Noninvasive detection system and method for early diabetes based on urine biomarkers

A technology of biomarkers and detection systems, applied in the field of non-invasive detection systems for early diabetes based on urine biomarkers, can solve the problems of limited measurement accuracy, false positives, increased risk of infection with physical and psychological pain, etc. Achieve quantitative measurement, high accuracy and sensitivity

Inactive Publication Date: 2019-11-12
BIO TECH ACADEMY CHINA
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  • Abstract
  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

Frequent blood sampling for measurement of blood glucose concentration, on the one hand, brings huge economic burden and medical expenses to diabetic patients, on the other hand, it also brings great physical and psychological pain to diabetic patients and increases the risk of infectious diseases
However, the non-invasive urine glucose test strips commonly used in the market often have false negatives and false positives due to the limited measurement accuracy, so they cannot be popularized on a large scale.

Method used

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  • Noninvasive detection system and method for early diabetes based on urine biomarkers
  • Noninvasive detection system and method for early diabetes based on urine biomarkers
  • Noninvasive detection system and method for early diabetes based on urine biomarkers

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Embodiment Construction

[0029] The present invention will be further described in detail below through specific embodiments in conjunction with the accompanying drawings.

[0030] Please refer to figure 1 , the early non-invasive detection system of diabetes based on urine biomarkers in one embodiment of the present invention includes: an emission module 10, used to emit an incident spectrum of a predetermined wavelength; The urine sugar, urine creatinine and / or urinary cystatin C react and receive the incident spectrum; the spectrum receiving module 30 is used to receive the spectrum or fluorescent signal after passing through the test strip and attenuation, and convert it into an analog signal Signal; the signal conversion module 40 is connected with the spectrum receiving module 30, and the electrical signal is converted into a digital signal; the data processing module 50 is connected with the signal conversion module 40, and calculates the urine sugar, urine creatinine, urine in the urine sample...

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Abstract

The invention discloses a noninvasive detection system and method for early diabetes based on urine biomarkers. The system includes a transmitting module for transmitting an incident spectrum of predetermined wavelength, a detection module for reacting with urine glucose, urine creatinine and / or urinary cysteine protease inhibitor C through a test strip and receiving the incident spectrum, a spectrum receiving module for receiving the spectrum or fluorescence signals that passed through the test strip and are attenuated and converting the spectrum or the fluorescence signals into analog electrical signals, a signal conversion module which is connected to the spectrum receiving module and converts the analog electrical signals into digital signals, a data processing module which is connected to the signal conversion module and calculates the magnitude of the biomarkers in urine samples according to the digital signals, and an output module which is connected to the data processing module and is used for outputting the magnitude. The system quantitatively detects the multiple markers of diabetes and complications, improves the detection accuracy and sensitivity, reduces interference,truly reflects the concentration of the urine glucose and monitors the diabetes and the complications.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a system and method for early non-invasive detection of diabetes based on urine biomarkers. Background technique [0002] With the rapid development of the national economy and the improvement of people's living standards, the number of obese people in my country has gradually increased; in addition to the rapid increase in the obese population, the growth of the elderly population has also promoted the growth of the population of diabetic patients. According to statistics, the number of diabetic patients in my country has reached 120 million at present, and the number of diabetic patients in my country will exceed 200 million in the next 10 years. At the same time, if the blood sugar control of diabetic patients is unstable, it will lead to various complications, such as diabetic cardiovascular disease, diabetic eye disease, diabetic nephropathy, diabetic neurological di...

Claims

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Application Information

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IPC IPC(8): G01N33/558G01N33/66G01N33/70
CPCG01N33/558G01N33/66G01N33/70G01N2800/042G01N21/27G01N33/54387
Inventor哈瑞·赫斯奥夫卢卡·穆桑特阿尔贝托·贝尼托·马丁马扬克·萨拉斯瓦特多洛塔·艾娃·塔塔奇瑞塔·凯撒·赫斯奥夫张贯京邹和群葛新科肖应芬唐小浪刘义
OwnerBIO TECH ACADEMY CHINA