75 results about "Bile secretion" patented technology

The invention discloses a preparation and application of macleyine and other medicine preparation extract from plants, its character lies in: it extracts macleyine with purity of 98% from bloodroot, and part of barberry family and buckthorn plants, and produces solid preparation, injection preparation compound with medicine accessories, the product can be used for curing heart and brain vessel diseases, and AD sufferer, at the same time, the product also has functions of analgesia, anticholinesterase functions and it can advances the bile secretion, and so on.

Provided are an in vitro culturing method for obtaining optimized hepatocyte-like cells and optimized hepatocyte-like cells obtained by using this method. The in vitro culturing method comprises the use of a sandwich cell culture method, serum-free culturing and an induction medium. The optimized hepatocyte-like cells obtained above have a structure and function close to that of primary liver cells, and the expression levels of the drug transporter, bile acid transporter and/or bile acid synthase thereof are significantly higher than that of traditional hepatocyte-like cells; the drug bile secretion index (BEI) and intrinsic biliary clearance (CL b,int) thereof are significantly higher than that of traditional hepatocyte-like cells; and the polarized expression of the drug transporter appears therein.

The invention discloses an orally-administered traditional Chinese medicine composition. The composition is prepared from traditional Chinese medicine raw materials such as desmodium, rhubarb, Herba Artemisiae Capillaris, achyranthes, Alisma orientale, tuckahoe, an animal gall product and so on, has functions of clearing heat and promoting diuresis, soothing liver and benefiting gall, regulating qi and dredging stranguria, promoting urination, promoting the secretion of bile, resisting inflammation, killing pain, relieving fever, resisting bacteria and so on, is used for treating diseases such as cholelithiasis and urinary calculus or hepatobiliary lithiasis caused by damp-heat of liver and gallbladder as well as symptoms such as right epigastric pain, upper abdomen fullness and distention, nausea, anorexia to greasiness, jaundice, yellow and greasy fur or osphyalgia, hematuria and so on, and has definite treatment effect and no apparent adverse reaction. The invention also relates to a preparation method, an administration method and a quality checking method for the orally-administered traditional Chinese medicine composition.

The invention relates to a live protection and bile secretion promotion preparation for fish and a preparation method thereof, belonging to the technical field of aquatic product compound feed additive. The method is characterized by comprising the following steps: preparing curcumin, choline chloride, hemolytic lecithin and carrier; and sufficiently mixing the components and crushing to prepare dry powder. Through the invention, the preparation process is simple, and the cost is low; based on the metabolic mechanism of fish, the liver protection and bile secretion promotion preparation for fish supplements Chinese herbal medicine as well as choline chloride of Western medicine; by combining Chinese medicine and Western medicine, the preparation regulates and controls the fat metabolism of fish, and can promote lipolysis, reduce fat deposition in liver and promote protein synthesis; and the preparation can be used for improving the immunity and oxidation resistance of fish and can promote fish growth.

The invention discloses a composite fungal intercellular polysaccharide composition with a liver protecting function and a preparation method. The composite fungal intercellular polysaccharide composition comprises 10-45 weight parts of coprinus comatus intercellular polysaccharide, 20-50 weight parts of white fungus intercellular polysaccharide and 20-45 weight parts of hohenbuehelia serotina intercellular polysaccharide. The preparation method comprises the steps of fermenting fungi, crushing the separated mycelia, adding enzyme for reacting, and separating solid and liquid phases; adding distilled water into the solid phase, then performing ultrasonic treatment, adding ethanol liquid, collecting and drying the sediment; concentrating the liquid phase, adding ethanol, standing, centrifuging to separate the sediment; combining the sediments obtained by solid and liquid phase treatment to obtain homogenous intercellular polysaccharides; and mixing the coprinus comatus intercellular polysaccharide, the white fungus intercellular polysaccharide and the hohenbuehelia serotina intercellular polysaccharide obtained by the method respectively to obtain the composite fungal intercellular polysaccharide composition with the liver protecting function. The composition has the advantages of effectively reducing the ALT (alanine aminotransferase) and AST (aspartate aminotransferase) level of serum, obviously reducing the malonaldehyde content of injured liver and obviously promoting biliary excretion so that the function of the injured liver can be recovered.

