Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Detection method and application of common analgesic components in four base source radix curcumae decoction parts

A detection method, the technology of Jiyuan turmeric, applied in the field of analysis and detection, can solve the problems of large differences in chemical components of turmeric, lack of quality control standards for painkillers, etc.

Pending Publication Date: 2020-06-26
SHANDONG ACAD OF CHINESE MEDICINE
View PDF5 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In view of the large differences in the chemical components of turmeric in the prior art and the lack of quality control standards when used as analgesics, the present invention provides a detection method and application of common analgesic components in four kinds of Jiyuan turmeric decoction pieces. The analgesic ingredient curcumenol is used as a reference substance, which provides a new quality control standard for turmeric and further provides guidance for clinical medication

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Detection method and application of common analgesic components in four base source radix curcumae decoction parts

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] (1) Preparation of reference substance solution: Accurately weigh 5.95 mg of curcumenol standard substance, put it in a 10 mL volumetric flask, add methanol to dissolve and dilute to volume, shake well, and use it as curcumenol reference substance stock solution with a concentration of 0.595 mg ·mL -1 , Precisely draw 1 mL of curcumenol reference substance stock solution, put it in a 25 mL volumetric flask, dissolve in methanol, dilute to volume, shake well, and use it as curcumenol reference substance solution with a concentration of 0.0238 mg·mL -1 ;

[0023] (2) Preparation of the test solution: take about 1.0 g of yujin decoction pieces powder from 10 batches respectively, weigh them accurately, put them in a 100mL round bottom flask, add 25 mL of water, seal it up after weighing, soak for 1 h, and heat Reflux for 1 h, remove the round-bottomed flask after cooling, weigh again, add water to make up for weight loss, filter, transfer the medicinal solution to a centr...

Embodiment 2

[0029] (1) Preparation of reference substance solution: Accurately weigh 5.95 mg of curcumenol standard substance, put it in a 10 mL volumetric flask, add methanol to dissolve and dilute to volume, shake well, and use it as curcumenol reference substance stock solution with a concentration of 0.595 mg ·mL -1 , Precisely draw 1 mL of curcumenol reference substance stock solution, put it in a 25 mL volumetric flask, dissolve in methanol, dilute to volume, shake well, and use it as curcumenol reference substance solution with a concentration of 0.0238 mg·mL -1 ;

[0030] (2) Preparation of the test solution: take about 1.0 g of Guiyujin decoction pieces powder from 10 batches, weigh them accurately, put them in a 100mL round bottom flask, add 25 mL of water, weigh them, seal them tightly, and soak for 1 h , heated to reflux for 1 h, after cooling, remove the round bottom flask, weigh again, add water to make up for weight loss, filter, transfer the liquid medicine to a centrifug...

Embodiment 3

[0036] (1) Preparation of reference substance solution: Accurately weigh 5.95 mg of curcumenol standard substance, put it in a 10 mL volumetric flask, add methanol to dissolve and dilute to volume, shake well, and use it as curcumenol reference substance stock solution with a concentration of 0.595 mg ·mL -1 , Precisely draw 1 mL of curcumenol reference substance stock solution, put it in a 25 mL volumetric flask, dissolve in methanol, dilute to volume, shake well, and use it as curcumenol reference substance solution with a concentration of 0.0238 mg·mL -1 ;

[0037] (2) Preparation of the test solution: Take about 1.0 g of turmeric decoction pieces powder from 10 batches respectively, weigh them accurately, put them in a 100 mL round bottom flask, add 25 mL of water, seal it up after weighing, soak 1 h, heat to reflux for 1 h, remove the round-bottomed flask after cooling, weigh again, add water to make up for weight loss, filter, transfer the liquid medicine to a centrifug...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a detection method and application of common analgesic components in four base source curcuma aromatica decoction parts. The detection method comprises the following steps: preparing a curcumenol standard substance into a reference substance solution; taking a curcuma aromatica, cinnamomum cassia presl, curcuma aromatica or curcuma aromatica decoction part powder sample tobe subjected to temperature measurement, extracting with water, and taking a water extract as a test solution; injecting the reference substance solution and the test solution into a high performanceliquid chromatograph, and measuring and calculating the content of curcumenol in radix curcumae. According to the method, curcumenol which is a common analgesic component in radix curcumae is creatively taken as a reference substance, a new Qingjin quality control standard is provided, the content of curcumenol which is a common analgesic component in the four base source Qingjin water extracts can be determined through the detection method, and guidance is further provided for clinical medication.

Description

technical field [0001] The invention belongs to the field of analysis and detection, and in particular relates to a detection method and application of common analgesic components in four kinds of Jiyuan curcuma decoction pieces. Background technique [0002] Curcuma is a plant of Zingiberaceae Curcuma wenyujin Y.H.Chen et C.Ling ,turmeric Curcuma longa L. , Guangxi Curcuma Curcuma kwangsiensis S.G.Lee et C.F.Liang or Peng Curcuma Curcuma phaeocaulis Val The dry root tubers of . The first two kinds of turmeric are often called "warm turmeric" and "yellow silk turmeric", while the latter two are customarily called "laurel turmeric" or "green silk turmeric". Turmeric has a long history of medicinal use. It has the functions of promoting blood circulation and removing blood stasis, clearing heart and relieving depression, promoting qi and relieving pain, promoting gallbladder and reducing jaundice, protecting the liver, promoting bile secretion and excretion, lowerin...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G01N30/02G01N30/06G01N30/12G01N30/14G01N30/34G01N30/54G01N30/60G01N30/32
CPCG01N30/02G01N30/06G01N30/12G01N30/14G01N30/34G01N30/54G01N30/60G01N30/32G01N2030/047G01N2030/146G01N2030/324
Inventor 石典花张军戴衍朋苏本正
Owner SHANDONG ACAD OF CHINESE MEDICINE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com