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Screening system for patients with panic disorder

A technology of panic and disorder, which is applied in the field of screening methods for panic disorder, and can solve the problems of lack of early diagnosis methods for panic disorder

Active Publication Date: 2021-01-12
PEKING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is still a lack of effective early diagnosis methods for panic disorder. The present invention mainly screens and intervenes panic disorder patients through the generalization of attention regulation of pre-startle reflex inhibition.

Method used

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Embodiment Construction

[0034] The present invention is described in further detail below in conjunction with specific examples.

[0035] 1. Test preparation

[0036] In the preparation stage, the subjects sit in a quiet environment (an anechoic room or a shielded room is ideal), and electrodes are installed on the subjects (electrode 1. 10 mm below the pupil; electrode 2: the outer side of electrode 1 near the corner of the eye; ground electrode located on the mastoid). After the electrodes were installed, sounds were played to the subjects through earphones, and at the same time, the EMG activity within the time window of 500 ms from the startle stimulus or the prepulse stimulus was started to be recorded.

[0037] 2. Test process

[0038] The subjects first adapted to the background noise for 5 minutes. Afterwards a PPI test is performed. In general, the test was divided into two trials: prepulse stimulus + startle stimulus and startle stimulus only. For the trial of prepulse stimulation + st...

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Abstract

The invention discloses a screening system for patients with panic disorder. The screening system comprises a signal playing unit, a signal acquisition unit and a signal processing platform. Comparedwith a past startle reflection prepulse suppression detection system, the prepulse stimulation played by the signal playing unit uses monosyllabic or bisyllabic voice signals for the first time, the monosyllabic or bisyllabic voice signals comprise fear emotion voice, common negative voice and neutral word voice, and then semantic processing of the prepulse stimulation signals is introduced for the first time. Indexes calculated by the signal processing platform comprise startle reflection and the amplitude of prepulse suppression of the startle reflection, and the generalization effect of fear emotion attention and space attention on PPI adjustment is investigated, so that panic obstacle screening guidance suggestions are given. According to the system disclosed by the invention, rapid, simple, convenient and objective panic obstacle screening can be performed on major social events.

Description

technical field [0001] The invention belongs to the technical field of biology and new medicine, and specifically relates to a screening method for panic disorder, which takes the generalization of the attention adjustment of pre-startle reflex suppression as the key technical paradigm, including the use of negative vocabulary audio as stimulating materials and the orbicularis Myoelectricity as a key signal related technology. Background technique [0002] A sudden strong sensory stimulus will trigger the whole-body reflex activity of people or animals, which is called startle reflex. cognitive activities that interfere with normal cognitive processing. However, if a weak stimulus that is not sufficient to cause the startle reflex (ie, prepulse stimulation) is presented before a strong stimulus, it will inhibit the subsequent startle reflex, which is called prepulse inhibition of the startle reflex (prepulse inhibition, PPI) . PPI is a widely used sensorimotor gating meas...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/389A61B5/395A61B5/397A61B5/16A61B5/00
CPCA61B5/165A61B5/7235
Inventor 李量丁宇曲天书
Owner PEKING UNIV
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