Application of combination of low-temperature plasma and metformin

A technology of low-temperature plasma and metformin, applied in parts of surgical instruments, medical preparations containing active ingredients, medical science, etc., can solve problems such as unclear effects and achieve the effect of inducing cell death
CN111467332AActive Publication Date: 2020-07-31SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI
2 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI
Publication Date
2020-07-31

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses application of combination of a low-temperature plasma and metformin, in particular to application of the combination of the low-temperature plasma and metformin to in-vitro non-therapeutic induction of glioma cell death. The application of the combination of the low-temperature plasma and the metformin to in-vitro non-therapeutic induction of glioma cell death shows that the combination of the low-temperature plasma and the metformin has an obvious synergistic inhibition effect on glioma cell lines U251 and U87 cultured in vitro, and can remarkably induce cell death. The application is used for non-disease treatment, but for in vitro studies, through the scheme of the application of the combination of the metformin and the low-temperature plasma to inducing gliomadeath, a new strategy can be provided for researching the application of the combination of the low-temperature plasma and the metformin to glioma treatment, and a new thought is expected to be provided for designing a new product or a new scheme for treating glioma.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to the new application of low-temperature plasma and metformin in the field, in particular to an application of low-temperature plasma combined with metformin. Background technique

[0002] Glioma is the most common primary brain tumor, among which malignant glioma (GBM) is the most malignant glioma, and its five-year survival rate is about 5%. Tumor survival has not been effectively improved. The incidence of glioma in China is about 4 / 100,000. According to the classification of central nervous system tumors in the World Health Organization in 2016, gliomas are divided into peripheral gliomas according to histopathology and mutation characteristics (WHO, grade I) and infiltrating glioma (WHO, grade II-IV), which in turn includes glioblastoma (accounting for 60-70% of all malignant gliomas), anaplastic astrocytoma (accounting for 10-15%), anaplastic oligodendroglioma and anaplastic oligoastrocytoma (10%), and some other less com...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More