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Nursing pharmaceutical composition used before operative anesthesia and preparation method thereof

A composition and drug technology, applied in the direction of drug combination, preparation of sugar derivatives, anesthetics, etc., can solve the problems of high cost and complex drug ingredients, and achieve low dosage, simple and easy preparation method, and low equipment dependence Effect

Pending Publication Date: 2021-03-02
CHENGDU ZHIA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the drug ingredients used are more complex, the cost is higher, and the efficacy needs to be further improved

Method used

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  • Nursing pharmaceutical composition used before operative anesthesia and preparation method thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0025] A nursing pharmaceutical composition for operation before anesthesia, characterized in that it comprises the following components in parts by weight: 0.08 parts of sucralose modified atropine taurate, 2 parts of leek seed extract, 3 parts of grass extract, 2 parts of apigenin, 1 part of drunk horse grass extract, 2 parts of jade hibiscus extract, 8 parts of Chinese herbal medicine extract.

[0026] The preparation method of the sucralose-modified atropine taurate comprises the following steps: adding sucralose and atropine to a solvent, stirring and reacting at 40° C. for 6 hours, and removing the solvent by rotary evaporation, and preparing the obtained crude Product and taurine are added into water, stirred and reacted at 60° C. for 5 hours, and the water is removed by rotary evaporation to obtain sucralose modified atropine taurine; the mol ratio of the sucralose, atropine, and solvent is 1: 3:15; the solvent is water; the mol ratio of the crude product, taurine, and...

Embodiment 2

[0031] A nursing pharmaceutical composition for operation before anesthesia, characterized in that it includes the following components in parts by weight: 0.09 parts of sucralose modified atropine taurate, 2.5 parts of leek seed extract, huixin 3.5 parts of grass extract, 3 parts of apigenin, 1.5 parts of drunk horse grass extract, 2.5 parts of jade hibiscus extract, 8.5 parts of Chinese herbal medicine extract.

[0032]The preparation method of the sucralose-modified atropine taurate comprises the following steps: adding sucralose and atropine to a solvent, stirring and reacting at 45° C. for 6.5 hours, and then rotating to remove the solvent, and the obtained crude Product and taurine are added into water, stirred and reacted at 65° C. for 6 hours, and the water is removed by rotary evaporation to obtain sucralose modified atropine taurine; the mol ratio of the sucralose, atropine, and solvent is 1: 3:16; the solvent is ethanol; the mol ratio of the crude product, taurine, ...

Embodiment 3

[0037] A nursing pharmaceutical composition for operation before anesthesia, characterized in that it includes the following components in parts by weight: 0.11 parts of sucralose-modified atropine taurate, 3 parts of leek seed extract, huixin 4 parts of grass extract, 3.5 parts of apigenin, 2 parts of drunk horse grass extract, 3.5 parts of jade hibiscus extract, 9 parts of Chinese herbal medicine extract.

[0038] The preparation method of the sucralose-modified atropine taurate comprises the following steps: adding sucralose and atropine to a solvent, stirring and reacting at 50° C. for 7 hours, and removing the solvent by rotary evaporation, and preparing the obtained crude Product and taurine are added into water, stirred and reacted at 70° C. for 6.5 hours, and the water is removed by rotary evaporation to obtain sucralose-modified atropine taurine; the mol ratio of the sucralose, atropine, and solvent is 1: 3:18; the solvent is N,N-dimethylformamide; the molar ratio of ...

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Abstract

The invention discloses a nursing pharmaceutical composition used before operative anesthesia and a preparation method of the nursing pharmaceutical composition. The composition comprises the following components in parts by weight: 0.08-0.15 part of sucralose modified atropine taurate, 2-4 parts of a Chinese chive seed extract, 3-5 parts of a rhodobryum roseum extract, 2-5 parts of apigenin, 1-3parts of an achnatherum inebrians extract, 2-5 parts of a cotton rose hibiscus extract and 8-10 parts of a Chinese herbal medicine extract. The invention further provides the preparation method of thenursing pharmaceutical composition used before operative anesthesia. The nursing pharmaceutical composition used before operative anesthesia is small in toxic and side effect, good in medicine effectand low in dosage, can effectively relieve tension and anxiety of a patient, reduce secretion of saliva and respiratory tract secreta of the patient and prevent intraoperative and postoperative pulmonary complications, and can effectively improve the pain threshold of an operative patient after being applied before anesthesia.

Description

technical field [0001] The invention relates to the technical field of surgical nursing medication, in particular to a nursing pharmaceutical composition used before surgical anesthesia and a preparation method thereof. Background technique [0002] Life, death, sickness and old age are natural laws. On the road of life, illness is unavoidable. Illness brings endless pain and suffering to patients. How to quickly alleviate the suffering of patients and save their lives in time is the mission of medical workers and scientific researchers. Currently, surgical treatment is the most important medical method. Since doctors need to use medical instruments to perform destructive operations such as excision and suture on patients during the operation, the patient needs to be anesthetized before the operation to reduce the pain of the patient and ensure the smooth progress of the operation. Clinical anesthesia is the main part of modern anesthesiology. Involving all the treatment ...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61K36/8964A61K47/54A61P23/00A61P25/00C07H1/00C07H5/02A61K35/618A61K31/46A61K31/352
CPCA61K31/352A61K31/46A61K35/618A61K36/068A61K36/10A61K36/23A61K36/27A61K36/33A61K36/48A61K36/482A61K36/486A61K36/66A61K36/714A61K36/81A61K36/88A61K36/8884A61K36/8962A61K36/8964A61K36/899A61K47/549A61P23/00A61P25/00C07H1/00C07H5/02A61K2300/00
Inventor 周昌发
Owner CHENGDU ZHIA TECH CO LTD
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