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Model for evaluating gastric cancer prognosis based on Lauren typing and postoperative residual lymph nodes and application

A lymph node and prognosis technology, applied in the field of biomedical detection, can solve problems such as inability to accurately guide prognosis and inability to accurately assess changes in the overall tumor burden of gastric cancer

Pending Publication Date: 2021-05-25
ZHONGSHAN HOSPITAL FUDAN UNIV
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AI Technical Summary

Problems solved by technology

Therefore, this standard cannot accurately evaluate the changes in the overall tumor burden after neoadjuvant chemotherapy for gastric cancer, nor can it accurately guide the prognosis.

Method used

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  • Model for evaluating gastric cancer prognosis based on Lauren typing and postoperative residual lymph nodes and application
  • Model for evaluating gastric cancer prognosis based on Lauren typing and postoperative residual lymph nodes and application
  • Model for evaluating gastric cancer prognosis based on Lauren typing and postoperative residual lymph nodes and application

Examples

Experimental program
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Effect test

Embodiment

[0042] For example, the patient visited the doctor on June 1, 2020, aged 60, female. 2020-1-8 Diagnosis of locally advanced gastric adenocarcinoma, Lauren type diffuse type. 2020-1-20 Start DOS regimen neoadjuvant chemotherapy. Radical surgery for gastric cancer was performed on May 25, 2020. The postoperative pathology of the patient is as follows: (total gastric) ulcerative adenocarcinoma, cancer tissue infiltrates the submucosa of the gastric wall, tumor thrombi are seen in the vessels, fibrous tissue hyperplasia around the tumor, and inflammatory cell infiltration, consistent with the changes after treatment, residual tumor cells occupy the original tumor bed 80%, lymph nodes 0 / 31.

[0043] In this case, when the patient was diagnosed with gastric cancer, Lauren typed diffuse type, and the data index of the risk factor was 2 points.

[0044] In this case, the patient had 0 residual lymph nodes after radical gastrectomy, and the risk factor data index was 1 point.

[0045...

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Abstract

The invention relates to a model for evaluating gastric cancer prognosis based on Lauren typing and postoperative residual lymph nodes and application, and belongs to the technical field of biomedical detection. According to the invention, the number of residual lymph nodes after Lauren typing and neoadjuvant chemotherapy is comprehensively used as a prognosis evaluation index after neoadjuvant chemotherapy of gastric cancer, and a prognosis evaluation model for patients after neoadjuvant chemotherapy of gastric cancer is established. Through clinical verification, the evaluation model can effectively pre-judge disease outcome after neoadjuvant chemotherapy of gastric cancer, and is more accurate than the traditional Japan JGCA standard and German Becker standard. The invention provides reference information for prognosis of tumor patients, so that clinical doctors are helped to formulate the most reasonable diagnosis and treatment plan for the tumor patients, and timely and effective doctor-patient communication is facilitated.

Description

technical field [0001] The invention relates to a model and application for evaluating the prognosis of gastric cancer based on Lauren classification and postoperative residual lymph nodes, and belongs to the technical field of biomedical detection. Background technique [0002] Tumor is one of the most important diseases threatening human health. Although the diagnosis and treatment of tumors has been developed rapidly, the prognosis of a large number of cancer patients is still not optimistic. Gastric cancer is a major disease that seriously affects human health worldwide, and currently accounts for the third cause of cancer death worldwide. my country is a country with a high incidence of gastric cancer. In 2015, gastric cancer ranked second in the number of new cancer cases and deaths in my country. Due to atypical early symptoms and lack of popularization of gastroscopic routine examination, the disease population in my country has the characteristics of late stage an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H50/30G16H20/40
CPCG16H50/30G16H20/40
Inventor 王妍刘天舒纪元汪学非
Owner ZHONGSHAN HOSPITAL FUDAN UNIV
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