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104 results about "Hypericum perforatum extract" patented technology

Biological preparation method of Hypericum perforatum L extractive

InactiveCN101829164AIncrease profitIncrease hypericin contentNervous disorderAntiviralsWater bathsActive enzyme
The invention relates to a biological preparation method of a Hypericum perforatum L extractive, providing a preparation method which can utilize medicinal material resources adequately, has simple process, is suitable for large-scale production and can prepare the Hypericum perforatum L extractive in accordance with or higher than international standards. The method comprises the following steps of: drying the Hypericum perforatum L firstly and smashing into Hypericum perforatum L powder, then weighing enzyme, adding warm water in the enzyme to dissolve the enzyme, activating enzyme solution by water bath, mixing the Hypericum perforatum L powder with water, performing water bath, soaking, cooling, adjusting pH with hydrochloric acid, stirirng uniformly, heating by water bath, adding the actived enzyme solution, mixing uniformly, performing enzymolysis, filtering, abandoning the filter to obtain medicinal material powder after enzymolysis, adding ethanol and fluxing for extraction, filtering, combining the filtrate, condensing under reduced pressure, recycling ethanol, and drying to obtain the Hypericum perforatum L extractive. The invention improves the content of hypericin in the extractive and the abandoned filtrate after enzymolysis takes away a large amount of water-soluble impurities so that the moisture of the extractive is not needed to absorb again. The biological method is safe, pollution free and has simple operation and is easy for industrialized application.
Owner:HENAN UNIV OF CHINESE MEDICINE

Anti-insomnia composition, application of composition, multi-phase pulse immediate-release preparation prepared by use of composition and preparation method of preparation

The invention discloses an anti-insomnia composition, an application of the composition, a multi-phase pulse immediate-release preparation prepared by use of the composition and a preparation method of the preparation. The anti-insomnia composition consists of a component A and a component B, wherein the component A is one or more of melatonin, melatonin analogue and corresponding salt, melatonin receptor stimulant, 5-hydroxytryptamine 2C, receptor antagonist and 5-HTP (5-hydroxytryptophan); the component B is one or more of petroselinum neapolitanum extract, melissa extract, tuber fleeceflower stem extract, chamomile extract, passion flower extract, radix paeoniae alba extract, manyprickle acanthopanax extract, polygala tenuifolia extract, hyperforin perforatum extract, flos albiziae extract, lily extract and prunella vulgaris extract. The composition and the multi-phase pulse immediate-release preparation prepared by use of the composition have the characteristic of better anti-insomnia effect than a common melatonin preparation, and can effectively solve and improve the problem of difficult sleep of human or mammals while effectively solving and improving the insomnia problems such as light sleep or dreaminess or early awakening or difficult sleep after wakeup of human or mammals.
Owner:GUANGZHOU GONGHE MEDICINE TECH +1

Use of hederagenin and its derivatives in preparing antidepressant product

The present invention relates to a novel purpose of hederagenin and a derivative of the hederagenin. An anti-depression test of the hederagenin and the derivative of the hederagenin shows obvious anti-depression activity, wherein, the salt derivative of the hederagenin has stronger anti-depression activity than the hederagenin; the hederagenin has stronger anti-depression activity than hederangenoside; the activities of the hederagenin and a hypericum extract are equivalent; sodium hederagenin has higher activity than the hypericum extract. The present invention has obvious pharmacological effect and stable quality; the raw material of the present invention has abundant source and cheap price and is safe with low toxin; the present invention has simple preparation technology and high yield, which provides novel medicine source for preventing, diagnosing, examining, protecting, remedying and researching on the depression and diseases directly related to the depression, is fit for the industrialization production, is easy for popularizing and applying and has very important value for developing and using Chinese officinal plant resource. Affective mental disorder is listed at top in Chinese disease general burden, and the research and manufacture of the drug for preventing and remedying the depression has obvious social benefit and economic benefit.
Owner:SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY

