104 results about "Hypericum perforatum extract" patented technology

The use of extracts from the plant Hypericum perforatum in the preparation of pharmaceutical compositions for the treatment of hepatitis C, chronic hepatitis C and related viruses, said pharmaceutical compositions comprising at least one extract of the plant Hypericum perforatum and optionally in addition, one or more pharmaceutically acceptable inactive components, selected from, carriers, coatings, diluents and adjuvants.

The present invention provides a composition for topical treatment of skin and mucosal membrane lesions comprising a synergistic combination of copper compound and hypericum perforatum extract.

The invention relates to a biological preparation method of a Hypericum perforatum L extractive, providing a preparation method which can utilize medicinal material resources adequately, has simple process, is suitable for large-scale production and can prepare the Hypericum perforatum L extractive in accordance with or higher than international standards. The method comprises the following steps of: drying the Hypericum perforatum L firstly and smashing into Hypericum perforatum L powder, then weighing enzyme, adding warm water in the enzyme to dissolve the enzyme, activating enzyme solution by water bath, mixing the Hypericum perforatum L powder with water, performing water bath, soaking, cooling, adjusting pH with hydrochloric acid, stirirng uniformly, heating by water bath, adding the actived enzyme solution, mixing uniformly, performing enzymolysis, filtering, abandoning the filter to obtain medicinal material powder after enzymolysis, adding ethanol and fluxing for extraction, filtering, combining the filtrate, condensing under reduced pressure, recycling ethanol, and drying to obtain the Hypericum perforatum L extractive. The invention improves the content of hypericin in the extractive and the abandoned filtrate after enzymolysis takes away a large amount of water-soluble impurities so that the moisture of the extractive is not needed to absorb again. The biological method is safe, pollution free and has simple operation and is easy for industrialized application.

The invention discloses a fowl use antiviral medicament and process for preparation, wherein the medicament is prepared from the following constituents (by weight portions) through mixing homogeneously: radix isatidis extract 3-10 parts, astragalus root extract 2-10 parts, extract of liquorice 1-5 parts, Hypericum perforatum extract 1-7 parts.

The invention discloses an anti-insomnia composition, an application of the composition, a multi-phase pulse immediate-release preparation prepared by use of the composition and a preparation method of the preparation. The anti-insomnia composition consists of a component A and a component B, wherein the component A is one or more of melatonin, melatonin analogue and corresponding salt, melatonin receptor stimulant, 5-hydroxytryptamine 2C, receptor antagonist and 5-HTP (5-hydroxytryptophan); the component B is one or more of petroselinum neapolitanum extract, melissa extract, tuber fleeceflower stem extract, chamomile extract, passion flower extract, radix paeoniae alba extract, manyprickle acanthopanax extract, polygala tenuifolia extract, hyperforin perforatum extract, flos albiziae extract, lily extract and prunella vulgaris extract. The composition and the multi-phase pulse immediate-release preparation prepared by use of the composition have the characteristic of better anti-insomnia effect than a common melatonin preparation, and can effectively solve and improve the problem of difficult sleep of human or mammals while effectively solving and improving the insomnia problems such as light sleep or dreaminess or early awakening or difficult sleep after wakeup of human or mammals.

The present invention relates to a novel purpose of hederagenin and a derivative of the hederagenin. An anti-depression test of the hederagenin and the derivative of the hederagenin shows obvious anti-depression activity, wherein, the salt derivative of the hederagenin has stronger anti-depression activity than the hederagenin; the hederagenin has stronger anti-depression activity than hederangenoside; the activities of the hederagenin and a hypericum extract are equivalent; sodium hederagenin has higher activity than the hypericum extract. The present invention has obvious pharmacological effect and stable quality; the raw material of the present invention has abundant source and cheap price and is safe with low toxin; the present invention has simple preparation technology and high yield, which provides novel medicine source for preventing, diagnosing, examining, protecting, remedying and researching on the depression and diseases directly related to the depression, is fit for the industrialization production, is easy for popularizing and applying and has very important value for developing and using Chinese officinal plant resource. Affective mental disorder is listed at top in Chinese disease general burden, and the research and manufacture of the drug for preventing and remedying the depression has obvious social benefit and economic benefit.

