Anti-interference electrochemical detection sensor and manufacturing method therefor

A detection sensor, electrochemical technology, applied in the field of biochemical detection, can solve problems such as long operation time, large test error, interference, etc., to achieve the effect of ensuring accuracy and reliability, and improving detection efficiency

Pending Publication Date: 2019-04-12
GUANGZHOU WONDFO BIOTECH
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The gravimetric method and titration method not only take a long time to operate, but also have relatively large errors and low accuracy
The phosphotungstic acid reduction method has poor specificity for the detection of uric acid, and the ascorbic acid contained in the blood sample has a relatively large interference with it, resulting in a large test error
High-performance liquid chromatography has relatively high sensitivity, but it needs large-scale instruments and special devices for detection. The test requires a large amount of blood, takes a long time, and is expensive. It is only suitable for hospitals, and it is not conveni

Method used

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  • Anti-interference electrochemical detection sensor and manufacturing method therefor
  • Anti-interference electrochemical detection sensor and manufacturing method therefor
  • Anti-interference electrochemical detection sensor and manufacturing method therefor

Examples

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Effect test

Embodiment 1

[0082] Example 1 Setting up auxiliary electrodes

[0083] The reaction reagent layer was the same as that of Comparative Example 1. Vitamin C oxidase is added to the auxiliary electrode layer as an anti-interference substance of ascorbic acid.

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Abstract

The invention relates to an anti-interference electrochemical detection sensor and a manufacturing method therefor. The sensor has a reaction cell and an injection flow channel, and the injection flowchannel is connected to the reaction cell. A reaction electrode and a reaction reagent layer disposed on the detection electrode for reacting with the target detection object are disposed in the reaction cell, and the reaction reagent layer is exposed in the reaction cell. An auxiliary electrode is disposed in the injection flow channel, and the interior and/or surface of the auxiliary electrodecontains an anti-interference substance capable of reacting with an interference substance in the sample to be tested. The anti-interference electrochemical detection sensor further has an electrode connector for connecting to an external detecting device, and the electrode connector is electrically connected to the detection electrode. The anti-interference electrochemical detection sensor is provided with an auxiliary electrode in the injection flow channel in the front stage of the reaction cell, and the auxiliary electrode contains an anti-interference substance capable of reacting with the interference substance. Therefore, during the detection, the interference substances in the sample solution can be removed, the influence of the interference substances on the detection results is eliminated, and the accuracy and reliability of the detection results are ensured.

Description

Technical field [0001] The invention relates to the field of biochemical detection, in particular to an anti-interference electrochemical detection sensor and a manufacturing method thereof. Background technique [0002] In recent years, the detection of blood glucose, uric acid, lactic acid and other substances has attracted more and more attention. The detection methods mainly include gravimetric method, titration method, phosphotungstic acid reduction method, high performance liquid chromatography, enzyme-linked photometry, enzyme-linked colorimetry and electrochemical method. [0003] The gravimetric method and titration method not only have a long operation time, but also have relatively large errors and low accuracy. The phosphotungstic acid reduction method has poor specificity for detecting uric acid, and the ascorbic acid contained in the blood sample has a relatively large interference to it, and the test error is large. High-performance liquid chromatography has high s...

Claims

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Application Information

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IPC IPC(8): G01N27/26G01N27/30
CPCG01N27/26G01N27/30
Inventor 吴岸峰李文美
Owner GUANGZHOU WONDFO BIOTECH
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