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High-hydrophilicity organic silicon hydrogel, corneal contact lens and preparation method

A technology of contact lenses and high hydrophilicity, which is applied in glasses/goggles, instruments, optics, etc., can solve the problems such as the difficulty in the preparation of silicone hydrogel materials, achieve high oxygen permeability, improve hydrophilicity, The effect of high water content

Active Publication Date: 2021-01-05
甘肃天后光学科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Silicone hydrogels are typically made by polymerizing a mixture of at least one silicone-containing monomer or macromer and at least one hydrophilic monomer, which can reduce corneal damage associated with conventional hydrogel lenses Edema and high-density vascularity, but the preparation of silicone hydrogel materials is particularly difficult due to the incompatibility of silicone and hydrophilic components

Method used

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  • High-hydrophilicity organic silicon hydrogel, corneal contact lens and preparation method
  • High-hydrophilicity organic silicon hydrogel, corneal contact lens and preparation method

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preparation example Construction

[0033] The preparation method of the contact lens is described in detail.

[0034] Among them, DHS8015 in the polysiloxane monomer was purchased from Taiwan Daxing Materials Co., Ltd.

Embodiment 1

[0036] In the present embodiment, the highly hydrophilic silicone hydrogel is composed of 5 parts by weight of TRIS, 10 parts of DHS8015, 20 parts of HEMA, 5 parts of SIGMA, 40 parts of MA, 0.6 parts of EGDMA, 0.3 parts of AIBN and 20 parts of n-hexanol were polymerized by conventional methods.

[0037] The components are mixed according to the above formula, stirred evenly, dripped into a corneal contact lens mold, thermally cured to initiate a polymerization reaction, and then placed in purified water for demoulding to obtain a silicone hydrogel contact lens.

[0038] The silicone hydrogel contact lens lens prepared by the method of this embodiment is tested after sterilization, and its light transmittance is more than 96%, the water content is 57-58%, the refractive index is 1.38-1.39, and the oxygen permeability is 41.20, the contact angle is 54.6°, and the contact angle picture is as follows figure 1 shown.

Embodiment 2

[0040] In the present embodiment, the highly hydrophilic silicone hydrogel is composed of 30 parts by weight of DHS8015, 27 parts of NVP, 10 parts of SIGMA, 6 parts of MMA, 1 part of TAC, 1 part of AIBN and 25 parts of normal Butanol is obtained by polymerization by conventional methods.

[0041] Mix each component according to the above formula, stir evenly, drop it into the corneal contact lens mold, heat cure to initiate polymerization reaction, and then place it in a sodium hydroxide solution with pH=8 to release the mold to obtain a silicone hydrogel contact lens. mirror.

[0042] The silicone hydrogel contact lens prepared by the method of this embodiment is detected after sterilization, and its light transmittance is more than 98%, the water content is 65-66%, the refractive index is 1.388-1.389, and the oxygen permeability is 55.57, the contact angle is 61.33°, the picture of the contact angle is as follows figure 2 shown.

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Abstract

The invention discloses high-hydrophilicity organic silicon hydrogel, a corneal contact lens and a preparation method, and the high-hydrophilicity organic silicon hydrogel is prepared by polymerization reaction of the following components in parts by weight: 20-40 parts of a polysiloxane monomer, 10-60 parts of a hydrophilic monomer, 0.5-6 part of a cross-linking agent, 0.3-1.5 parts of an initiator and 20-50 parts of a solvent. According to the formula, a silicon synthetic material SIGMA and / or TRIS and / or DHS8015 is used as a silicon-containing organic matter, the problem that in the prior art, a silicon monomer and a hydrophilic monomer are insoluble is solved, the hydrophilicity of the silicon hydrogel is improved, the prepared silicon hydrogel corneal contact lens is brighter, and thesilicon hydrogel has high oxygen permeability and high water content and can be used as a corneal contact lens. Therefore, the silicone hydrogel corneal contact lens is more comfortable to wear.

Description

technical field [0001] The invention relates to the technical field of silicone hydrogel, in particular to a highly hydrophilic silicone hydrogel and a corneal contact lens prepared by using the silicone hydrogel. The invention also relates to a highly hydrophilic silicone hydrogel The preparation method of glue and corneal contact lens. Background technique [0002] Human eyes, like other parts, need sufficient oxygen and need to breathe freely. Most of the oxygen in the eyes is obtained directly from the air. The traditional hydrogel lens has insufficient oxygen permeability, which seriously hinders the oxygen intake of the eyes when the patient wears it. If you wear it for a long time, it will cause adverse phenomena such as red eyes, dry eyes, etc., and even damage the cornea. [0003] At present, the soft contact lenses made of hydrogel polymers are still accepted by the public in the market. Its oxygen permeability is proportional to its water content, and the water i...

Claims

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Application Information

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IPC IPC(8): C08F220/06C08F220/20C08F230/08C08F222/14C08F226/10C08F220/14C08F216/12C08F222/20G02C7/04
CPCC08F220/06C08F230/085C08F226/10G02C7/049C08F220/20C08F222/102C08F220/14C08F216/125
Inventor 白茹唐钰喜李卓张丽珂温浩浩
Owner 甘肃天后光学科技有限公司
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