The use of extracts from the plant Hypericum perforatum in the preparation of pharmaceutical compositions for the treatment of hepatitis C, chronic hepatitis C and related viruses, said pharmaceutical compositions comprising at least one extract of the plant Hypericum perforatum and optionally in addition, one or more pharmaceutically acceptable inactive components, selected from, carriers, coatings, diluents and adjuvants.

The invention relates to natural plant extracts, particularly relates to a mixture of natural plant extracts and a preparation method and application of the mixture and particularly discloses extracts of lemon eucalyptus, rosemary, liquorice, cinnamon and hyperforin perforatum and application of extracts in preparation of a disinfecting agent. Natural edible plant constituents serve as effective antibiotic constituents, other natural food additive constituents such as citric acid and sodium citrate are added to prepare the pure natural plant type disinfecting agent which is safe and nontoxic, and the disinfecting agent has the good preservation effect.

The present invention relates to the preparation process of extract containing three active components including hypericin, Hyperforin and flavones in the total content not less than 50% from hypericum perforatum or other congeneric plant. The three active components are separated from the polar solvent extracted liquid via biphase extraction with non-polar solvent selected based on their difference in polarity. They are then purified separately based on their difference in acid-base property to obtain the extract A with high hypericin and flavones content and extract B with high Hyperforin content. The two extracts are merged through dissolution to obtain hypericum perforatum extract with total active component content not less than 50%. The extract has the obvious activity of resisting depression and may be used as the material of depression treating medicine or functional food.

The invention discloses an acne removal composition which includes purslane herb extract, licorice root extract, peppermint extract and hypericum perforatum extract. The mass ratio of the purslane herb extract, the licorice root extract, the peppermint extract and the hypericum perforatum extract is (1-10):(1-10):(1-10):(1-10). The acne removal composition can well be absorbed by the skin, exert effective acne removal effect by dredging pores, inhibiting bacteria and inflammation, balancing oil and promoting metabolism, and effectively improve hyperpigmentation of the acne site.

The invention relates to the technical field of feed additive, in particular to a layer chicken feed additive and a using method. The invention aims to provide a layer chicken feed additive taking hypericum perforatum as the main raw material and a using method, aiming to improve layer chicken productivity, lower egg lipid substance content, improve egg antibiosis and antioxidation performances and prevent and cure poultry bird flu. The layer chicken feed additive of the invention comprises the components of hypericum perforatum extractive, phytase and vitamin C; a carrier can be added in thelayer chicken feed additive to form dilute layer chicken feed additive, wherein the carrier adopts one of white carbon black, kieselguhr and zeolite. The using method of the layer chicken feed additive comprises: adding the layer chicken feed additive in layer chicken feed, and evenly mixing the layer chicken feed additive with the layer chicken feed in the no-light environment; sealing and packaging the feed additive; and putting the feed additive in a shady, cool and dry place without light. Layer chicken is fed twice a day, respectively in the morning and in the afternoon.

The invention discloses an effervescent beverage with fat-reducing function comprising main ingredients and auxiliary materials, wherein the main ingredients include (by weight portions) green apple essence 10-50, green tea extract 10-30, Hypericum perforatum extract 10-30, calcium gluconate 10-30, zinc gluconate 10-30, and ferrous fumarate 10-30, the auxiliary materials include (by weight ratio) lemon acid 5-20, sodium hydrogen carbonate 5-20, soluble starch 25-40, sweetener 3-8, flavoring agent 0.5-3, preservative agent 1-2. The preparing process consists of mixing main ingredients homogeneously, charging auxiliary materials, stirring homogeneously, moistening and granulating, sieving, charging disintegrating agent, lubricating agent, mixing homogenously, tabletting, dressing, checking and packaging.

