Biochemical droplet reaction device and method based on friction nano-generator

Abstract

The invention discloses a biochemical droplet reaction device based on a friction nano-generator. The device comprises a reaction generation part and a power generation part. The power generation partcomprises a friction power generation assembly and a rectification circuit. The friction power generation assembly comprises a driving electrode, a base plate, a first friction electrode, a first friction material, a second friction material and a second friction electrode which are sequentially arranged from top to bottom. A gap is formed between the first friction material and the second friction material, the first friction electrode is connected with the first friction material, the second friction electrode is connected with the second friction material, and the driving electrode, the first friction electrode and the second friction electrode are all connected with the rectification circuit. The invention also discloses a reaction method. The method is flexible to operate; cross mixing and cross contamination can be prevented, and the feasibility of multi-step reaction achieved; carrier liquid drops are arranged, so that an organic solvent is wrapped in the carrier liquid drops,and the organic solvent can move along with a movable electrode; and the stability of the liquid drops is controlled, and fusion and reaction are accelerated.

Description

technical field [0001] The invention relates to the technical field of micro-droplet control, in particular to a biochemical droplet reaction device and a reaction method based on a frictional nanogenerator. Background technique [0002] With the rapid development of biochemical technology, the demand for the improvement and optimization of its research equipment is also increasing. The development of digital microfluidics provides new ideas for biochemical reactions. The first application is continuous flow microfluidics equipment. Reagents to be reacted are pumped into digital microfluidics chips from different inlets through air pumps, valves and other devices. Converge and react in the chip. However, there are certain defects in this method. The reactants and side reactants sometimes produce solids, block the pipeline, and easily cause cross-contamination. In order to solve the above problems, a method of using liquid droplets as a closed reaction space is proposed. Ho...

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Problems solved by technology

At the same time, organic reactions often require many steps, so when using the EWOD effect to make a microfluidic chip, a large number of electrodes and complex control circuits are required. The more complicated the reaction process, the more difficult it is to make the chip

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