The invention relates to Chinese medicinal decoction used for treating lithiasis and a preparation method thereof, and relates to Chinese medicinal decoction for treating biliary calculus and renal calculus diseases. Main components of the decoction comprise ophiorrhiza pumila, dandelion, rhizoma sparganii, zedoary, white paeony root, herba pyrrosiae, bupleurum, Szechuan lovage rhizome, peach kernel, radix curcumae, gizzard lining, curcuma, knotgrass, gardenia, dried old orange peel, immature tangerine peel, liquorice and the like. The Chinese medicinal decoction can effectively heal intrahepatic bile duct calculus after the gall bladder is extirpated and calcification and sand-like calculus in the kidney, and simultaneously can effectively promote choleresis, improve the self-healing function of the gall bladder, and recover the functions of the gall bladder and the kidney.

A method of collecting a specimen of the present invention detects upper digestive system disease. The method of collecting a specimen includes: a step of administering a stimulant of pancreatic juice secretion or a stimulant of bile secretion to a subject; a step of positioning sampling equipment in the duodenum of the subject into which duodenal juice is secreted, the sampling equipment being used to collect and store the duodenal juice; a step of starting collection of the duodenal juice by the sampling equipment within five minutes from the administration of the stimulant of pancreatic juice secretion or the stimulant of bile secretion; and a step of stopping collection of the duodenal juice such that collection time for the duodenal juice is within five minutes from the start of collection.

The invention aims to disclose a Radix Puerariae-containing flavor fermented soya bean and a making method thereof. The Radix Puerariae-containing flavor fermented soya bean is composed of 45-55 parts of black bean, 12-15 parts of Radix Puerariae, 10-15 parts of Salvia miltiorrhiza, 8-10 parts of dried orange peel, 8-10 parts of Lotus Plumule, 5-8 parts of almond, 1-2 parts of Chinese hawthorn seed, 1-2 parts of pomegranate seed, 1-2 parts of sunflower seed, 1-3 parts of Chinese prickly ash, 10-12 parts of peanut oil, 10-15 parts of a white spirit, 10-15 parts of salt and 12-15 parts of garlic. The fermented soya bean produced in the invention is delicious and tasty and has a unique fragrance, and added Radix Puerariae can improve the regeneration capability of hepatocytes, recover normal liver functions and promote the bile secretion capability, has a certain effect on the coronary arteriosclerosis formed by hyperlipidemia, and can control cardiovascular diseases comprising the coronary heart disease, stenocardia, myocardial infarction and the like through improving the myocardial ischemia state; and Salvia miltiorrhiza can reinforce the myocardial contractility, improve the heart functions, expand the coronary artery, increase the myocardial blood flow, expand peripheral blood vessels, increase the blood flow, decrease the cerebral blood flow, increase the plasmin activities and effectively prevent thrombus formation. The Radix Puerariae-containing flavor fermented soya bean contains a plurality of traditional Chinese medicinal components beneficial for human bodies, and is beneficial for the human bodies through long-term eating.

The invention discloses a hangover alleviating radix puerariae flavor sausage and its making method. The sausage comprises the following raw materials: pork, mung beans, black beans, small red beans, Paederia scandens, dried mushroom, celery, water chestnuts, honey, pueraia vinegar, Chinese hawthorn seed powder, galangal, five spice powder, dark soy sauce, white sugar, monosodium glutamate, and white spirit. The added beans and other ingredients can enhance nutrition, and simultaneously can clearing away heat and toxic materials, tonify kidney and nourish yin. In the prepared pueraria vinegar, the pueraria can strengthen the liver and gall cell immune function, promote bile secretion, enhance liver detoxification, prevent alcohol from damaging the liver. In addition, persimmon leaves can help produce saliva and slake thirst, reduce pressure and calm the nerves. Japanese galangal flowers can regulate the middle energizer and descend qi, help digestion and eliminate wine toxins. The sausage provided in the invention has fine and tender meat quality, is sour and sweet and delicious, and is suitable for eating during drinking. Being able to reduce the damage of alcohol on the body, the sausage is particularly in line with the taste of modern people, and has good market prospects.