The invention provides multifunctional cleansing cream which comprises, by weight, 0.1-0.5 part of myrothamnus flabellifolia leaf / stem extracts, 0.1-0.5 part of hypericum perforatum extracts, 0.1-0.5part of witchhazel extracts, 0.1-0.5 part of grape leaf extracts, 0.1-0.5 part of flores arnica extracts, 0.1-0.5 part of aesculus hippocastanum extracts, 0.1-0.5 part of Chinese ivy stem extracts, 0.01-0.1 part of hydrolyzed sodium hyaluronate, 0.05-0.1 part of decyl glucoside, 0.1-0.5 part of pH (potential of hydrogen) regulators, 20-30 parts of surface active agents, 2-35 parts of humectants and 1-8 parts of thickening agents. Various plant extracts are compatible, and the cleansing cream has various functions of preserving moisture, diminishing inflammation and the like by the aid of synergistic interaction.

The invention belongs to the field of Chinese herbal medicines, and particularly relates to a production method of a hyperforin perforatum extract. The method is characterized by comprising the following steps: pretreatment of raw materials, extraction, leaching, concentration and the like. The hypericin content in an extract product is improved on the basis of ensuring active ingredients of various components of the product.

The invention relates to a preparation method of Hypericum Perforatum P.E, which is that extraction solvent containing effective components of hypericin and pseudohypericin is obtained by alcohol leaching extraction after the hypericum perforatum raw material is pretreated by immersing in water; then after the steps of heating, distilling, concentrating and extracting, the extract rich in effective components is obtained. The invention can be directly used in dry preparation of extract powder, can also be further separated to prepare hypericin and pseudohypericin with high purity.

The invention discloses a cosmetic composition and emulsion with a breast enlarging effect. The cosmetic composition consists of the following components in parts by weight: 0.1 to 10 parts of lupulusextract, 0.1 to 10 parts of hyperforin perforatum extract, 0.1 to 10 parts of Salvia officinalis extract and 0.1 to 10 parts of saponaria leaf / root extract. The breast enlarging emulsion prepared inthe invention has the breast health effects of improving the breast skin condition, promoting the breast compactness and increasing the chest circumference, and does not contain a preservative, so that the emulsion is safe and convenient to use.

The invention discloses a preparation method of a chicken feed additive containing chitosan. The chicken feed additive comprises the following raw materials: 15-30 parts of chitosan, 10-30 parts of isomaltose hypgather, 3-6 parts of a hyperforin perforatum extract, 8-10 parts of a dandelion extract and 8-10 parts of a licorice extract. The preparation method comprises the following steps: extracting the dandelion extract, the licorice extract and the hyperforin perforatum extract respectively, and then uniformly mixing the dandelion extract, the licorice extract and the hyperforin perforatum extract with chitosan and isomaltose hypgather so as to obtain the chicken feed additive containing chitosan. The chicken feed additive can be effectively used for improving the egg laying rate, and strengthening the immunity of chicken without adding antibiotics, and is beneficial to laying environment-friendly eggs.

The invention discloses a method for preparing a hypericum perforatum extract. By the preparation method, a stable composition of the hypericum perforatum extract can be prepared, particularly a hypericin and hyperforin-containing composition. In addition, the invention also discloses a stable composition of the hypericum perforatum extract and use thereof for preparation of medicaments.

The invention relates to a capsule containing a Hypericum perforatum extract. According to the invention, through changing of the addition sequence of adjuvants in preparation of the capsule, the capsule with good disintegration efficiency and good fluidity is prepared. A preparation method for the capsule comprises the following concrete steps: uniformly mixing the Hypericum perforatum extract with a lubricant; and then adding other components, carrying out uniform mixing and filling the capsule, wherein the other components are pharmaceutic adjuvants or a composition of other active medicines and pharmaceutic adjuvants.

