation model is dynamically adjusted based on the changes in the multiple physiological parameters, and the human body simulation model and the drug digestion model are further calculated to determine the effect coefficient of the medicine according to the drug digestion model and the human body simulation model, thereby accurately estimating the effect of the medicine. At the same time, the drug compensation logic is triggered based on the effect coefficient of the medicine and the human body simulation model, so as to construct the supporting part of the medicine in the drug compensation logic, so as to perform visual control on the medicine.