Traditional Chinese medicine composite for treating viral swine high fever

The invention relates to a traditional Chinese medicine composite for treating viral swine high fever, which is characterized by comprising the following components in parts by weight: 10-20 parts of astragalus extract, wherein astragalan is no less than 50 percent, UV; 10-20 parts of honeysuckle extract, wherein chlorogenic acid is no less than 5 percent, HPLC; 10-25 parts of hypericum perforatum extract, wherein hypericin is no less than 0.30 percent, UV; and 20-40 parts of rhubarb extract, wherein the total amount of total anthraquinone such as emodin, rhein, chrysophanol and the like is no less than 6 percent, HPLC. The traditional Chinese medicine composite is prepared by uniformly mixing the components in the proportion and finally subpackaging. The efficacies of all components of the traditional Chinese medicine composite generate the synergism to address both the symptoms and the root causes of the viral swine high fever, and therefore, the traditional Chinese medicine composite has the effects of clearing qi, letting off heat, cooling ying and detoxication, can strongly kill viruses, can also enhance the resistance of organisms, thereby efficiently treating diseases, such as hemorrhagic fever, epidemic parotitis, cheek influenza and the like, caused by viral infection fever, has enhanced and consolidated curative effect and can be produced with standardization and industrialization.
Owner:TIANJIN SHENGJI GRP CO LTD

Antibacterial gynecological gel and preparation method thereof

The invention discloses antibacterial gynecological gel. The antibacterial gynecological gel is prepared from the following components in parts by weight: 1 to 3 parts of a solubilizer, 2 to 3 parts of a bactericide, 80 to 92 parts of purified water, 0.8 to 1.5 parts of ginger root extract, 0.8 to 1.5 parts of Chinese wampee tree extract, 0.8 to 1.5 parts of hyperforin perforatum extract, 0.8 to 1.5 parts of artemisia capillaris extract, 0.8 to 1.5 parts of radix stemonae sessilifoliae extract, 0.8 to 1.5 parts of radix sophorae flavescentis extract, 0.8 to 1.5 parts of fructus cnidii extract and 0.8 to 1.5 parts of radix scutellariae extract, wherein the bactericide is one or a composition of two or more of a cationic bactericide, a silver ion bactericide or an ozone bactericide. According to the antibacterial gynecological gel disclosed by the invention, multiple bactericides are adopted to synergistically play an antibacterial role, so that the gel has a good antibacterial effect and also has a killing effect on staphylococcus aureus, candida albicans, escherichia coli and the like; and the antibacterial efficiency of the antibacterial gynecological gel can reach 96 percent to the maximum extent, and meanwhile, the antibacterial gynecological gel has good viscosity, humidity and comfort and has a good effect of keeping vagina health.
Owner:SHANGYU LIZI BIOTECH

Hypericin purifying method

The invention discloses a hypericin purifying method which comprises the steps of: crushing hypericum perforatum extract, ultrasonically extracting after the crushed hypericum perforatum extract is dissolved in an alcohol solution, adding a gelatin solution to remove tan to obtain a hypericum perforatum extract tan-removing solution; mixing methacrylate type polymer microspheres with distilled water for suspending, transferring into a chromatographic column, carrying out wet-process sampling on the hypericum perforatum extract tan-removing solution, carrying out gradient elution by using a water-alcohol solution system, and concentrating eluent to obtain a crude hypericin product; mixing styrene type polymer microspheres with an acetone solution for suspending, transferring into the chromatographic column, completely dissolving the crude hypericin product with the acetone solution, then carrying out the wet-process sampling, carrying out gradient elution by using the acetone solution, and processing eluent to obtain a fine hypericin product; and mixing reverse-phase silica gel filler with chromatographically pure methanol for suspending, transferring into the chromatographic column, completely dissolving the fine hypericin with the methanol, sampling, eluting with a methanol-disodium hydrogen phosphate buffer solution, mixing the same components after eluent is detected by adopting HPLC (High Performance Liquid Chromatography) to obtain the purified hypericin. The hypericin is separated and purified by using the nano microsphere materials, and the content of the hypericin is above 90 percent.
Owner:SHENZHEN POLYTECHNIC
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