Micro-fluidic chip capable of removing bubbles

Abstract

The invention discloses a micro-fluidic chip capable of removing bubbles; the top of a chip body is provided with an annular gas communication pool, the inner bottom of the gas communication pool is provided with a concave gas filtering pool and a reaction pool, the inner bottom of the gas communication pool is covered with a hydrophobic filter membrane, and the gas communication pool and the gas filtering pool as well as the gas communication pool and the reaction pool are separated by the hydrophobic filter membrane; a gas hole communicated with the gas communication pool is formed in the area, corresponding to the gas communication pool, of the upper cover plate; a sample adding pool is formed in the center of the chip body; a sample adding hole communicated with the sample adding pool is formed in the position, corresponding to the sample adding pool, of the upper cover plate; the bottom of the sample adding pool is communicated with the gas filtering pool through a first channel; and the bottom of the gas filtering pool is communicated with the reaction pool through a second channel. The influence of bubbles on the detection result in the sample detection process can be avoided, so that the accuracy of the detection result is improved. The chip is small in size, does not need mechanical driving force for sample adding, is convenient to use, and is suitable for various POCT scenes.

Description

technical field [0001] The invention relates to the technical fields of biochemical detection and microfluidic chips, and more specifically relates to a microfluidic chip capable of removing air bubbles. Background technique [0002] Photochemical colorimetry is a method of qualitative or quantitative analysis based on the absorption characteristics of colored substances to specific wavelengths of light, by comparing or measuring the changes in the optical properties of the measured solution or the colored solution generated after adding an indicator. This method has the advantages of low cost, simple operation, fast response, etc., and is widely used in the field of biochemical detection. [0003] However, for the detection of some biochemical samples, more complicated procedures such as sample pretreatment and biochemical reactions are required, which greatly limits its application in non-laboratory conditions. In recent years, with the development of microfluidic technol...

AI Technical Summary

Problems solved by technology

In addition, the gas contained in the experimental sample can also lead to the formation of bubbles

It is often difficult to completely remove air bubbles from the channel due to channel size limitations

The existence of these bubbles may have some impact on the accuracy of photochemical detection results, especially for experiments that require heating liquids

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