Synergistic inhibition of Escherichia coli with phenol saffron red and ultrasound

A technology of phenol saffron and Escherichia coli, which is applied in the application field of the sound sensitizer phenol saffron combined with ultrasound to inhibit the activity of Escherichia coli, which can solve the problem of irrational use of antibiotics, enhanced bacterial resistance, and the number of patients Increase and other problems, to achieve the effect of overcoming bacterial resistance, high effectiveness, and promoting absorption
CN109464666BActive Publication Date: 2021-07-20LIAONING UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
LIAONING UNIVERSITY
Publication Date
2021-07-20

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Abstract

The invention relates to sonodynamic antibacterial chemotherapy and belongs to the technical field of medicine. The invention discloses an application of phenol saffron red (SB) in combination with ultrasound to inhibit the activity of Escherichia coli, wherein the compound involved is SB, and the bacterium is Escherichia coli. The synergistic effect of SB and ultrasound (US) on E. coli can effectively enhance the sensitivity of E. coli to compounds, thereby better killing E. coli or inhibiting its activity, and reducing the resistance of E. coli to the compounds used. Bacterial resistance provides a new solution. Compared with existing conventional antibacterial methods, it has higher effectiveness, safety and operability.
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Description

technical field

[0001] The invention relates to sonodynamic antibacterial chemotherapy and a bacteriostatic method, belonging to the technical field of medicine, in particular to the application of a sound sensitizer phenol saffron red (SB) combined with ultrasound to inhibit the activity of Escherichia coli. Background technique

[0002] SB is a common compound with stable physical and chemical properties, low toxicity, and easy availability. Among the dibenzoheterocyclic compounds to which the compound belongs, some compounds have been reported to have certain sound-sensitizing activity.

[0003] Due to the irrational use of antibiotics in medical treatment, the resistance of bacteria has been enhanced, resulting in a large increase in the number of patients who died of bacterial infections. The proliferation of drug-resistant bacteria has become an urgent problem related to people's health. Therefore, the desire for new methods to treat bacterial infections is becoming mo...

Claims

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