The invention relates to the field of animal and plant and plant application research (combination), particularly to a preparation process and method of serum for skin repairing. The serum comprises the following raw materials: a propolis extract, a honey extract, a royal jelly extract, beta-glucan, acetyl Hexapeptide-8, L-Carnosine, oligopeptide-32, oligopeptide-1, peony flower / leaf / root extract,aloe vera extract, carbomer, xanthan gum, a mung bean extract, a centellae herba extract, a plantain herb extract, a hyperforin perforatum extract, rosemary leaf water, imidazolidinyl urea, xylitol,capryloyl hydroxamic acid, glycerol, sodium hyaluronate, butanediol, and water. According to the invention, animal extracts are combined with plant extracts to prepare the skin care product having theeffects of repairing skin injuries, supplementing skin nutrition, improving skin blood circulation, updating skin cell regeneration, improving skin elasticity and softness, improving skin quality, removing skin yellow melanin and enabling skin to be white and bright.

The invention discloses a Chinese medicinal effective fraction composition for treating depression, comprising Hypericum perforatum extract containing Hypericum perforatum total flavonoids as effective fraction, Curcuma longa extract containing curcumin as effective fraction, and Panax ginseng extract containing ginsenoside as effective fraction. The invention can utilize the compatibility of the ingredients to treat depression, take multi-link, multi-path, multi-target action in soothing the liver, relieving the depressed liver, and relieving mental stress. The composition may be in the medically acceptable solid oral preparation in dosage form of such as tablet, capsule (soft capsule or hard capsule) and granule. Pharmacological research on effective fractions extracted from the formulation shows that the medicine has specific inhibitory effect on multiple depression models.

The invention provides a pharmaceutical composition which is prepared from 20-80% of hypericum perforatum extract and the balance of ginkgo leaf extract based on the weight of the pharmaceutical composition. The invention also provides a pharmaceutical preparation containing the pharmaceutical composition. In addition, the invention also provides application of the pharmaceutical composition and the pharmaceutical preparation in preparation of a medicine for treating depression. Pharmaceutical tests show that the pharmaceutical composition provided by the invention has an obvious curative effect on depression, thereby providing a new choice for clinically treating depression.

The invention discloses a natural skincare product for moisturizing, repairing and improving skin and delaying oriental skin senescence. The natural skincare product comprises the following raw materials in percentage by mass: 3% of cetyl stearate-based olive oil grease, 2% of sorbitol olive oil grease, 3% of wheat-germ oil, 5% of Australia harizonaelnut oil, 3% of shea butter, 2% of crambe seed oil, 1% of vitamin A, 5% of glycerin, 1% of provitamin B5, 1% of an alchemilla extracting solution, 1% of an arnica extracting solution, 1% of a witch hazel extracting solution, 1% of a hedera helix extracting solution, 1% of a Chinese buckeye extract, 1% of a hyperforin perforatum extract, 1% of red grapes extract, 1% of a peony root extract and 67% of water. The natural skincare product is completely prepared from pure natural raw materials, and is appropriate in ratio; a thickener and the like harmful to a human body are not added; the burden to the skin caused by the additive is reduced to the maximal extent; and the natural skincare product has the advantages of moisturizing, repairing the skin, improving the skin, and delaying senescence.

The invention takes hypericum perforatum P.E recently sold on the market as raw material, and uses a self-created molecular trapping technology to extract high-content hypericin with 30 percent to 100 percent of activity detectable component. The new natural hypericin drug with the 30 percent to 100 percent of hypericum has antiviral effect, the hypericin has a killing function on the broad-spectrum virus, and the photosensitive side effect of the hypericum is removed. The content of the hypericum is detected by HPLC to reach 30 percent to 100 percent. The preparation method of the invention is simple and quick, the product quality is even and stable, the large-scaled production is easy to realize, and the industrial production is met.

