The invention discloses a preparation method of an antifogging coating solution for spectacle lenses, and relates to the technical field of lens protection solutions. The preparation method of the antifogging coating solution for the spectacle lens comprises the following steps: adding the nonionic surfactant into the diluent, performing stirring, adding the anionic surfactant after uniformly stirring, and continuously performing stirring until uniform mixing; heating the mixed solution, skimming floating foam on the upper layer of the mixed solution after heating, performing standing, performing cooling to room temperature, adding the mixed solution into a stirrer, adding the aloe extract into the stirrer, performing stirring, adding sodium ascorbyl phosphate, continuously performing stirring, finally adding the antibacterial agent, and performing stirring again to obtain the antifogging coating solution. The solution prepared by the method has good lens antifogging performance, can effectively reduce the influence of lens fogging on a user in the use process, has practicability, and can meet the requirements of the user.