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Kit for prenatal screening during pregnancy

A prenatal screening and kit technology, applied in measurement devices, instruments, scientific instruments, etc., can solve the problems of poor sensitivity, low detection rate, and complicated operation of screening methods, and achieve high detection rate and improved sensitivity. , the effect of high sensitivity

Pending Publication Date: 2020-11-17
SICHUAN ORIENTER BIOLOGICAL TECH
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  • Claims
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AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a kit for prenatal screening during pregnancy, which solves the problems of cumbersome operation, poor sensitivity and low detection rate of existing prenatal screening methods during pregnancy

Method used

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  • Kit for prenatal screening during pregnancy
  • Kit for prenatal screening during pregnancy
  • Kit for prenatal screening during pregnancy

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Experimental program
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Embodiment 1

[0028] A kit for prenatal screening during pregnancy, including polyclonal antibody 1-coated magnetic beads (3.3mL), analysis buffer (4mL), enzyme working solution (4mL), calibrator 0.5mL×6 , quality control product 1.2mL×2 sticks, the polyclonal antibody 1 is a mixture of AFP, Totalβ hCG, PAPP-A, INHA and uE3 monoclonal antibody 1, and the enzyme working solution includes the polyclonal antibody 2 labeled with enzyme , the screen-producing polyclonal antibody 2 is a mixture of AFP, Totalβ hCG, PAPP-A, INHA and uE3 monoclonal antibody 2.

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Abstract

The present invention discloses a kit for prenatal screening during pregnancy, the kit comprises magnetic beads coated with a production screening polyclonal antibody 1, an analysis buffer solution and an enzyme working solution, the production screening polyclonal antibody 1 is a mixture of AFP, Total beta hCG, PAPP-A, INHA and uE3 monoclonal antibodies 1, the enzyme working solution comprises anenzyme labeled production screening polyclonal antibody 2, and the production screening polyclonal antibody 2 is a mixture of AFP, Total BetahCG, PAPP-A, INHA and uE3 monoclonal antibodies 2. According to the invention, the magnetic beads are coated with the sieve-producing polyclonal antibody 1 and the sieve-producing polyclonal antibody 2 is marked on the enzyme to form an enzyme working solution, and the polyclonal antibodies in the sieve-producing polyclonal antibody 1 and the sieve-producing polyclonal antibody 2 are mixtures of AFP, Total beta hCG, PAPPA, INHA and uE3, so that the sensitivity of the kit can be obviously improved, and the usage is more convenient.

Description

technical field [0001] The invention relates to the technical field of chemiluminescence enzyme immunoassay, in particular to a kit for prenatal screening during pregnancy. Background technique [0002] Prenatal Screening refers to screening and diagnosing high-risk pregnant women with certain congenital defects from pregnant women through economical, simple and less invasive detection methods, so as to minimize the risk of birth defects. born. Prenatal screening can be carried out in the first trimester (10-14 weeks) and the second trimester (15-20 weeks), and the main disease for screening is Down syndrome (DS); AFP, Total β-hCG, PAPP- A, INHA, and uE3 are all important serum markers for prenatal screening. The prenatal screening system consists of in vitro diagnostic reagents, testing instruments and screening analysis software. [0003] Down syndrome, also known as congenital stupidity or trisomy 21, is the most common type of fetal birth defect. Developmental abnorma...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/543G01N21/76
CPCG01N33/54386G01N21/76
Inventor 谭春梅李玲
Owner SICHUAN ORIENTER BIOLOGICAL TECH
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