Traditional Chinese medicine extract composition with depressive emotion regulating effect, preparation method thereof and traditional Chinese medicine preparation

A traditional Chinese medicine preparation and extract technology are applied in the traditional Chinese medicine extract composition and its preparation, in the field of traditional Chinese medicine preparations, to achieve the effects of shortening tail suspension immobility time, relieving depression and relieving the state of "behavioral despair"

Inactive Publication Date: 2020-02-11
甘肃琛蓝生物科技有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no traditional Chinese medicine composition compatible with Hypericum perforatum, Acanthopanax, and Cortex Moutan

Method used

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  • Traditional Chinese medicine extract composition with depressive emotion regulating effect, preparation method thereof and traditional Chinese medicine preparation
  • Traditional Chinese medicine extract composition with depressive emotion regulating effect, preparation method thereof and traditional Chinese medicine preparation
  • Traditional Chinese medicine extract composition with depressive emotion regulating effect, preparation method thereof and traditional Chinese medicine preparation

Examples

Experimental program
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Effect test

Embodiment 1

[0060] This example provides a method for preparing a traditional Chinese medicine composition capable of regulating depression. The traditional Chinese medicine formula composition for improving depression and sleep involved in the present invention is composed of hypericum perforatum extract, eleuthero acanthopanax extract and moutan cortex extract. The preparation method of this composition is:

[0061] Add 10 times the amount of Hypericum perforatum with 70% ethanol and heat and reflux extract twice, each time for 1.5 hours, combine the two filtrates, filter, concentrate to an extract with a relative density of about 1.12 (72°C), and spray dry to obtain a dry extract powder , wherein the content of hyperin in Hypericum perforatum extract is 1.43%;

[0062] After breaking Acanthopanax into pieces, add 10 times the amount of 80% ethanol, heat and reflux for extraction 3 times, each time for 1.0 hour, combine the decoction, filter, and concentrate the filtrate to an extract ...

Embodiment 2

[0066] This embodiment provides a preparation method of a traditional Chinese medicine extract composition with the effect of regulating depression:

[0067] Add 10 times the amount of Hypericum perforatum with 80% ethanol, heat and reflux extract twice, each time for 1.5 hours, combine the two filtrates, filter, concentrate to an extract with a relative density of about 1.12 (72°C), and spray dry to obtain a dry extract powder , the content of hyperin in Hypericum perforatum extract is 1.44%;

[0068] After breaking Acanthopanax into pieces, add 10 times the amount of 50% ethanol, heat and reflux for extraction 3 times, each time for 1.0 hour, combine the decoction, filter, and concentrate the filtrate to an extract (72°C) with a relative density of 1.12. Spray-dried dry extract powder to obtain acanthopanax extract, wherein the content of eleutheroside is 0.88%;

[0069] Add 14 times the amount of water to the Moutan cortex medicinal material, heat and recover 9 times the a...

Embodiment 3

[0072] The present embodiment provides a kind of preparation method of the traditional Chinese medicine composition that has the function of regulating depression:

[0073] Add 10 times the amount of Hypericum perforatum to 80% ethanol containing 0.1% sodium hydroxide and heat and reflux extract twice, each time for 1.5 hours, combine the two filtrates, filter, concentrate to an extract with a relative density of about 1.12 (72°C), Spray drying to obtain dry extract powder, the content of hyperin in the extract of Hypericum perforatum is 1.29%;

[0074] After breaking Acanthopanax into pieces, add 10 times the amount of aqueous solution, heat and reflux extraction for 3 times, each time for 1.0 hour, combine the decoction, filter, and concentrate the filtrate to an extract with a relative density of 1.12 (72°C), spray dry dry extract powder, wherein the content of eleutheroside is 0.64%;

[0075] Add 14 times the amount of water to the medicinal material of Moutan Cortex, hea...

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Abstract

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine extract composition with a depressive emotion regulating effect, a preparation method thereof and a traditional Chinese medicine preparation. The composition is prepared from the following traditional Chinese medicine extracts in parts by weight: 40-80 parts of hypericum perforatum extract, 10-40 parts of acanthopanax senticosus extract and 2-20 parts of cortex moutan extract. Compared with the prior art, the traditional Chinese medicine extract composition disclosed by the invention has an obvious effect of relieving the depressive emotion, and is a safe and effective dietary supplement. Meanwhile, the traditional Chinese medicine extract composition has the effects of helping sleep and the like, is small in side effect, free of dependence and smaller in taking dosage, can be prepared into various dosage forms and is suitable for wide popularization.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a Chinese medicine extract composition capable of regulating depression, a preparation method thereof and a Chinese medicine preparation. Background technique [0002] Depression is a common mood disorder, which seriously endangers people's physical and mental health. With the development of society, the pace of life is accelerated, and the competition for employment is intensified, the number of people with depression is increasing year by year. Severe depression can develop into depression, and the suicidal tendency of depression is very serious, with a suicide rate of about 15%. In addition, clinically, more than 90% of patients with mood disorders may experience sleep disorders at a certain period, so effective prevention and treatment of sleep disorders is of great significance for the relief and improvement of depression. [0003] Hypericum perforatu...

Claims

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Application Information

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IPC IPC(8): A61K36/71A61K36/65A61P25/24
CPCA61K36/38A61K36/254A61K36/71A61K36/65A61P25/24A61K2236/333A61K2236/39A61K2236/51A61K2236/331A61K2300/00A61K36/575A61K9/0056A61K9/20
Inventor 张曾亮王尚龙李文玉宗磊宗建成邹圣灿
Owner 甘肃琛蓝生物科技有限公司
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