A tail-suspended squirrel cage

Abstract

The invention discloses a tail-suspended squirrel cage, comprising: at least one squirrel cage unit, a rat hanging chamber is defined in the rat cage unit, a partition is slidingly arranged in the rat hanging chamber, the partition divides the rat hanging chamber into two In the rat hanging space, the sliding partition can adjust the size of the two rat hanging spaces; a suspension device is installed above each suspension space, and the suspension device includes: a sliding cross bar, a suspension spring, a suspension ring and a tail-tying mechanism. The sliding bar is slidably set on the top of the mouse hanging space, the suspension ring is set on the sliding bar, one end of the suspension spring is connected with the suspension ring, and the other end of the suspension spring is connected with the tail-tying mechanism; through the tail-tying mechanism, the The tail of the experimental rat is suspended, and the tail of the rat is firmly fixed without trauma, and will not cause tail damage, tail severed or ischemic necrosis of the rat tail, which ensures the number of samples and the accuracy of the experimental results.

Description

technical field [0001] The invention relates to a laboratory simulation device, in particular to a tail-suspended squirrel cage. Background technique [0002] Disuse muscle atrophy is a common clinical complication. Hypokinesia, aviation weightlessness, braking, etc. can cause obvious disuse muscle atrophy and affect the motor function of the human body. Therefore, how to prevent the occurrence of disuse muscle atrophy is particularly important. Muscle atrophy induced by tail-suspended mice is a commonly used animal modeling method, which is helpful for the study of muscle atrophy. [0003] The existing tail-suspended squirrel cages have many defects: [0004] 1. The existing experimental rat tail suspension methods mainly use rope ligation, tape fixation or clip fixation. However, since the rat tail is conical, the root is thick and the end is thin, the suspension rope needs to be fixed at the end of the rat tail when hanging. When hanging upside down, the experimental ...

AI Technical Summary

Problems solved by technology

When hanging upside down, the experimental rat will swing and struggle, and the tail of the rat will easily fall off if it is tied with a rope or directly suspended with ordinary clips

In addition, when the weight of the mouse is large, the hanging mouse tail is also very easy to fall off

However, if the rope is ligated too tightly, or the clip is over-clamped, the tail of the rat will be damaged, the tail will be severed, or the tail ischemic necrosis, and the experiment cannot be continued, which will affect the experimental results.

[0005] 2. The size of the cage containing the experimental mice is fixed, but the size of the experimental mice is not uniform, and with the increase of the experimental time, the experimental mice will grow up and gain weight, and the fixed size of the cage will affect the experimental results. Reduce experimental efficiency and increase experimental cost

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