Drug for preventing and treating eel Edwardsiosis and preparation method thereof
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A drug and eel technology, applied in the field of fishing medicine, can solve the problems of large economic loss, eel death, no medicine available, etc., achieve the effects of less toxic and side effects, better feeding situation, and eliminate body surface congestion
Active Publication Date: 2021-12-14
JIMEI UNIV
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For a long time, antibiotics and chemical synthetic antibacterial drugs have been used to prevent and treat diseases caused by Edwardsiella infection. However, due to the extensive and long-term use of antibacterial drugs, the drug resistance of Edwardsiella continues to increase, and the current international strict restrictions on the use of antibiotics in eel products The residual amount of chemical drugs leads to the situation that there is no drug available in eel farming production. Once infected with Edwardsiella, it will cause a large number of eels to die and cause huge economic losses.
At present, there is no efficient, green and safe plant-derived drug that has been developed to prevent and treat Edwardsiella infection in the current fishery drug market
Method used
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preparation example Construction
[0031] The present invention also relates to one of the preparation methods of the above-mentioned eel Edwardsiosis prevention and treatment drug, comprising the following steps:
[0032] Step (11), according to the dosage ratio, decoct Galla chinensis, Scutellaria baicalensis, Hedyotis diffusa, and Gallus chinensis with 10 times of water for three times, each time for 1.5 hours, combine the decoctions, let stand, filter, and concentrate the filtrate to relative density The clear ointment with a Baume degree of 1.25-1.28 at 60°C is ready for use;
[0033] Step (12), according to the dosage ratio, with Angelica dahurica, Polygonum cuspidatum, Houttuynia cordata, Andrographis paniculata, Purslane, Radix Glycyrrhizae, reflux three times with 70% ethanol by mass percentage, each time for 2 hours, combine the extracts, reclaim ethanol, filter, Concentrate the filtrate to a clear paste with a relative density of 60°C and a Baume degree of 1.25 to 1.28 for later use;
[0034] Step (...
Embodiment 1
[0055] The best formula: in terms of mass, gallnut 3g, scutellaria baicalensis 1g, angelica dahurica 1g, polygonum cuspidatum 10g, andrographis paniculata 10g, hedyotis diffusa 20g, houttuynia cordata 20g, chicken bone grass 10g, purslane 25g, licorice 10g.
Embodiment 2
[0057] According to the quantity in grams, there are gallnut 2g, scutellaria baicalensis 3g, angelica dahurica 2g, knotweed cuspidatum 5g, andrographis paniculata 5g, hedyotis diffusa 20g, houttuynia cordata 20g, chicken bone grass 15g, purslane 18g, and licorice 10g.
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Abstract
The invention discloses a medicine for preventing and treating Edwardsiella disease of eel and a preparation method thereof. The medicine formula is as follows: 1-5 parts of gall, 1-5 parts of skullcap, 1-5 parts of angelica, 5-15 parts of knotweed, and 5-15 parts of andrographis paniculata 10 to 50 parts of Hedyotis diffusa, 5 to 30 parts of Houttuynia cordata, 5 to 15 parts of Chickweed, 5 to 50 parts of purslane, and 5 to 30 parts of licorice. Toxin, hemostasis, Angelica dahurica for removing blood stasis and expelling pus, promoting muscle and relieving pain, Polygonum cuspidatum promoting blood circulation, dissipating blood stasis, Andrographis paniculata and Portulaca oleracea to detoxify, reduce inflammation and relieve pain, protect liver and protect liver, Hedyotis diffusa clears heat and detoxifies, relieves pain and disperses knots , Houttuynia cordata antibacterial, enhance immunity, chicken bone grass clearing heat and detoxification, soothing liver and relieving pain, licorice clearing heat and detoxification, invigorating spleen and nourishing qi, reconciling the effects of various medicines, can effectively eliminate eel pectoral and anal fin surface bleeding, liver and kidney enlargement , congestion, ulcers, gastrointestinal effusion and other diseases, with reasonable formula, fast onset, safe and non-toxic, stable efficacy and so on.
Description
【Technical field】 [0001] The invention relates to a fishing medicine, in particular to a medicine for preventing and treating bacterial diseases of eel caused by Edwardsiella infection, redness of eel's pectoral fin and anal fin congestion, hepatic and kidney enlargement, congestion, ulcer, gastrointestinal effusion, etc. Preparation. 【Background technique】 [0002] Edwardsiella disease, also known as liver and kidney disease, is more common in Japanese eels, European eels, and American eels. The popular season is the high temperature period in summer, and it often occurs in the spring seedling cultivation period due to the introduction of live bait silk earthworms. It is an acute disease in the juvenile stage, and a chronic disease in the young eel and adult eel stages. The pathogen is Edwardsiella tarda, Edwardsiella zhejiang, or Edwardsiella fujian, which is one of the main pathogens of eel breeding diseases. Taxonomically, Edwardsiella belongs to the genus Edwardsiella...
Claims
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