The invention belongs to the technical field of traditional Chinese medicine pharmacy, in particular to yinzhihuang injection and process for preparation, which comprises bacalin, honeysuckle extract, capillary artemisia extract, cape jasmine extract, and exipient. The invention effectively increases appetites of bodies through promoting bile secretion and bilirubin excretion, and plays the strong inhibition and killing effects for various sensitive avermectins through effective pharmacological components such as bacalin and chlorogenic acid and the like, and affected animals can fast recover, and the loss is reduced.

The invention discloses a simple in-vitro dynamic digestion simulation device and a use method. The in-vitro simulation digestion device comprises a simulation oral cavity part, a simulation stomach part and a simulation small intestine part which are arranged in a constant-temperature box and are connected in sequence; a first bracket, a second bracket and a third bracket are arranged in the constant-temperature box; the simulation oral cavity part is an oral cavity reaction bottle, and the oral cavity reaction bottle is hung below the first bracket; and the simulation stomach part is composed of a gastric juice storage bottle and a gastric reaction bottle, wherein the gastric reaction bottle is hung below the second bracket, and the gastric juice storage bottle is connected below the first bracket. The device is simple in structure and low in implementation cost, the gastrointestinal simulation digestion stage is not static and unchanged, the device is close to the processes of gastric secretion, gastric emptying, biliary secretion, pancreatic juice secretion and the like of the human body, and the real digestion process of the human body can be better simulated. All the parts can be split and combined, the digestion condition of one or more parts is researched by combining the actual condition, and convenience is provided for experiments.

The invention relates to quick-acting medicinal powder for protecting the liver, produced by a technology. The quick-acting medicinal powder is made through the following steps of firstly, selecting good-quality glucose, bile acid, taurine, other auxiliary materials and bentonite, uniformly mixing the raw materials to obtain a mixture, loading the mixture in a non-transparent aluminum foil bag, and performing strict sealing. The quick-acting medicinal powder is mainly used for treating hepatobiliary comprehensive symptoms of various aquaculture animals, such as fatty livers, hepatotoxicity, acute or subacute atrophy of liver, gallbladder enlargement, bile color changes and the phenomena of gill-rot, enteritis, rotted skin (red skin disease), bleeding, ulcer and the like of aquatic livestock of fish, shrimps, crabs, turtles and the like. The liver function is improved, repair of liver injury and regeneration of liver cells are facilitated, and besides, the bile secretion amount is increased. The quick-acting medicinal powder can dredge biliary tracts, eliminate cholestatis, accelerate secretion and metabolism of liver cells, and eliminate toxins, so that the poisoning reactions of the liver, the gallbladder, the kidney and the like are alleviated, the stress resistance and the disease resistance of organisms can be strengthened, and the growing performance of aquatic livestock can be improved.

The invention discloses a traditional Chinese medicine composition for treating simple obesity, and a preparation method and an application thereof. The traditional Chinese medicine composition is prepared by using 5-30 parts by mass of white atractylodes rhizome, 10-30 parts by mass of fried turtle shell, 10-20 parts by mass of inula flowers, 10-20 parts by mass of curcuma zedoary and 10-20 parts by mass of giant knotweed rhizome as raw materials. Specifically, the preparation method comprises the following steps of weighing all medicines according to the above proportions; smashing the fried turtle shell; adding water 10 times by volume that of the fried turtle shell; decocting for 30 minutes; adding traditional Chinese medicinal materials; adding water and decocting for two times, wherein the volume of added water in each time is 8-10 times that of a total mass of the medicines; and the time for each decoction is 0.5-1 hour; merging extract solutions obtained by the two times of decoction; filtering, concentrating, and drying to obtain a dry extract. Animal experiments show that the composition can significantly reduce body weight, liver weight and fat weight of high-fat obese rats, significantly reduce the contents of liver cholesterol and liver triglyceride in the high-fat obese rats, regulate lipid metabolism and improve liver functions. The medicine effects are related to the fact that the composition can increase bile flow, regulate and increase bile acid subfractions that can promote bile secretion and the lipid metabolism.

