Polypeptide solid-phase synthesis mechanism for preparing different derivative peptides through ultrasonic batch reaction

Abstract

The invention discloses a polypeptide solid-phase synthesis mechanism for preparing different derivative peptides through ultrasonic batch reaction. The polypeptide solid-phase synthesis mechanism comprises a reaction mechanism and a mounting cabinet, wherein the reaction mechanism is arranged in the mounting cabinet; a curved positioning part is fixedly mounted on the upper surface of a mountingbase plate; a clamping assembly is arranged on the inner side of the curved positioning part; and a reaction tank is placed on the inner side of the clamping assembly. A clamping bolt penetrates through the curved positioning part and the clamping assembly to fix the curved positioning part and the clamping assembly into a whole, so that the reaction tank is fixed and prevented from shaking to affect the reaction process in the tank; a clamping bolt penetrates through a through hole and fixing round openings; the curved positioning part and the clamping assembly form a whole; and a plurality of fixed round openings are formed in a movable penetrating groove, the clamping bolt is inserted into any fixed round opening in a penetrating mode, then the spacing distance between extrusion blocksis adjusted, a clamp adapts to reaction tanks with different diameters, and therefore the self-adaptability of the device is improved.

Description

technical field [0001] The invention relates to the technical field of polypeptide synthesis, in particular to a polypeptide solid-phase synthesis mechanism for preparing different derivative peptides through ultrasonic batch reaction. Background technique [0002] Solid-phase synthesis of peptides must contain reactive sites to which peptide chains can be attached and later removed, must be stable to the physical and chemical conditions of the synthesis, and the carrier must allow for a reaction between the growing peptide chain and reagents. In addition, the carrier must allow the provision of sufficient attachment points to give a useful yield of peptide per unit volume of the carrier, and must minimize interactions between peptide chains bound by the carrier . [0003] The peptide synthesis reaction requires a suitable temperature environment for the reaction. During the heating process, the reaction vessel will shake, but the existing device is not equipped with a mech...

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Problems solved by technology

[0005] The purpose of the present invention is to provide a polypeptide solid-phase synthesis mechanism for ultrasonic batch reaction to prepare different derivative peptides. This device is used to work, thereby solving the problems of shaking of the reaction vessel and difficult maintenance of heating components in the above background.

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