Biochemical droplet reaction device and method based on friction nano-generator

A technology of nanometer generators and reaction devices, which is applied in the direction of friction generators, chemical instruments and methods, and laboratory containers. Compatibility and hydrophobicity, effects of accelerating fusion and reaction

CN111604097AActive Publication Date: 2020-09-01SUZHOU UNIV
7 Cites 4 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Publication Date
2020-09-01

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses a biochemical droplet reaction device based on a friction nano-generator. The device comprises a reaction generation part and a power generation part. The power generation partcomprises a friction power generation assembly and a rectification circuit. The friction power generation assembly comprises a driving electrode, a base plate, a first friction electrode, a first friction material, a second friction material and a second friction electrode which are sequentially arranged from top to bottom. A gap is formed between the first friction material and the second friction material, the first friction electrode is connected with the first friction material, the second friction electrode is connected with the second friction material, and the driving electrode, the first friction electrode and the second friction electrode are all connected with the rectification circuit. The invention also discloses a reaction method. The method is flexible to operate; cross mixing and cross contamination can be prevented, and the feasibility of multi-step reaction achieved; carrier liquid drops are arranged, so that an organic solvent is wrapped in the carrier liquid drops,and the organic solvent can move along with a movable electrode; and the stability of the liquid drops is controlled, and fusion and reaction are accelerated.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to the technical field of micro-droplet control, in particular to a biochemical droplet reaction device and a reaction method based on a frictional nanogenerator. Background technique

[0002] With the rapid development of biochemical technology, the demand for the improvement and optimization of its research equipment is also increasing. The development of digital microfluidics provides new ideas for biochemical reactions. The first application is continuous flow microfluidics equipment. Reagents to be reacted are pumped into digital microfluidics chips from different inlets through air pumps, valves and other devices. Converge and react in the chip. However, there are certain defects in this method. The reactants and side reactants sometimes produce solids, block the pipeline, and easily cause cross-contamination. In order to solve the above problems, a method of using liquid droplets as a closed reaction space is proposed. Ho...

Examples

Embodiment Construction

[0038] In order to enable those skilled in the art to better understand the technical solutions in the present invention, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described The embodiments are only some of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present invention.

[0039] Such as figure 1 , figure 2 As shown, a biochemical droplet reaction device based on a friction nanogenerator includes a reaction generation part 10 and a power generation part 12. The power generation part 12 includes a friction power generation assembly and a rectifier circuit. Electrode 14, substrate 16, first friction elec...