The present invention is one kind of compound Chinese medicine preparation, named icterus-eliminating capsule, for treating hepatocellular icterus and icterus caused by other causes. The Chinese medicine is prepared with capillary artemisia, lysimachia herb, red peony root, rhubarb, cape jasmine and other natural animal and plant materials, and through sorting, washing, stoving, crushing, decoction, concentration to form ointment and other steps. The Chinese medicine has the functions of promoting the function of gallbladder, eliminating icterus, promoting bile secretion, increasing the excretion of cholerythrin, lowering hemobilirubin level, repelling hepatitis B virus, stabilizing liver function and strengthening the disease resisting capacity of liver.

Provided is a stent that is placed in the bile duct to facilitate bile secretion into the duodenum. The stent includes an elastically deformable body, a film part, and an anti-inversion part. The body has a predetermined diameter and length and is formed by interlacing wires in the form of a tube. The film part surrounds to cover at least a portion of the body, extends a predetermined length from one end of the body, and is made of a flexible material. The anti-inversion part is connected to the one end of the body from which the film part extends and prevents the film part from being inverted and folded inwardly toward the body.

The invention provides a functional feed additive for protecting livers of cultured fishes and a using method thereof. Each 1000g of the additive comprises the following components: 80 to 120 g of curcumin, 120 to 180 g of 98% betaine hydrochloride, 80 to 120 g of taurine, 160 to 240 g of 80% bile acid, 30 to 80 g of silymarin, 60 to 140 g of liquorice extract and 250 to 340 g of mirabilite. The additive can quickly repair liver cells, promote bile secretion, reduce liver fat accumulation, rapidly activate body immunity and quickly return the body metabolism to normal running, can effectivelydegrade various mycotoxins in feeds and water body drug residues and relieve metabolism problems that ammonia nitrogen and nitrous acid penetrate the body as the water body worsens, can effectively scavenge free radicals, reduce damage to liver and hepatopancreas and increase the survival rate of fries and juvenile shrimps and crabs, and has significant effect on hepatopancreas swelling, hepatatrophia, red liver, yellow liver and mottled liver of shrimps and crabs.

The present invention discloses roselle flower tea and a preparation method thereof. The roselle flower tea comprises the following components in parts by weight: 4-10 parts of roselle flowers, 3-8 parts of raw dried tangerine peels, 1-5 parts of raw haws and 3-7 parts of mints. By reasonably arranging a formula of the roselle flower tea, the roselle flowers are used as a monarch drug, the dried tangerine peels, haws and mints are used as adjuvant drugs, and licorice root and crystal sugar are used as assistant drugs. The roselle flower tea can cause diuresis, lower blood pressure, promote bile secretions, balance blood lipids, regulate lipids and shape body, relieve toxins, beautify features and nourish skin, prevent atherosclerosis, protect heart and cerebral micro-vessels, improve constipation, relieve fatigue and dispel alcoholism, and is good in health-care effects. By improving the preparation technology of each of the components, the prepared roselle flower tea is good in appearance and condition. A microwave heating is used to dry each of the components. The preparation method better maintains permeability of interior conductive tissues and parenchymatous tissues in each of the components, and can well maintain appearances and structural integrity of the materials. The roselle flower tea is good in the condition and less in loss of nutrients, and achieves better color, fragrance and flavor quality.

