The invention belongs to the field of traditional Chinese medicine, and relates to a pharmaceutical preparation for treating early threatened abortion with positive anticardiolipin antibody and a preparation method thereof. The medicinal preparation is prepared from psoralen, Acanthopanax senticosus, Fengwei Qi, Lycium barbarum, Geshanxiao, willow parasitic, sagebrush, salvia, hairy potato and madder as medicinal raw materials. The whole recipe has few medicinal flavors, but the compatibility is reasonable, it can nourish the kidney and spleen, nourish the congenital in the future, qi to carry the fetus, blood to nourish the fetus, and tonic in the same day and day, so there is no damage. , No obvious toxic and side effects were found for mothers and infants, showing the great advantages of traditional Chinese medicine in the treatment of early threatened abortion, and it is worthy of further research and application.