The invention relates to a traditional Chinese medicine composite for treating viral swine high fever, which is characterized by comprising the following components in parts by weight: 10-20 parts of astragalus extract, wherein astragalan is no less than 50 percent, UV; 10-20 parts of honeysuckle extract, wherein chlorogenic acid is no less than 5 percent, HPLC; 10-25 parts of hypericum perforatum extract, wherein hypericin is no less than 0.30 percent, UV; and 20-40 parts of rhubarb extract, wherein the total amount of total anthraquinone such as emodin, rhein, chrysophanol and the like is no less than 6 percent, HPLC. The traditional Chinese medicine composite is prepared by uniformly mixing the components in the proportion and finally subpackaging. The efficacies of all components of the traditional Chinese medicine composite generate the synergism to address both the symptoms and the root causes of the viral swine high fever, and therefore, the traditional Chinese medicine composite has the effects of clearing qi, letting off heat, cooling ying and detoxication, can strongly kill viruses, can also enhance the resistance of organisms, thereby efficiently treating diseases, such as hemorrhagic fever, epidemic parotitis, cheek influenza and the like, caused by viral infection fever, has enhanced and consolidated curative effect and can be produced with standardization and industrialization.

The invention discloses antibacterial gynecological gel. The antibacterial gynecological gel is prepared from the following components in parts by weight: 1 to 3 parts of a solubilizer, 2 to 3 parts of a bactericide, 80 to 92 parts of purified water, 0.8 to 1.5 parts of ginger root extract, 0.8 to 1.5 parts of Chinese wampee tree extract, 0.8 to 1.5 parts of hyperforin perforatum extract, 0.8 to 1.5 parts of artemisia capillaris extract, 0.8 to 1.5 parts of radix stemonae sessilifoliae extract, 0.8 to 1.5 parts of radix sophorae flavescentis extract, 0.8 to 1.5 parts of fructus cnidii extract and 0.8 to 1.5 parts of radix scutellariae extract, wherein the bactericide is one or a composition of two or more of a cationic bactericide, a silver ion bactericide or an ozone bactericide. According to the antibacterial gynecological gel disclosed by the invention, multiple bactericides are adopted to synergistically play an antibacterial role, so that the gel has a good antibacterial effect and also has a killing effect on staphylococcus aureus, candida albicans, escherichia coli and the like; and the antibacterial efficiency of the antibacterial gynecological gel can reach 96 percent to the maximum extent, and meanwhile, the antibacterial gynecological gel has good viscosity, humidity and comfort and has a good effect of keeping vagina health.

The invention discloses a traditional Chinese medicine combination for curing influenza and a preparation method thereof. The combination is prepared from rhizome paridis and hypericum perforatum or from the extract products of rhizome paridis and hypericum perforatum. The traditional Chinese medicine combination is a medicine for resisting H1N1 virus and H3N2 virus with high efficacy and low toxin, and has excellent effect in curing influenza.

Compositions including Serenoa repens, Echinacea and Hypericum perforatum extracts and selenium compounds for the treatment of prostate disorders, in particular for the treatment of prostate cancer, prostatitis, prostatosis and urinary incontinence.

The invention discloses a hypericin purifying method which comprises the steps of: crushing hypericum perforatum extract, ultrasonically extracting after the crushed hypericum perforatum extract is dissolved in an alcohol solution, adding a gelatin solution to remove tan to obtain a hypericum perforatum extract tan-removing solution; mixing methacrylate type polymer microspheres with distilled water for suspending, transferring into a chromatographic column, carrying out wet-process sampling on the hypericum perforatum extract tan-removing solution, carrying out gradient elution by using a water-alcohol solution system, and concentrating eluent to obtain a crude hypericin product; mixing styrene type polymer microspheres with an acetone solution for suspending, transferring into the chromatographic column, completely dissolving the crude hypericin product with the acetone solution, then carrying out the wet-process sampling, carrying out gradient elution by using the acetone solution, and processing eluent to obtain a fine hypericin product; and mixing reverse-phase silica gel filler with chromatographically pure methanol for suspending, transferring into the chromatographic column, completely dissolving the fine hypericin with the methanol, sampling, eluting with a methanol-disodium hydrogen phosphate buffer solution, mixing the same components after eluent is detected by adopting HPLC (High Performance Liquid Chromatography) to obtain the purified hypericin. The hypericin is separated and purified by using the nano microsphere materials, and the content of the hypericin is above 90 percent.