The present application provides poria cocos, rhizoma zingiberis, red bean and coix seed tea and a preparation method thereof. The poria cocos, rhizoma zingiberis, red bean and coix seed tea is prepared from the following raw materials: 21-27 parts of red beans, 22-27 parts of coix seeds, 8-12 parts of red beans, 6-9 parts of poria cocos, 7-10 parts of gordon euryale seeds, 5-9 parts of cassia seeds, 3-7 parts of rhizoma dioscoreae, 2-6 parts of dried white gourd fruits, 1-5 parts of herba lophatheri and 1-5 parts of rhizoma zingiberis. The poria cocos, rhizoma zingiberis, red bean and coix seed tea obtained by processing the materials in proportion can promote the detoxification function of the liver, so that the liver is protected from being damaged, and bile secretion can be promoted; meanwhile, the poria cocos, rhizoma zingiberis, red bean and coix seed tea has an effect of dispelling the effects of alcohol and is suitable for people who often take social engagement to drink. The poria cocos, rhizoma zingiberis, red bean and coix seed tea can also be used for relieving diseases such as mouth and tongue sores, upset and dysphoria, cough, asthma, and swollen sore throat caused by excessive internal heat, and can also promote discharge of dampness in the body, so that symptoms such as excessive sticky and greasy phlegm caused by eczema and dampness stagnation are effectively treated.

The invention discloses a pharmaceutical composition for treating animal babesiasis. The pharmaceutical composition consists of artemisia apiacea, Tibetan capillary, rheum officinale, gentian, radix bupleuri, Chinese angelica root, akebia stem, rhizoma alismatis, rhizoma atractylodis macrocephalae, poria cocos and liquorice, wherein the artemisia apiacea is used for preventing malaria and clearing heat; the Tibetan capillary, rheum officinale, gentian and the like have the functions of removing toxicity, eliminating dampness and removing jaundice; the rhizoma alismatis and akebia stem have the functions of discharging heat and inducing diuresis; the radix bupleuri is used for soothing the liver and clearing heat while the Chinese angelica root is used for tonifying and activating blood; and the poria cocos and rhizoma atractylodis macrocephalae are used for invigorating the spleen and promoting appetite. The traditional Chinese medicine components supplement each other and cooperate to generate a synergistic effect to inhibit the DNA synthesis of babesiasis matrix, block metabolism in the babesiasis and inhibit the growth and propagation thereof, so that various symptoms such as alternate lasting high fever, anemia, jaundice, constipation and diarrhea as well as obvious emaciation of the ill animals can be effectively relieved; moreover, the pharmaceutical composition has the functions of clearing heat and removing toxicity, promoting bile secretion and dispelling babesiasis, discharging heat and cooling blood, nourishing yin and moistening dryness, activating blood and resolving stasis and tonifying blood and invigorating the stomach, and can realize perfect effects of invigorating the stomach, regulating qi and tonifying deficiency and accelerate the recovery of gastrointestinal function after babesiasis dispelling; and by reinforcing healthy qi and eliminating pathogen and treating both symptoms and root causes, the pharmaceutical composition is safe without side effects.

The invention discloses rose flower canned foods capable of promoting blood circulation and nourishing the stomach. Rose flowers are used as raw materials, and haws, apple skin, Chinese yams, red jujubes, white sugar, a little salt and an appropriate amount of water are added, so that the rose flower canned foods are prepared. The rose flower canned foods comprise many processing raw materials, the nutrient value of the rose flowers as the main material is sufficiently used, and the rose flowers and auxiliary materials are in mutual compatibility and synergistic interaction, so that the rose flower canned foods have the efficacy of promoting flow of qi and blood circulation, dispersing the depressed liver-energy, activating the spleen, promoting bile secretion, promoting digestion and regulating mechanisms. Finished products are rich in fruit flavor after being put in mouths, moderate in sour and sweet degrees, and suitable for old people and young people, and can obviously alleviate the discomfort of crowds suffering from anemia, indigestion, delicate constitution and the like after being eaten for a long term. The making process is simple and easy to realize, the transportation is convenient, market development requirements are met, batch production can be realized, and the rose flower canned foods have broad market prospect.