Streptococcus sp.64 and application thereof

A technology of fermentation broth, streptococci, applied in the field of microbiology

Active Publication Date: 2021-07-09
HAINAN MEDICAL COLLEGE
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, with people's long-term research and development, obtaining new antibacterial active substances has gradually become a major problem in microbial screening.

Method used

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  • Streptococcus sp.64 and application thereof
  • Streptococcus sp.64 and application thereof
  • Streptococcus sp.64 and application thereof

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Embodiment Construction

[0027]The present invention will be further described below in conjunction with specific examples, so as to better understand the present invention.

[0028] The invention provides a streptococcus, which is a new species in the genus Streptococcus, named: Streptococcussp. -09-16. The Streptococcus sp.64 of the present invention is obtained by separating and screening the intestinal tract samples of Rattus norvegicus in the central mountainous area of ​​Hainan Island.

[0029] 1 Morphological Observation of New Species of Streptococcus

[0030] 1.1 Source of strain

[0031] Intestinal specimens of Rattus norvegicus from Hainan Island. Take the intestinal mucosal specimen of healthy adult Rattus norvegicus, cut the intestinal tissue of Rattus norvegicus by aseptic operation and put it into a grinder for grinding (about 20mg). Dilute, then transfer to a 2ml sterile centrifuge tube filled with 1.5ml PBS, vortex at high speed, then centrifuge at 1500rpm at low speed, carefully ...

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Abstract

The invention provides a streptococcus, which is a new species in streptococcus, is named as Streptococcus sp.64, is registered and preserved in Guangdong Microbial Culture Collection Center, and has a preservation number of GDMCC No: 61194. The Streptococcus sp. 64 disclosed by the invention can generate relatively strong bacteriostatic active substances after being subjected to fermentation culture, has a relatively obvious bacteriostatic effect on pseudomonas aeruginosa, burkholderia pseudomallei and the like, has a wide development space in prevention and treatment of diseases caused by the pseudomonas aeruginosa, the burkholderia pseudomallei and the like, and has the good development and application prospects in the aspect of antibacterial drugs.

Description

technical field [0001] The invention belongs to the field of microorganisms, and in particular relates to a strain of Streptococcus sp.64 and its application. Background technique [0002] Streptococcus is the type genus of Firmicutes, Bacilli, Lactobacillales, and Streptococcusaceae. The genus Bacteria is a common type of pyogenic coccus, which widely exists in nature, human and animal feces and nasopharynx of healthy people, and most of them are not pathogenic. Medically important streptococci mainly include Streptococcus pyogenes, Streptococcus viridans, Streptococcus pneumoniae, and Streptococcus agalactiae. With the continuous progress and development of bacterial isolation and identification methods, especially the wide application of molecular classification and identification methods, more and more streptococci have been discovered. At the same time, as of 2020, the genus has included 160 species and 29 subspecies (http: / / www.bacterio.net / streptococcus.htmL). Rese...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12N1/20A61K35/744A61P31/04C12R1/46
CPCA61K35/744A61P31/04
Inventor 牛莉娜轩断断张勇吕刚胡守奎尹飞飞杜江张云唐川宁崔秀吉黄艺彭箬岩
Owner HAINAN MEDICAL COLLEGE
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